Not exact matches
Reporting their
laboratory findings
in the journal Aging, the team observed that addition of DPI to a mixed population of
cells eliminated the
tumour initiating cancer stem
cells.
Carried out
in cells in the
laboratory,
in mice and
in samples from patients»
tumours, the researchers showed this «safe haven» lets melanoma
cells turn on a parallel set of
cell signals that helps them survive.
Our
laboratory is interested
in exploring the molecular mechanisms that drive the production of cancer stem
cells and specifically
in dissecting the microRNA / transcription factor circuitry that connects such differentiation metastability to
tumour aggressiveness.
After a post-doctoral experience
in The Jackson
Laboratory in Maine, USA he returned to Italy to pursue a scientific career
in tumour cell biology, during which he published his work
in prestigious scientific journals with the support of several funding agencies including the European Community, Associazione Italiana Ricerca sul Cancro (AIRC) and the Italian Ministry for Health.