After a median follow - up of 22 months, the team found that the drugs were safe and shrank
tumors in a subset of patients, with an overall response rate of 27 percent, which included complete responses in two patients and partial responses in four patients.
Not exact matches
If hypofractionated radiation with curative intent can reduce the treatment time for lung cancer
patients by half with no greater toxicity, and with equivalent — if not better —
tumor control and survival outcomes, this research could result
in a change
in the paradigm
of how a large
subset of locally advanced NSCLC
patients are treated.»
For the
subset of more recent
patients, the researchers assessed
tumor cell behavior —
in particular, cancer cells» ability to cross the endothelium (inner layer)
of blood vessels.
Therapies that prevent
tumor blood vessel growth are often used
in clinics to fight cancer — but they are only effective
in a particular
subset of patients.
The fusion
of these two genes was observed
in just three percent
of tumors studied, so any therapy based on this particular genetic aberration would apply to only a small
subset of glioblastoma
patients.
Modeling mRNA expression heterogeneity
in tumors through bimodal profiles is a novel powerful approach with the potential to uncover therapeutic targets that benefit
subsets of cancer
patients.