"Tumor shrinkage" refers to the reduction in size or volume of a tumor. It means that the tumor has become smaller, often as a result of medical treatment or intervention.
Full definition
Piroxicam is a non-steroidal anti-inflammatory drug (also known as an NSAID) that has offered benefit both in alleviating symptoms due to inflammation in many dogs, as well as causing actual
tumor shrinkage in some dogs.
Adding cisplatin to the standard gemcitabine / nab - paclitaxel drug treatment provided a very high rate
of tumor shrinkage for patients with advanced pancreatic cancer, according to the results of a pilot clinical trial conducted by the HonorHealth Research Institute and the Translational Genomics Research Institute (TGen).
Pai notes cancer patients may
see tumor shrinkage within the first three months on the ketogenic diet.
Trebananib does not increase the risks of hypertension (high blood pressure) and bowel perforation like bevaciuzmab, but still has a similar impact
on tumor shrinkage and delaying cancer progression, research shows.
Of 10 men whose metastatic cancers could be measured with imaging scans, five
experienced tumor shrinkage by more than half, including one man whose cancer completely disappeared.
Two patients with advanced infantile fibrosarcoma experienced sufficient
tumor shrinkage with larotrectinib to allow for limb - sparing surgery with curative intent; both patients had negative margins after surgery, and they both remained progression - free without larotrectinib treatment after 4.8 and 6.0 months of follow - up.
And using lower levels of Yervoy in combination with Opdivo actually prompted
more tumor shrinkage, underscoring the fact that dosing is a critical and unpredictable factor for immunotherapies.
«In the past, we assumed a healthy immune system would fight off the virus infection before it could
cause tumor shrinkage.
«In the tumor sample from a patient with high NRP - 1 expression, there was a significant improvement in the efficacy of the nanoparticle to
induce tumor shrinkage,» said Nel.
The experimental device is being tested in cancer patients to see whether it can be tuned to accurately
measure tumor shrinkage in response to therapy.
«We are looking to optimize the combinations of targeted therapies and the scheduling of those therapies so we can
improve tumor shrinkage and minimize potential toxicities for a patient,» said Andrew Aplin, PhD, Associate Director for Basic Research and the Program Leader for Cancer Cell Biology and Signaling (CCBS) in the NCI - designated Sidney Kimmel Cancer Center at Jefferson Health.
«We demonstrated that the co-administration of the iRGD peptide with the particles can enhance the effectiveness of pancreatic cancer treatment in the tumor model, leading to
increased tumor shrinkage, disappearance of metastases and enhanced animal survival» said Meng, an adjunct assistant professor of nanomedicine.
Kidney cancer patients may see long -
lasting tumor shrinkage with immunotherapy, which uses the immune system as a weapon to fight cancer.
«We treated these three patients with drugs that attack these genetic alterations and
saw tumor shrinkage.
That is why researchers more often rely on faster - developing indicators of (apparently) improved health:
tumor shrinkage in cancer, lowered blood - sugar levels in diabetes, reduced brain plaque in Alzheimer's, lowered bad cholesterol or elevated good cholesterol in heart disease.
The
significant tumor shrinkage and immunologic changes observed support a complementary role of SBRT and PD - 1 immunotherapy, investigators concluded.
Trebananib does not increase the risks of hypertension (high blood pressure) and bowel perforation like bevaciuzmab, but still has a similar impact
on tumor shrinkage and delaying cancer progression.
Researchers found that progression - free survival (PFS) in patients receiving selumetinib was nearly 16 weeks and 50 percent of these patients
experienced tumor shrinkage, with 15 percent achieving major shrinkage.
Instead, Schlom says, «what we're seeing is increases in patient survival, as opposed to
tumor shrinkage.»
«The effective immune response didn't happen in every tumor model we tested, so we still need to figure out exactly what triggered
the tumor shrinkage and how to predict which tumors will shrink in response to virotherapy,» said Leddon, who is also working toward her medical and doctoral degrees at the University of Cincinnati.
Patients receiving temozolomide, the current standard chemotherapy, had seven weeks of PFS and
no tumor shrinkage.
Doctors at the University of Arizona Cancer Center at St. Joseph's Hospital and Medical Center in Phoenix reported today in Lancet Oncology that a new treatment for ovarian cancer can improve response rates (increase the rate of
tumor shrinkage) and prolong the time until cancers recur.
These findings provide further evidence of ONC201 as an inhibitor of cancer stem cells and support ongoing clinical trials in prostate cancer and glioblastoma that have shown evidence of
tumor shrinkage.
Mayo Clinic researchers have found that an experimental drug, LCL161, stimulates the immune system, leading to
tumor shrinkage in patients affected by multiple myeloma.
The results of the study indicate that the two therapies stimulated significant growth of HEVs in pancreatic and mammary tumors, leading to malignant cell death and
tumor shrinkage.
The NCI group saw
some tumor shrinkage in four others, they report online in Science 19 September.
NCI is establishing a national database to house and integrate genomic information from tumors with clinical response data (e.g.,
tumor shrinkage) and outcomes information (e.g., length of survival) as a resource for scientists, health care professionals, and patients.
What Ornish got, though, was an apparent reversal in cancer growth — the PSA didn't just rise slower, it trended down, which could be an indication of
tumor shrinkage.
>> the PSA didn't just rise slower, it trended down, which could be an indication of
tumor shrinkage.
Mitotane is often successful in controlling clinical signs and in some cases may also result in
tumor shrinkage.