Sentences with phrase «tumor shrinkage»

"Tumor shrinkage" refers to the reduction in size or volume of a tumor. It means that the tumor has become smaller, often as a result of medical treatment or intervention. Full definition
Piroxicam is a non-steroidal anti-inflammatory drug (also known as an NSAID) that has offered benefit both in alleviating symptoms due to inflammation in many dogs, as well as causing actual tumor shrinkage in some dogs.
Adding cisplatin to the standard gemcitabine / nab - paclitaxel drug treatment provided a very high rate of tumor shrinkage for patients with advanced pancreatic cancer, according to the results of a pilot clinical trial conducted by the HonorHealth Research Institute and the Translational Genomics Research Institute (TGen).
Pai notes cancer patients may see tumor shrinkage within the first three months on the ketogenic diet.
Trebananib does not increase the risks of hypertension (high blood pressure) and bowel perforation like bevaciuzmab, but still has a similar impact on tumor shrinkage and delaying cancer progression, research shows.
Of 10 men whose metastatic cancers could be measured with imaging scans, five experienced tumor shrinkage by more than half, including one man whose cancer completely disappeared.
Two patients with advanced infantile fibrosarcoma experienced sufficient tumor shrinkage with larotrectinib to allow for limb - sparing surgery with curative intent; both patients had negative margins after surgery, and they both remained progression - free without larotrectinib treatment after 4.8 and 6.0 months of follow - up.
Reuters reports that about 30 % of people treated with pembrolizumab experience significant tumor shrinkage.
Twentty - five percent of the patients had actual tumor shrinkage.
And using lower levels of Yervoy in combination with Opdivo actually prompted more tumor shrinkage, underscoring the fact that dosing is a critical and unpredictable factor for immunotherapies.
«In the past, we assumed a healthy immune system would fight off the virus infection before it could cause tumor shrinkage.
«In the tumor sample from a patient with high NRP - 1 expression, there was a significant improvement in the efficacy of the nanoparticle to induce tumor shrinkage,» said Nel.
Ultimately, of course, what matters isn't tumor shrinkage but patient survival.
The experimental device is being tested in cancer patients to see whether it can be tuned to accurately measure tumor shrinkage in response to therapy.
Responses are dramatic — you often have complete tumor shrinkage in a matter of weeks.
«We are looking to optimize the combinations of targeted therapies and the scheduling of those therapies so we can improve tumor shrinkage and minimize potential toxicities for a patient,» said Andrew Aplin, PhD, Associate Director for Basic Research and the Program Leader for Cancer Cell Biology and Signaling (CCBS) in the NCI - designated Sidney Kimmel Cancer Center at Jefferson Health.
«High rate of tumor shrinkage among pancreatic cancer patients.»
«We demonstrated that the co-administration of the iRGD peptide with the particles can enhance the effectiveness of pancreatic cancer treatment in the tumor model, leading to increased tumor shrinkage, disappearance of metastases and enhanced animal survival» said Meng, an adjunct assistant professor of nanomedicine.
Kidney cancer patients may see long - lasting tumor shrinkage with immunotherapy, which uses the immune system as a weapon to fight cancer.
In a phase 1 study, 80 % (28 out of 35) patients showed tumor shrinkage on scans.
«We treated these three patients with drugs that attack these genetic alterations and saw tumor shrinkage.
That is why researchers more often rely on faster - developing indicators of (apparently) improved health: tumor shrinkage in cancer, lowered blood - sugar levels in diabetes, reduced brain plaque in Alzheimer's, lowered bad cholesterol or elevated good cholesterol in heart disease.
The significant tumor shrinkage and immunologic changes observed support a complementary role of SBRT and PD - 1 immunotherapy, investigators concluded.
Trebananib does not increase the risks of hypertension (high blood pressure) and bowel perforation like bevaciuzmab, but still has a similar impact on tumor shrinkage and delaying cancer progression.
Researchers found that progression - free survival (PFS) in patients receiving selumetinib was nearly 16 weeks and 50 percent of these patients experienced tumor shrinkage, with 15 percent achieving major shrinkage.
Instead, Schlom says, «what we're seeing is increases in patient survival, as opposed to tumor shrinkage
«The effective immune response didn't happen in every tumor model we tested, so we still need to figure out exactly what triggered the tumor shrinkage and how to predict which tumors will shrink in response to virotherapy,» said Leddon, who is also working toward her medical and doctoral degrees at the University of Cincinnati.
Patients receiving temozolomide, the current standard chemotherapy, had seven weeks of PFS and no tumor shrinkage.
Doctors at the University of Arizona Cancer Center at St. Joseph's Hospital and Medical Center in Phoenix reported today in Lancet Oncology that a new treatment for ovarian cancer can improve response rates (increase the rate of tumor shrinkage) and prolong the time until cancers recur.
These findings provide further evidence of ONC201 as an inhibitor of cancer stem cells and support ongoing clinical trials in prostate cancer and glioblastoma that have shown evidence of tumor shrinkage.
Mayo Clinic researchers have found that an experimental drug, LCL161, stimulates the immune system, leading to tumor shrinkage in patients affected by multiple myeloma.
The results of the study indicate that the two therapies stimulated significant growth of HEVs in pancreatic and mammary tumors, leading to malignant cell death and tumor shrinkage.
The NCI group saw some tumor shrinkage in four others, they report online in Science 19 September.
NCI is establishing a national database to house and integrate genomic information from tumors with clinical response data (e.g., tumor shrinkage) and outcomes information (e.g., length of survival) as a resource for scientists, health care professionals, and patients.
What Ornish got, though, was an apparent reversal in cancer growth — the PSA didn't just rise slower, it trended down, which could be an indication of tumor shrinkage.
>> the PSA didn't just rise slower, it trended down, which could be an indication of tumor shrinkage.
Mitotane is often successful in controlling clinical signs and in some cases may also result in tumor shrinkage.
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