Sentences with phrase «tumor suppressors like»
«This function for BAI1 may have implications for cancer biology, since MDM2 can function as an oncogene by degrading important tumor suppressors like p53.»
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Inhibition of transcription (blockade of water) on tumor suppressor genes, such as p21, leads to cell transformation (growth of the cactus - like eremophytes instead of normal plants from the drought).
Genetic mutations that alter tumor suppressors such as the p53 gene are known to help tumors grow, and epigenetic modifications, too, can deactivate genes like this one.
Knudson's revolutionary two - hit theory of cancer formation enabled me to discover the first imprinted tumor suppressor gene, the Insulin like Growth Factor 2 Receptor (IGF2R), propelling me into the field of epigenetics.