Sentences with word «tumorigenicity»

It was indeed found DAXX promotes the in vivo tumorigenicity of two human PCa cell lines in a subcutaneous tumor xenograft model via suppression of autophagy [Submitted].

Astonishingly, the same mechanism that drives the mesenchymal GSC tumorigenicity in humans acts in an evolutionarily distant organism, the fruit fly.

BME has also been employed in cell attachment, neurite outgrowth, angiogenesis assays, in vitro cell invasion and in vivo tumorigenicity assays.

Increased transforming growth factor beta expression inhibits cell proliferation in vitro, yet increases tumorigenicity and tumor growth of Meth A sarcoma cells.

One rare KRAS allele, D33E, displayed tumorigenicity and constitutive activation of known RAS effector pathways.

Man J, Shoemake S, Zhou W, Fang X, Wu Q, Rizzo A, Prayson R, Bao S, Rich JN, Yu JS, Sema3C Promotes The Survival and Tumorigenicity of Glioma Stem Cells Through Rac1 Activation.

Researchers have demonstrated that the enzymatic activity of R5 receptor - type protein tyrosine phosphatases is a requisite for the maintenance of stem cell properties and tumorigenicity in glioblastoma cells and could be a promising drug target for treatment.

However, viral integration into the host genome increases the risk of tumorigenicity.

Small numbers of glioma stem - like cells, or GSCs, drive the tumorigenicity of GBM and thus are prime targets for possible treatments.

On the contrary, the expression level of KLF4 was downregulated in the gastrointestinal cancer due to the promoter methylation, and overexpression of this gene was shown to attenuate the tumorigenicity of colonic and gastric cancer cells in vivo (31, 32).

«It will be necessary to characterize the cells in more detail... for their tumorigenicity upon transplantation,» he wrote in an email.

RASSF1A overexpression reduces in vitro colony formation and the tumorigenicity of cancer cell lines in vivo.

First academic GLP center for performing biodistribution, toxicology / tumorigenicity and validation studies on gene and cell therapy products.

Pharmacological targeting of guanosine monophosphate synthase suppresses melanoma cell invasion and tumorigenicity.

Thank you for sending your work entitled «miR - 142 regulates the tumorigenicity of human breast cancer stem cells through the canonical WNT signaling pathway» for consideration at eLife.

Chang, RL, Hùang, MT; Wood, AW; Wong, CQ; Newmark, HL; Yagi H; Sayer, JM; Conney, AH: Effect of ellagic acid and hydroxylated flavonoids on the tumorigenicity of benzo (a) pyrene and -LRB-»)-78 ß,8a - dihydroxy - 9a, 10 a - epoxy -7,8,9,10-tetrahydrobenzo (a) pyrene on mouse skin and in the newborn mouse.