Sentences with phrase «tumor types such»

The study published in Cancer Cell shows that exosomes from tumor cells of breast cancer (and other tumor types such as ovarian and endometrial) are different in size and composition than those of healthy cells.

Not exact matches

They analyzed patient factors such as age, stage at diagnosis, histologic type, Breslow thickness (a measurement of how deep the tumor is), and ulceration.

Most cancer vaccines developed to date have been designed to recognize and attack a specific known molecule — such as a cell - surface receptor — that is likely to be found on cancerous cells in any patient with that type of tumor.

If enacted, such a regulatory scheme could conceivably speed along clinical trials because it would allow investigators to draw from a large pool of people with diverse tumors that act along the same pathway instead of culling thousands of people with the same official cancer type.

«But mounting evidence confirming angiotropism and EVMM has revolutionized the knowledge of how cancer spreads through the body to the point that other scientists have confirmed the process in other solid tumor cell types such as pancreatic cancer.»

If such an indel is found in this gene, Ding and her colleagues suggest a patient may benefit from an EFGR inhibitor, such as erlotinib, regardless of the tumor type.

Some types of innate immune cells, such as natural killer cells, can actually protect against tumor growth.

However, such tumor cells display unusual antigens that are either inappropriate for the cell type or its environment, and can thus be recognized by the body's immune system.

Surprisingly, they found that although the patterns of gene expression — as shown by the RNA sequencing — differed between the hepatocellular carcinomas and the liver cancers with biliary phenotype and depended on the histological type, the overall pattern of mutations in the cells was actually similar between the tumors — of either type — that had emerged in patients who had had infections with either hepatitis C or B, and were different in patients without such infections.

Block or remove the estrogen with different types of drugs, such as the commonly prescribed tamoxifen or aromatase inhibitors, and the tumor stops growing.

PDGFRα is a cell surface tyrosine kinase receptor involved in organ development and tumor progression, it is present in multiple cell types such as mesenchymal cells, neurons, astrocytes, megakaryocytes and oligodendrocyte progenitor.

Answering important clinical questions — such as whether genetic diversity is a risk factor for aggressive tumor development or how it relates to treatment resistance — requires analyzing samples from many patients with different types of cancer.

They also showed that drugs against a type of breast tumor called HER2 positive breast cancer — such as the dual ERBB2 / EGFR inhibitor lapatinib — potentially could benefit more patients than currently receive them, if analysis of the tumor proteins is taken into consideration.

That genetic map led to key insights, such as the link between glioblastoma, the deadliest type of brain tumor, and a gene called BEX1.

The study further suggests that NSAIDs such as aspirin, ibuprofen and naproxen have a particularly advantageous effect when taken after diagnosis by colorectal, or CRC, patients without tumor mutation in the KRAS gene (KRAS wild - type tumors): The study shows that NSAID use by this group is associated with a survival benefit of 40 percent.

Researchers leading the largest genomic tumor profiling effort of its kind say such studies are technically feasible in a broad population of adult and pediatric patients with many different types of cancer, and that some patients can benefit by receiving precision drugs targeted to their tumors» mutations or being enrolled in clinical trials.

In further studies, they plan to explore the role of autophagy in immune reactions toward other tumor cell types, to determine whether such therapies might be effective in a broad range of cancers.

Checkpoint inhibitors such as ipilimumab, nivolumab and pembrolizumab have had a dramatic impact on treatment of several tumor types, including melanoma, lung cancer, head and neck cancers and others.

Now we want to extend this technology to animal models, such as cancer bearing mice, to verify its practical use in different types of tumors,» explains Park.

Bethesda, Md., Wed., May 1, 2013 - A comprehensive genomic analysis of nearly 400 endometrial tumors suggests that certain molecular characteristics - such as the frequency of mutations - could complement current pathology methods and help distinguish between principal types of endometrial tumors, as well as provide insights into potential treatment strategies.

Depending on characteristics such as how many tumor cells, blood vessel cells, and immune cells are touching each other, the tumor microenvironment can nearly triple the chance that a common type of breast cancer (estrogen - receptor positive / HER2 negative) that has reached the lymph nodes will also metastasize, Condeelis and colleagues showed in a 2014 study of 3,760 patients.

We need a new type of vaccine that uses select components of a microbe or tumor cell or other cause of disease, and administers these with other defined substances, such as adjuvants, that directly exploit immunology.»

Recent studies have described a subpopulation of cancer cells within tumors termed «cancer stem cells» (CSCs), which have stem - like properties such as self - renewal and the ability to differentiate into multiple cancer cell types [1 — 7].

The study conducted at SciLifeLab shows that temozolomide itself not only is cytotoxically active against glioblastoma tumors but also against other types of brain tumors, such as medulloblastoma and metastases from other primary tumors.

Recent studies have described a subpopulation of cancer stem cells (CSC) within tumors, which have stem - like properties such as self - renewal and the ability to differentiate into multiple cell types.

«The additional information we can now derive from tumor biomarkers such as E-cadherin, nm23 and microvessel counts should begin to allow us to tailor therapy according to individual tumor types,» added Samuel Hellman, MD, A.N. Pritzker Distinguished Service Professor of radiation and cellular oncology at the University of Chicago and co-author of the paper.

Because of their unique expertise in treating these types of tumors, our urologists can help identify and, when possible, avoid potential side effects — such as infertility, sexual dysfunction or incontinence — that may result from cancer treatment.

Recently, some other cytokines (such as tumor necrosis factor) or chemical drugs were also found to up - regulate several IFN - inducible gene family members (including RIG - G) through production of type I IFNs (37, 38), further indicating that the induction of RIG - G by ATRA in NB4 cells was tightly related with an IFNα autocrine pathway.

Moreover, the ever - growing catalogues of tumor genome sequences — such as those created by the Cancer Genome Atlas (TCGA) and the International Cancer Genome Consortium (ICGC)-- enable integrated analyses of germline variation with somatic mutation data across tumor types (i.e. pan-cancer analysis).

Morgridge computational biologist John Steill, another co-author of the KinderMining study, is using the KinderMiner tool to improve gene marker lists, which have numerous uses such as classifying cells or samples by cell type and identifying samples that may produce tumors.

The doctor reading your mammogram will be looking for different types of breast changes, such as small white spots called calcifications, lumps or tumors called masses, and other suspicious areas that could be signs of cancer.

«The types of cancer are very similar to those diagnosed in humans and similar cancers appear in both small animal species such as lymphoma and skin tumors.

While genetics and environmental factors can play a role in the disease's development, other variables such as toxins, radiation, and tumor viruses, as well as hormones can also be responsible for causing several types of cancer.

Complete removal of some types of tumors, such as sarcomas, can be difficult resulting in the tumor returning to the same area.

Indications for radiation therapy (RT) include the primary treatment of specific tumor types, such as nasal tumors and brain tumors, adjuvant treatment of incompletely excised tumors, and palliation to improve quality of life for patients with non-resectable or advanced cancers.

Relapse is not uncommon especially when dealing with certain types of tumors that are difficult to completely remove, such as sarcomas.

It is important to differentiate osteosarcoma from other tumor types and diseases that occur within bones, such as bacterial, viral, or fungal infections.

A CSF analysis («spinal tap») is sometimes performed to provide additional information such as identifying meningitis, infections or certain types of tumors.

This type of treatment shapes the radiation dose around the shape of the tumor with such precision that it leaves nearby structures (eyes, heart, etc.) unharmed, minimizing side effects.

Depending on the tumor type and location, your veterinarian may recommend adding other treatments such as chemotherapy.

This type of cancer has a high rate of metastasis, and imaging techniques, such as chest X-rays and abdominal ultrasounds, can help to determine if the tumors have spread to the lymph nodes or internal organs, such as the spleen or liver.

Tumors such as the case of several benign types of tumors which are referred to as being encapsulated, are candidates for a surgical appTumors such as the case of several benign types of tumors which are referred to as being encapsulated, are candidates for a surgical apptumors which are referred to as being encapsulated, are candidates for a surgical approach.

There are many different types of brain tumors, some act as space occupying lesions and other are functional such as pituitary tumors causing Cushing's disease.

Cancers in dogs, such as bone cancer, lymphoma and many other types of tumors, are almost identical to those same kinds found in humans and they tend to develop faster and run their course quicker, so it's an ideal way to see if a certain therapy will work.

There are several other more unusual tumor types that may be seen in this area such as the suprasellar germ cell tumor.

See below for information on specific types of cancer such as anal sac and colorectal tumors.

Depending on the tumor type and location, your veterinarian may recommend adding other treatments such as chemotherapy or radiation therapy.

Ferrets require good quality food and can be susceptible to a type of tumor, so it's a good idea to be prepared for care and veterinary expenses, just as you would for any other pet such as a dog or cat.

Canine glioma, an aggressive type of brain tumor, occurs most frequently in brachycephalic breeds (those with a broad, short skulls) such as Boxers and Boston terriers, although the tumors occur in other breeds, as well.

The insurance company will also want to know if the applicant has other health issues such as Alzheimer's disease or other types of memory loss / dementia, internal cancer (including a tumor or a cyst), emphysema, COPD, sleep apnea, dizziness, anxiety, arthritis, varicose veins, hernia, and / or any other disorder of the ears, eyes, throat, or nose.