The Transcription Factor ZFX Is Required for Maintaining
the Tumorigenic Potential of Glioblastoma Stem Cells.
These JAK1 mutations provide cells with
tumorigenic potential by inducing constitutive activation of the JAK - STAT pathway, which supports their autonomous proliferation.
FDA's position on assessment of
tumorigenic potential of cell products for regenerative medicine
In breast cancer, miR - 7 was shown to block invasiveness and
tumorigenic potential by targeting PAK, which is consistent with the idea of tumor suppressor function of miR - 7 (25).
In SA2 - deficient Ewing sarcoma and bladder cancer, further depletion of SA1 profoundly and specifically suppressed cancer cell proliferation, survival and
tumorigenic potential.
Not exact matches
Our lab is focused on delineating the mechanisms underlying these key GSC
tumorigenic properties with a long - term goal of uncovering
potential therapeutic targets.