As part of our mission to improve the health and longevity of our Berners, the Berner - Garde Foundation (BGF) and Michigan State University (MSU), with support from the Bernese Mountain Dog Club of America (BMDCA), have established a Repository that collects, stores and maintains DNA and
tumor tissue samples from Bernese Mountain Dogs.
The researchers used
tumor tissue samples from melanoma patients to search for variations in their internal messaging.
Not exact matches
Researchers said the importance of collecting
tissue samples from recurrent
tumors will grow as more targeted therapies become available.
The investigators looked at 4,278
tumor samples from a
tissue repository of patients with GI tract cancers.
Analysis of blood and
tissue samples from one patient revealed that plakoglobin was expressed in CTC clusters but not single CTCs and also was expressed in some portions of both the primary
tumor and metastases.
From tissue and cell samples from five glioblastoma patients, the scientists obtained 33 individual cancer cells capable of reproduction, which grew into very different tumors in the
From tissue and cell
samples from five glioblastoma patients, the scientists obtained 33 individual cancer cells capable of reproduction, which grew into very different tumors in the
from five glioblastoma patients, the scientists obtained 33 individual cancer cells capable of reproduction, which grew into very different
tumors in the lab.
To streamline this process, Uhlén's team has created standardized arrays containing microscopic
samples from 48 kinds of normal human
tissue and 20 types of
tumors.
The researchers next will turn to analyzing the presence of myoferlin in
samples from numerous human
tumor types available in an Ohio State
tissue bank, which will allow them to compare protein levels in
tumors to clinical outcomes for the patients who provided the
samples.
For the study, researchers investigated
tissue samples from 297 people with brain
tumors.
They analyzed bacterial DNA found in breast
tissue samples from 58 women who were undergoing lumpectomies or mastectomies for either benign or cancerous
tumors, as well as
from 23 healthy women who had undergone breast reductions or enhancements.
The team chose to compare breast
tissue from healthy individuals with
tumor samples taken
from breast cancer patients — including both primary
tumors that had not spread
from the breast to other body sites, and highly aggressive, metastatic
tumors.
Investigators compared DNA
from the liquid blood biopsies to DNA
tissue samples from the
tumor, using mate - pair sequencing — an inexpensive whole exome sequencing that can reveal genetic changes that contribute to
tumor growth.
The researchers were able to replicate this finding by comparing the healthy thyroid
tissues in GTEx to 500
samples taken
from thyroid
tumors, compiled by The Cancer Genome Atlas, and giving support to the extensive impact of FOXE1 on cellular state.
The total environmental DNA of grape crown gall
tumor disease is revealed in the genetic profile based on 52
tissue samples of crown gall
tumor taken
from 16 grapevine species.
Overall, including all genomic variations present in most if not all
tumor cells (clonal) as well as those present only in subsets of the cancer cells (subclonal)
from tumor tissue, the researchers detected a total of 864 genetic changes in
tissue samples across the three
tumor types, and 627 (73 %) of those were also found in the blood.
To further validate our result in clinical
samples, we obtained primary
tumor from patients with advanced breast cancer and the
tissue was passaged once in nonobese diabetic / severe combined immunodeficient mouse without in vitro culture.
The researchers took healthy
tissue and
tumor samples from mice, and trained the nanoparticle - GFP sensors to recognize the bad cells, and for the GFP to fluoresce in the presence of metastatic
tissues.
To that end, Sharma gave an overview of MD Anderson's efforts to comprehensively characterize the activity of the immune cells in the patients they treat, and they've already analyzed over 42,000
tumor tissue samples,
from both before and after treatment, looking for clues regarding how treatment outcomes relate to immune cell infiltration into
tumors.
Tissue specimens were obtained from 30 cases having IDC and from 10 cases were diagnosed with benign breast lesions in addition to 10 normal breast samples were taken from tissue adjacent to the t
Tissue specimens were obtained
from 30 cases having IDC and
from 10 cases were diagnosed with benign breast lesions in addition to 10 normal breast
samples were taken
from tissue adjacent to the t
tissue adjacent to the
tumors.
Bottom Line: Bacterial load was significantly higher in pancreatic
tumor samples from patients with pancreatic ductal adenocarcinoma compared with pancreatic
tissue from normal individuals, and in studies using mice, eliminating certain «bad» bacteria slowed the growth of pancreatic cancer, reversed immune suppression, and upregulated the immune checkpoint protein PD1.
Tissue samples were obtained
from patients diagnosed with breast
tumor in the Department of Pathology, Medical Research Institute (MRI), Alexandria University, Egypt, during the period
from February to August 2015.
Tumor analyses commonly employ a correction with a matched normal (MN), a
sample from healthy
tissue of the same individual, in order to distinguish germline mutations
from somatic mutations.
Caris, under the guidance of Baker, provided the
tissue and ran the molecular profiling on solid
tumor samples collected
from across the United States.
Histopathology is the microscopic examination of specially prepared and stained
tissue sections
from the
tumor biopsy
sample.
The diagnosis is made based on history, x-rays of the bone and ultimately a biopsy, or removal of a
tissue sample from the
tumor.