Sentences with phrase «tumor volume of»

Treatment with the combination of MIA - 602 and doxorubicin led to an increase in final tumor volume of only 256.0 % (± 10.3 %).

The treatment with the combination of MIA - 602 and doxorubicin resulted in the smallest increase in tumor volume of 76.2 % (± 13.6 %).

Tumor volume of mice given doxorubicin increased by 201.6 % (± 7.1 %) and was also significantly (P < 0.001) reduced compared to controls.

Two tumors (4 %) had a partial response, defined as reduction in tumor volume of more than 30 percent.

In a mouse model of triple - negative breast cancer, mice injected with cancer cells that over-express ZMYND11 had tumor volumes of less than 50 cubic millimeters while control mice and those injected with cells expressing ZMYND11 deficient for binding to the methyl group had tumor volumes ranging from 150 to 400 cubic millimeters at eight weeks.

Sulforaphane, a putative anticarcinogen in broccoli, was provided orally to mice bearing androgen - insensitive human PC - 3 xenografts, and resulted in tumor volumes of 207 ± 35 and 90 ± 22 mm3 for the control and sulforaphane groups, respectively (22).

Not exact matches

«The minimum sample volume required is only 1 µL for analysis of 92 proteins, which has been proven to be a great advantage for applications with limited sample volumes, such as pediatric applications, fine - needle biopsies, and tumor microbiopsies,» he says.

EM: Imaging such as MRIs or CT scans, which reveal the mass and volume of the tumor, can fool you sometimes: The patient gets a scan, goes on a therapy, and when they return in a month for a second imaging, the structure and size of the tumor haven't changed.

He and his co-investigators analyzed 66 ultrasound images of tumors (32 pictures of a single tumor and 34 of multiple tumors) inside a plastic model of a breast to determine the augmented - reality system's accuracy of measuring tumor volume.

This study of 37 patients (24 men and 13 women, ages 51 to 80) who have never been treated with chemotherapy found direct correlation of the amount of cfDNA with tumor metabolism (based on PET - derived parameters), but not with metabolic tumor volume.

«These tumors are genetically very complex, and we demonstrated this by showing just the sheer volume of copy number changes, and that there are multiple clones in a single metastases tumor, and changes in metabolism that reflects the tumor's ability to adapt.»

When CCL5 is depleted, the infiltration of NK cells and the subsequent regression of tumor volume were no longer observed, thus confirming the crucial role of CCL5 in driving NK cells into autophagy - defective tumors.

«The traditional staging system does not account for the total volume of disease or baseline tumor burden,» Dr. Joseph says.

IP5 worked as well as cisplatin in reducing the volumes of the tumors, the team reports today in Cancer Research.

Quantification of cellular volume and sub-cellular density fluctuations: comparison of normal peripheral blood cells and circulating tumor cells identified in a breast cancer patient.

The animals were randomly divided into six groups of 20, when the tumor volume reached ~ 100mm3.

The mean volume values were recorded throughout the experiment and upon death or the last day of death the final measurement was included in our data for mean tumor volume measurement extraction.

Optical quantification of cellular mass, volume, and density of circulating tumor cells identified in an ovarian cancer patient.

And the volume of the tumors that did develop was 85 percent smaller.

The sum of metastatic tumor volume was first calculated from four lobes of lungs per animal (see Materials and methods), and the lung metastasis per group is presented as tumor volume (cubic millimeters).

It should be noted, however, that while a study on senescent cell ablation in genetically normal mice would provide at least some evidence on the effect of senescent cells (and their ablation) on promoting cancer, even such a study would likely show less effect than could be anticipated in a large mammal model, since even normally - aging mice rarely suffer metastatic disease to the extent of aging humans, as sheer primary tumor volume is generally sufficient to be fatal to mice.

The researchers therefore looked at possible indicators of tumor burden, including direct measurements such as lactate dehydrogenase and the number or volume of metastases, or indirect evidence such as leaving the primary tumor in place or if the goal of treatment was palliation.

The length and width of each nodule were measured with pixels and then converted to millimeters to calculate the tumor volume.

Metastatic tumor burden of each animal was calculated by combining tumor volumes from four lobes of lungs.

Working together with a multidisciplinary team of cancer specialists, our department uses highly advanced cancer care techniques including multimodality imagaing for defining tumor volume, state - of - the - art intensity modulated radiation therapy (IMRT), MRI - based treatment planning, and interstitial brachytherapy using high dosage rate treatment.

The combination of MIA - 602 and doxorubicin reduced the increase in tumor volume to 256 %.

Tumors were allowed to grow to a mean volume of 75 - 100 mm3 prior to administration of the initial treatment.

Control HCC1806 tumors grew by 435.3 % (± 41.6 %) of the initial tumor volume by week five, while tumors treated with MIA - 602 augmented by only 172.2 % (± 15.1 %), significantly (P < 0.001) less than controls.

Control MX - 1 tumors grew by 907.4 % (± 37.4 %) of the initial tumor volume by week five, but those treated with MIA - 602 increased by 434.8 % (± 12.9 %); significantly (P < 0.001) less than controls.

Not surprisingly, the growth of tumors treated with doxorubicin, which attained a volume 814.9 % (± 34.7 %) of the initial size, was not significantly different than controls.

Bennett EE, Angelov A, Vogelbaum MA, Barnett GH, Chao ST, Murphy ES, Yu JS, Suh JH, Jia XJ, Glen HJ, Ahluwalia MS, Mohammadi, The Prognostic Role of Tumor Volume in the Outcome of Patients with Single Brain Metastasis After Stereotactic Radiosurgery.

«Both total metabolic tumor volume (TMTV), computed on baseline PET, and end - of - induction PET (EOI PET) are imaging biomarkers showing promise for early risk stratification in patients with high tumor - burden follicular lymphoma,» reported lead author Anne Ségolène Cottereau, MD, from Cochin Hospital, René Descartes University, Paris, France, and colleagues.

Tumor volumes were measured on the indicated days after the administration of doxycyline.

The primary role of surgery is to biopsy and ascertain the diagnosis and, in some circumstances, there's a role for debulking or removal of a significant volume of tumor.

Extract of asparagus administered orally in doses of 250 and 500 mg / kg body weight for 10 days caused a significant reduction in tumor volume and tumor cell count.

He won the Nobel Prize for Literature in 1932 and died the following year of a brain tumor, leaving two final volumes of the Forsyte saga to be published posthumously.

Audi spent a couple of days in the hospital on supportive care after starting chemotherapy to help avoid side effects of tumor lysis, a syndrome that can occur and make the patient very ill when a large volume of tumor cells are rapidly killed by chemotherapy.

Clinical signs will vary depending on the stage of the disease, volume of tumor and anatomic location of the lymphoma.

In most of the cases, curative - intent radiation works best when the volume of the tumor has been reduced to a microscopic level.

No one has a shred of evidence that the volume of the product that was injected has anything to do with later tumor formation.

In one study of dogs with meningioma, the tumor's blood volume decreased by 21 % within 24 hours of beginning prednisone.

I give a patient chemotherapy an the tumor volume shrinks by 10 %, but I know the doubling time is 4 weeks, so after 3 and a half months I can claim I have killed 100 % of the tumor.

Accession high volume of solid tumor, and wet samples for The Department of Diagnostic Molecular Pathology Train / Mentor new hires to efficiently process laboratories samples, and transcribe clinical reports Process received Molecular orders to respective specialties within the Department of Pathology to review, and submit adequate material Actively assist in workflow modifications, and training manuals Transcribe clinical reports for all molecular tests in a timely manner Actively follow up with office assistants and clinicians within the institution to ensure proper paperwork / specimens are submitted for IMPACT testing.