Sentences with phrase «tumors of the central nervous system»

In a second study, described online Oct. 14 in Modern Pathology, the Johns Hopkins investigators sought a genetic source that could accurately identify subsets of low - grade pediatric gliomas, the most frequent tumors of the central nervous system in children.

Scientists have substantially enhanced the classification of tumors of the central nervous system.

Researchers at the University of Chicago noted that in recent years, genetically engineered herpes simplex virus studied for its efficacy against malignant tumors of the central nervous system and the liver was blocking certain types of cell death and proliferation of surviving cells.

One such example is a rare, aggressive childhood brain tumor called primitive neuroectodermal tumor of the central nervous system (CNS - PNET).

I then transitioned to a dedicated surgical neuro - oncology fellowship at the University of Miami, where I gained significant experience in treating malignant brain tumors, developing clinical trials, and delivering minimally invasive therapies for both primary and metastatic tumors of the central nervous system.

Not exact matches

Treatment with an investigational CAR T - cell therapy induced complete remission of a brain metastasis of the difficult - to - treat tumor diffuse large - B - cell lymphoma (DLBCL), which had become resistant to chemotherapy — the first report of a response to CAR T - cells in a central nervous system lymphoma.

In a study published in the Journal of NeuroOncology, TGen researchers report that PPF works to limit the spread of glioblastoma multiforme, or GBM — the most common primary tumor of the brain and central nervous system — by targeting a protein called TROY.

It normally takes a long time for the rabies virus to traverse the central nervous system, whereas Youn's nanoparticles made it to tumor cells in a matter of hours.

To be able to treat cancer of the central nervous system (CNS) successfully, it is important to have very precise knowledge about the molecular characteristics of the tumors in order to «give them the right name.»

About 22,000 new cases of brain and central nervous system (CNS) tumors are diagnosed each year in the United States, and 3,000 of those are in children.

Inclusion Criteria: • Availability of tumor tissue for mesothelin expression testing • Histologically - confirmed, mesothelin - expressing metastatic or advanced non-metastatic disease (tumour type specific inclusion criteria) • At least one measurable lesion according to either Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 or International Thymic Malignancy Interest Group (ITMIG) modified RECIST 1.1 as applicable • Adequate bone marrow, liver, renal and coagulation function • Left ventricular ejection fraction (LVEF) ≥ 50 % of the lower limit of normal (LLN) according to local institutional ranges • Eastern Cooperative Oncology Group (ECOG) 0 or 1 Exclusion Criteria: • More than one prior anti - tubulin / microtubule agent • Corneal epitheliopathy or any eye disorder that may predispose the patients to this condition • Symptomatic Central nervous system (CNS) metastases and / or carcinomatous meningitis • Contraindication to both CT and MRI contrast agents • Active hepatitis B or C infection • Pregnant or breast - feeding patients • Tumor type specific exclusion critumor tissue for mesothelin expression testing • Histologically - confirmed, mesothelin - expressing metastatic or advanced non-metastatic disease (tumour type specific inclusion criteria) • At least one measurable lesion according to either Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 or International Thymic Malignancy Interest Group (ITMIG) modified RECIST 1.1 as applicable • Adequate bone marrow, liver, renal and coagulation function • Left ventricular ejection fraction (LVEF) ≥ 50 % of the lower limit of normal (LLN) according to local institutional ranges • Eastern Cooperative Oncology Group (ECOG) 0 or 1 Exclusion Criteria: • More than one prior anti - tubulin / microtubule agent • Corneal epitheliopathy or any eye disorder that may predispose the patients to this condition • Symptomatic Central nervous system (CNS) metastases and / or carcinomatous meningitis • Contraindication to both CT and MRI contrast agents • Active hepatitis B or C infection • Pregnant or breast - feeding patients • Tumor type specific exclusion criTumor type specific exclusion criteria

Thanks to refined surgical techniques and improved chemotherapy and radiation therapy, the majority of children with brain and spinal cord tumors — collectively known as central nervous system tumors — are now long - term survivors.

However, some testicular tumors can grow aggressively and metastasize (spread) to other parts of the body, most commonly to the lymph nodes, lungs, liver and central nervous system, including the brain and spinal cord.

It's an important amino acid in Phase II liver detoxification, is crucial in maintaining healthy function of the central nervous system, helps to regulate the synthesis of bile acids, and is thought to promote wound healing and inhibit tumors.

Diffuse intrinsic pontine gliomas account for 10 percent of all childhood central nervous system tumors.

Brain disease, such as a tumor or stroke, that damages the auditory nerve or other parts of the central nervous system that control hearing can also affect hearing.

Critical illness (ANICO has one of the most generous lists): heart attack, stroke, invasive cancer, end stage renal failure, major organ transplant, ALS, blindness, paralysis, arterial aneurysms, central nervous system tumors, major multi-system trauma, AIDS, severe disease of major organ, severe central nervous system disease, major burns, loss of limbs

Patients were diagnosed with various types of cancer, including breast (54 %), gynecological (11 %), skin (9 %), hematological (8 %), urological (5 %), soft tissue and bone tumors (5 %), head / neck (3 %), gastrointestinal (3 %) and central nervous system (2 %).