Sentences with phrase «tumorigenesis results»
The central focus of my future work is to elucidate the mechanisms by which tumorigenesis results in the conversion of TGFβ from a suppressor of tumor formation to a promoter of tumor growth, invasion, and metastasis.
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HPV E6 binds with EDD1 to ubiquitinate TIP60, leading to the degradation of TIP60, eventually resulting in tumor tumorigenesis.
«Our results suggest that intentional body weight loss by diet manipulation does not provide any beneficial effects on colon tumorigenesis and it may in fact aggravate liver capacity of repair.»
These results suggested that the expression of mutated BRAF and GRM1 is critical in the determination of future tumorigenesis.
These results reveal that aneuploidy induced by transient centrosome amplification can accelerate tumorigenesis in p53 - deficient cells.
These results also suggest a direct role for unphosphorylated STAT6 in tumorigenesis.
TGFβ inhibits tumor initiation and progression by inducing cell cycle arrest and apoptosis; however epithelial tumorigenesis may escape this common antitumor mechanism by inducing aberrations in TGFβ signaling resulting in enhanced development and progression of human carcinomas.
Estrogens are known for their proliferative effects on estrogen - sensitive tissues resulting in tumorigenesis.