The Journal of Agricultural and Food Chemistry had on its December 2006 issue a report that found the ability of red raspberries to repress the human oral and breast, as well as colon and prostate
tumour cell lines growths when they were tested in test tubes.
To do this, they switched from using dead tumour cell samples to patient - derived
tumour cell lines, in which fresh samples of a person's tumour are grafted onto mice and grown to the required volumes.
The team is already testing the drugs in
the tumour cell lines it created.
Putting together their analyses of the mitochondrial DNA in
each tumour cell line and the metabolic pathways at work, the team were able to deduce how each cell line's genetics directly affected its ability to multiply.
Not exact matches
Cell lines from human
tumours did exist, but were considered unsafe: what if cancerous
cells were transferred along with the vaccine?
Breast cancer researchers have mapped early genetic alterations in normal - looking
cells at various distances from primary
tumours to show how changes along the
lining of mammary ducts can lead to disease.
The team used five types of antibiotics — including one used to treat acne (doxycycline)-- on
cell lines of eight different types of
tumour and found that four of them eradicated the cancer stem
cells in every test.
In lab experiments, the research team used
cell lines derived from 40 patient
tumour samples to identify that CD151 contributes to the survival of
cells of high - grade serous ovarian cancer origin.
Cells lining the blood vessels send chemical signals, called cytokines, to the
tumour to help it resist DNA damage and to recover.
Initially, the Geneva researchers observed the vascularisation processes of human
tumour cells from different
cell lines.
Experimental models include yeast, mammalian and human
cell lines, mutant mouse models and
tumour samples.
On the basis of studies on the XMRV - producing human prostate cancer
cell lines CWR22Rν1 and CWR - R1 and their progenitor
tumour xenograft CRW22, they concluded that XMRV infections were caused by contamination during in vivo passaging in nude mice.
Some receptors display a broad pattern of expression across
tumour types, while others were expressed in
cell lines from a particular tissue.
Most cases of breast cancer in dogs (approximately 76 percent) are adenocarcinomas, or
tumours that develop in the dog's breast duct
cell linings.