The team plans to test the approach in a clinical trial in which chemotherapy drug selection for each person will be guided by testing balls of
their tumour cells in the lab.
Using
tumour cells in the lab, as well as mini lab - grown tumours called organoids, Coleman hopes to reveal more about the role these faulty molecules — called protein «hydroxylases» — have in cancer.
Not exact matches
These were released into
tumour cells that had been taken from glioblastoma patients and grown
in the
lab.
A COMPOUND that slows the proliferation of triple - negative breast cancer
cells in lab tests could lead to the first drugs to target this aggressive type of
tumour.
One approach would be to identify immune
cells in a
tumour, grow them
in a
lab, and then infuse them back into the patient — a technique called adoptive
cell transfer.
Growing mini
tumours in the
lab from a patient's own
cells could help doctors discover the best way to treat each person, homing
in on the right drugs to use
In lab experiments, the research team used
cell lines derived from 40 patient
tumour samples to identify that CD151 contributes to the survival of
cells of high - grade serous ovarian cancer origin.
The existence of cancer stem
cells has already been reported
in a number of human cancers, explains Professor Jacobsen, but previous findings have remained controversial since the
lab tests used to establish the identity of cancer stem
cells have been shown to be unreliable and,
in any case, do not reflect the «real situation»
in an intact
tumour in a patient.
I have a 3 yr old choco
lab who has had 5 mast
cell tumours removed
in the past 11 months.