Sentences with phrase «tumour cell growth»

In a study done by scientists at Canada's British Columbia Cancer Research Centre, it was found that mice fed on a high - protein, low - carbohydrate diet had slower tumour cell growth than those fed a typical Western diet high in carbohydrates.

Not exact matches

The hydra tumour cells were shown to be invasive: if introduced into a healthy organism, they can trigger tumour growth there.

Although these spots themselves are harmless, if some of the spots are bigger than a 50 cent coin, then it could be due to Neurofibromatosis (NF), which is a genetic disorder of the nervous system that causes abnormal cell growth of nerve tissues or benign tumours to form on the nerves anywhere in the body at any time.

PTEN is known as a tumour suppressor gene meaning that it typically slows the growth of cells and its loss can lead to cancer.

A woman in the US has developed a tumour - like growth near her spine eight years after a failed stem cell treatment to cure her paralysis

That now appears to be because they prompt the growth of the very tumour cells they are meant to kill.

They conclude that the sperm made by these cells contained the disease - linked mutations and that the mutations may be driving the growth of the tumours (Nature Genetics, DOI: 10.1038 / ng.470).

These «aggregates» can comprise hundreds of thousands of cells, be up to 2 mm in diameter and be eight times more resistant to chemotherapy drugs — firstly because hypoxic conditions are created inside the aggregates and secondly because these tumour cells reduce growth and are therefore less sensitive.

But as inflammation is known to promote the growth of cancer, they assumed that the cells were helping the tumours to grow.

Only cancer cells that received these growth factors switched on this pathway, and only they could seed new tumours when injected into mice.

When chlorotoxin is tagged with a fluorescent dye, it will illuminate a tumour — a trick that makes the surgeon's job easier by helping to pinpoint cancerous growth and ensure that all the cancerous cells are removed and healthy tissue spared.

The researchers hope that ultimately human trials will prove the efficacy of the OH14 compound in sensitising tumour cells and cancer stem cells to existing drug - based therapies thus disabling tumours from seeding new growth after treatment.

«In most cases we think the body's growth control mechanisms eventually stop the cells from proliferating further, but in occasional cases where additional mutations occur in the clump of cells, a tumour will eventually develop,» says Andrew Wilkie also of the University of Oxford, who supervised the work.

They concluded that the sperm made by these cells contained the disease - containing mutations and that the mutations may be driving the growth of the tumours.

A woman in the US has developed a tumour - like growth eight years after a stem cell treatment to cure her paralysis failed.

There is a growing number of lawsuits against such clinics and a few cases have been reported of tumours or excessive tissue growth (see «Ongoing stem cell trials» below).

Infected individuals however, are constantly exposed to granulin - like proteins secreted by flukes, which subsequently cause host cells to proliferate uncontrollably, leading to tumour growth.

«Shutting off vital tumour growth processes can lead to the death of human brain tumour - initiating cells.

The result is increased cell growth, also referred to as compensatory proliferation, which can lead to tumour development.

Cancer stem cells are strongly associated with the growth and recurrence of all cancers and are especially difficult to eradicate with normal treatment, which also leads to tumours developing resistance to other types of therapy.

Such a drug would block only the androgen receptor in prostate cells, and so stop the chain of reactions leading to further tumour growth, says McCague.

The experimental drug cediranib blocks the cell surface receptor VEGF, which stimulates the growth of new blood vessels to feed the growth of tumours,» explains study researcher Dr Paul Symonds, of the Department Cancer Studies & Molecular Medicine at the University of Leicester, UK.

Samples of tumours from bowel cancer patients given different doses of resveratrol showed that even lower doses can get into cancer cells and potentially affect processes involved in tumour growth.

Therefore, researchers from the CNIO's Experimental Oncology Group have focused their work on identifying a stromal cell population that fosters tumour growth, to later discover why they have this capacity and reverse it.

For example, if your topic is a gene that controls cancer cells, a description of sinister tumour growth in the relevant organ will probably do the trick.

A team working at the Institute of Cancer Research and the Royal Marsden Hospital in London, in collaboration with scientists at the National Cancer Institute in Bethesda, Maryland, has found that tamoxifen also works by encouraging the cells surrounding a tumour to produce a «growth factor».

Cancer stem cells, which fuel the growth of fatal tumours, can be knocked out by a one - two combination of antibiotics and Vitamin C in a new experimental strategy, published by researchers at the University of Salford, UK.

«We have identified a number of pharmaceutical compounds that selectively inhibit — in different experimental models — the mitochondrial enzyme responsible for the tumour growth, thus limiting fat synthesis and without harming normal cells.»

Olaparib stopped prostate cancer growth, generating falls in prostate specific antigen (PSA) levels, falls in circulating tumour cell counts in the blood, and radiological responses on CT scans and MRI.

They found that the drug increased the level of lactate in cells and, more importantly, reduced tumour growth.

The virus, code - named JX - 954, targets two genes involved in cancer cell growth and blood supply, which show increased activity in tumours.

Scientists have identified for the first time the «cell of origin» — in other words, the first cell from which the cancer grows — in basal cell carcinoma, the most common form of skin cancer, and followed the chain of events that lead to the growth of these invasive tumours.

In the future, scientists hope to target stem - cell - like cells within cancers that may be responsible for most of the growth of some tumours, and evade existing drugs.

Tamoxifen prevents oestrogen from stimulating growth of breast cancer cells but some tumours can eventually develop resistance to the treatment, making the drug ineffective.

We target tumours by exploring how the proteins found on the cancer cell surface can be utilised to inhibit growth or kill tumours.

For analysis of tumour growth over time, 1 × 106 B16F10 luciferase - positive cells were injected s.c. into the right flank of mice.

In tumour cells, the signals controlling cell growth and survival are dysfunctional, thus enabling the cells to grow in an uncontrolled manner.

«I originally trained as a developmental biologist, then, during my postdoc in stem cell biology, I became interested in research showing that the growth of brain tumours might be driven by cells similar to neural stem cells.

Stem cells and their tumorigenic alter egos cancer stem cells (CSCs) share many key properties, although CSCs are also posited to promote tumour growth, evolution, and drug resistance [1].

Tumour cells are «glutamine - addicted» [1,2] because glutamine is coupled to mechanistic target of rapamycin (mTOR) signalling, which integrates signals from growth factors, energy status and amino acid nutrition and co-ordinates these signals with cell growth, cell cycle progression and antioxidant machinery [3].

The adenomatous polyposis coli (APC) gene is a tumour suppressor gene, i.e. a gene preventing uncontrolled cell growth that could lead to the formation of a cancer tumour.

The stem cell theory of cancer hypothesizes that «stem - like» cancer cells are responsible for the generation of tumours and for sustaining tumour growth (reviewed in ref.17).

Research has discovered that a compound in parsley could prevent the growth of specific breast cancer tumour cells.

Green tea contains a rich concentration of flavonoids and polyphenols, natural antioxidants that may protect cells from carcinogens (cancer - causing substances) and inhibit tumour growth by helping to neutralise free radicals in the body.

Another ingredient richly available in oat is inositol hexaphosphate (phytic acid), a strong antioxidant, particularly known to enhance natural killer cell activity and to suppress tumour growth.

For example, glycine, amongst several other amino acids, is particularly useful for promoting cell growth: ideal in a baby, but not welcome in a cancerous tumour.

The same thing happens (the inhibition of stated growth factors) with hyperbaric oxygen therapy so it makes sense how all this fits together in powerful synergy to increase metabolic stress on tumour cells.

Fasting cycles retard growth of tumours and sensitise a range of cancer cell types to chemotherapy http://stm.sciencemag.org/content/scitransmed/4/124/124ra27.full

The Journal of Agricultural and Food Chemistry had on its December 2006 issue a report that found the ability of red raspberries to repress the human oral and breast, as well as colon and prostate tumour cell lines growths when they were tested in test tubes.

· Cancer Growth and Spread — Healing Angiogenesis and Metastasis, discussing blood vessel development and growth factors, dysregulation including hypoxia and other blood supply stress responses in cancer and other diseases and how cancer cells travel and invade — metastasis via the complex tumour microenvironment — TME — comprised of immune cells, cytokines, growth factors, reactive oxygen species (ROS) and cancer - associated fibroblast Growth and Spread — Healing Angiogenesis and Metastasis, discussing blood vessel development and growth factors, dysregulation including hypoxia and other blood supply stress responses in cancer and other diseases and how cancer cells travel and invade — metastasis via the complex tumour microenvironment — TME — comprised of immune cells, cytokines, growth factors, reactive oxygen species (ROS) and cancer - associated fibroblast growth factors, dysregulation including hypoxia and other blood supply stress responses in cancer and other diseases and how cancer cells travel and invade — metastasis via the complex tumour microenvironment — TME — comprised of immune cells, cytokines, growth factors, reactive oxygen species (ROS) and cancer - associated fibroblast growth factors, reactive oxygen species (ROS) and cancer - associated fibroblast (CAF);