"Tumour growth" refers to the increase in size or spread of an abnormal mass of cells called a tumor in the body.
Full definition
But this is the first time scientists have been able to show the role the altered gene plays in
tumour growth in the prostate.
Philadelphia, PA (Scicasts)-- Angiogenesis, the formation of new blood vessels, is essential
for tumour growth.
The research comes from the team that discovered how the main psychoactive ingredient in cannabis, known as THC,
reduces tumour growth in cancer patients.
When gut microbes were transplanted from this group to the other group it
slowed tumour growth by almost the same extent as treatment with an anti-cancer drug currently being trialled in humans.
Green tea contains a rich concentration of flavonoids and polyphenols, natural antioxidants that may protect cells from carcinogens (cancer - causing substances) and
inhibit tumour growth by helping to neutralise free radicals in the body.
They have discovered that the Saa3 gene is at least one of the genes responsible for the property that
fosters tumour growth in these cells.»
They showed that blocking the microRNA
stopped tumour growth in bowel cancer mouse models, and in half of them tumours regressed so dramatically they could no longer be seen by imaging.
In their conclusions the researchers decided that appropriate L - glutamine supplementation can considerably improve the metabolism and entire clinical state of cancer patients without
increasing tumour growth.
Radiation techniques were subsequently developed for use after surgery to control
small tumour growths.
«Over 40 % of prostate cancers lose PTEN and some lose both PTEN and another tumour suppressor gene, INPP4B, but we didn't previously have a clear picture of how this
affects tumour growth,» says IMED Biotech Unit scientist Sabina Cosulich, at AstraZeneca.
Tumours in these mice grew 50 per cent more slowly than those in healthy mice, indicating that one extra copy of the gene has a significant effect
on tumour growth (Nature, DOI: 10.1038 / nature08062).
Importantly, the inhibitor was able to synergise with the doxorubicin and help to
delay tumour growth.
These data show that amino acid deficiency and consequent suppression of mTOR and HIF1α signalling underlie the
decreased tumour growth caused by Slc6a14 deletion.
D - Limonene — Suppresses * tumours, reduces * tumour size, prevention of mammary, liver, lung and other cancers [5], carcinogen removal, reduction * in
breast tumour growth [6], inhibition of mammary carcinomas [7], breast carcinoma regression in both early and late stage development [8].
This is problematic not only because the body isn't getting the nutritional and protective benefits, but also because un-metabolised Folic Acid has been shown to increase
cancer tumour growth.
The hydra tumour cells were shown to be invasive: if introduced into a healthy organism, they can
trigger tumour growth there.
Such a drug would block only the androgen receptor in prostate cells, and so stop the chain of reactions leading to
further tumour growth, says McCague.
«This might mean that strategies to control exosome release could be used to interrupt the ephrin - Eph signaling pathway and thereby
disrupt tumour growth,» he surmises.
For example, if your topic is a gene that controls cancer cells, a description of
sinister tumour growth in the relevant organ will probably do the trick.
Although it has been known that BET inhibitors are effective at
halting tumour growth, it has been unclear whether the drugs kill cancer cells outright or merely pause their growth.
La Vanguardia, EFE, La Sexta, RTVE, among other media, have published articles about the study by Jordi Casanova, at IRB Barcelona, that reveals that the same genes can
activate tumour growth and metastasis and that therefore some tumours are conferred metastatic capacity from their very outset.
Intriguingly, the pericyte Tie2
KO tumour growth and tumour vascular phenotype has striking parallels to the phenotype of tumours grown in Ang2 - deficient mice43.
We have identified a novel amino acid transporter, SLC6A14, as a drug target for cancer treatment; this transporter has functional features superior to those of SLC1A5, SLC7A5 and SLC7A11 to
support tumour growth.
The stem cell theory of cancer hypothesizes that «stem - like» cancer cells are responsible for the generation of tumours and for
sustaining tumour growth (reviewed in ref.17).
While tumour growth was delayed by apigenin, it didn't however stop the initial formation of breast cancer cells.
The study in question has been going on for the past eight years, and aimed to figure out the mechanism behind something called the Warburg effect — where cancer cells rapidly break down sugars — and how this, in turn,
stimulates tumour growth.
Conclusions «In conclusion, creatine supplementation was able to
mitigate tumour growth in rats -LSB-...], without affecting survival rate», the researchers summarize.
Promising results with these treatments is focusing attention on the molecular mechanisms
underlying tumour growth, which is changing the way research is conducted.
BET inhibitors
reduce tumour growth by blocking BET proteins, a family of proteins that control whether genes are switched on or off.
The mechanism of action of the experimental drugs nintedanib (Boehringer Ingelheim) and dovitinib (Novartis) precisely consists on blocking the formation of new blood vessels, so - called angiogenesis, which can lead to retardation in
tumour growth rates and limit its viability.
«With the degradation of the gel, the ROS level in the tumour site can be reduced, which also helps
inhibit tumour growth.»
Our research has identified a key process in
brain tumour growth that we were able to target with AZD8055,» says Luchman from the university's Cumming School of Medicine and a member of the HBI.