However, tumor cells can circumvent this immune defense by establishing a surrounding microenvironment that prevents the infiltration of NK cells and thus
promotes tumor survival and growth.
Our scientists understand that cancer is a complex problem involving factors intrinsic to the tumor that drive its formation, together with tumor - extrinsic mechanisms — notably the vasculature and the immune system — that
enable tumor survival.
Nefedova studies molecular mechanisms by which bone marrow microenvironment
promotes tumor survival and progression.
ABL kinases are required
for tumor survival and tumor - induced osteolysis in the bone microenvironment.
«Taken together, these results support the hypothesis that multiple myeloma cells express bone - related genes in a Runx2 - dependent fashion that mimics bone marrow resident cells and likely contributes to
tumor survival and growth in the bone microenvironment,» Yang and colleagues wrote in the paper.
Fourth, vitamin C can inhibit tumor angiogenesis, the process of new blood - cell formation crucial to
tumor survival.