Sentences with phrase «tumour cell survival»

The GCN2 - ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation

Not exact matches

But traps to mop up tumour cells as they infiltrate the body can boost chances of survival

The five year disease - free and overall survival rates for patients with high - risk malignant germ cell tumours remains less than 50 %, and so accurate diagnosis and monitoring is crucial to improving outcomes for patients.

In lab experiments, the research team used cell lines derived from 40 patient tumour samples to identify that CD151 contributes to the survival of cells of high - grade serous ovarian cancer origin.

Cancer tumours manipulate a natural cell process to promote their survival suggesting that controlling this mechanism could stop progress of the disease, according to new research led by the University of Oxford.

In the mice, the neuron - like cells did not grow as quickly as the original cancer cells, and analyses of the tumour tissue from patients show that those with a high level of the estrogen receptor have a better survival rate that those with a low.

By understanding the survival factors that keep cancer cells alive we aim to develop new and effective drugs that can activate natural cell death or inhibit impaired survival mechanisms in tumour cells.

In tumour cells, the signals controlling cell growth and survival are dysfunctional, thus enabling the cells to grow in an uncontrolled manner.

Areas of focus include: understanding how tumour - reactive T cells and B cells promote patient survival in cancer; defining the effects of standard treatments on tumor immunity; and using genomic approaches to identify novel tumour mutations that can serve as target antigens for immunotherapy.