Sentences with phrase «tumour development with»
Their experiments in pre-clinical models proved to be successful, confirming lower tumour development with the regulation of the proteins that affect production of VLDL (precursors of LDL) and uptake of LDL by receptors from the liver.
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The Lund University research team has looked at how cancer cells communicate with surrounding cells and how this encourages the development of malignant tumours.
«With this breakthrough it is possible to generate cell models with the same alterations as observed in tumour cells from patients, which will allow us to study their role in tumour development,» says CNIO researcher Sandra Rodríguez - PeraWith this breakthrough it is possible to generate cell models with the same alterations as observed in tumour cells from patients, which will allow us to study their role in tumour development,» says CNIO researcher Sandra Rodríguez - Perawith the same alterations as observed in tumour cells from patients, which will allow us to study their role in tumour development,» says CNIO researcher Sandra Rodríguez - Perales.
Peng Loh of the National Institute of Child Health and Human Development in Bethesda, Maryland, and colleagues studied tumours from 99 people with liver cancer.
The largest - ever study to sequence the whole genomes of breast cancers has uncovered five new genes associated with the disease and 13 new mutational signatures that influence tumour development.
Professor Geoff Pilkington, study co-author and Head of the Brain Tumour Research Centre, said: «Although this work is still at an early stage, we have demonstrated key elements that are associated with tumour cell binding to blood vessels and this may provide a target for future drug development to prevent the development of secondary tumours in the Tumour Research Centre, said: «Although this work is still at an early stage, we have demonstrated key elements that are associated with tumour cell binding to blood vessels and this may provide a target for future drug development to prevent the development of secondary tumours in the tumour cell binding to blood vessels and this may provide a target for future drug development to prevent the development of secondary tumours in the brain.
The discovery could help with future development of novel treatments to prevent metastasis and secondary tumours.
It could also lead to the development of new breast cancer drugs to target tumours with a specific genetic make - up.
Noor talked to us about moving to the UK, developing her research on brain tumours, and building her research group with a CRUK Career Development Fellowship.
Mutations in p53, BRCA1 and chromosome instability are frequently associated with ovarian tumour development, but little is know about the cytoskeleton organisation in this type of tumours.
However, when crossed with PyMT - Tg mice or MMTV / Neu (mouse mammary tumour virus promoter - Neu)- Tg mice, the development and progression of breast cancer were markedly decreased on Slc6a14 − / − background.
In contrast, no Slc6a14 − / − female with PyMT transgene developed tumours at 3 months of age; however, at 4 months of age, small tumour nodules became detectable (Figure 2B), indicating a marked delay in mammary tumour development in PyMT - Tg mice as a consequence of Slc6a14 deletion.