Sentences with phrase «tumour cells from patients»

The team is currently working on genome sequencing of individual circulating tumour cells from patients at the Vancouver Prostate Centre.

«With this breakthrough it is possible to generate cell models with the same alterations as observed in tumour cells from patients, which will allow us to study their role in tumour development,» says CNIO researcher Sandra Rodríguez - Perales.

One method is to remove some tumour cells from the patient at the time of surgery, insert a gene for an immune - stimulating protein into them, and return them to the body.

Not exact matches

These were released into tumour cells that had been taken from glioblastoma patients and grown in the lab.

The time needed for breast cancer metastases (secondary lesions caused by cells that have escaped from the original tumour) to develop varies between patients, and little is known about the mechanisms that govern latency (the dormant state of cells that have already spread through the body).

Growing mini tumours in the lab from a patient's own cells could help doctors discover the best way to treat each person, homing in on the right drugs to use

The research team with international collaborators analysed more than 100 patient samples from ovarian and other cancer types to discover a distinct population of cells found in some tumours.

The team worked on tissue from three patients with colorectal cancer, taking normal bowel stem cells and cells from four different areas of the tumours.

Samples of tumours from bowel cancer patients given different doses of resveratrol showed that even lower doses can get into cancer cells and potentially affect processes involved in tumour growth.

To do this, they switched from using dead tumour cell samples to patient - derived tumour cell lines, in which fresh samples of a person's tumour are grafted onto mice and grown to the required volumes.

In lab experiments, the research team used cell lines derived from 40 patient tumour samples to identify that CD151 contributes to the survival of cells of high - grade serous ovarian cancer origin.

In collaboration with Dr Gabriele Bonatz from the Augusta clinics in Bochum (Brustzentrum), Hatt's team confirmed the existence of TRPV1 in tumour cells in nine different samples from patients suffering from breast cancer.

In the mice, the neuron - like cells did not grow as quickly as the original cancer cells, and analyses of the tumour tissue from patients show that those with a high level of the estrogen receptor have a better survival rate that those with a low.

The researchers studied tumour tissue from patients, cultivated human tumour cells and tumours in mouse models for neuroblastoma.

Studies have shown that lymphocytes isolated from a patient's tumour are often specifically programmed to kill that patient's cancer cells.

Carried out in cells in the laboratory, in mice and in samples from patients» tumours, the researchers showed this «safe haven» lets melanoma cells turn on a parallel set of cell signals that helps them survive.

Directly derived from patient tumours without any genetic manipulation, these new products provide the assurance of primary cells with long - term reproducibility and scalability

In the genome of tumour cells of 11 patients, the scientists observed the insertion of a viral DNA segment from adeno - associated virus type 2, known as AAV2.

We are investigating how tumour cells can disseminate from the primary tumour and remain alive but clinically undetectable for many years, and how they start expanding into life threatening cancers in some patients.

Targeting CTCs, the cells responsible for spreading cancer, is important because they carry information from the primary tumour that can inform treatment; however, they are outnumbered by a billion - to - one by normal cells in a patient» blood and are therefore extremely challenging to capture.