Sentences with phrase «tumour tissues from»

Analysis of transcriptomes in tumour tissues from wild - type mice and Slc6a14 - null mice indicated no compensatory changes in the expression of any other amino acid transporter mRNA.

In the mice, the neuron - like cells did not grow as quickly as the original cancer cells, and analyses of the tumour tissue from patients show that those with a high level of the estrogen receptor have a better survival rate that those with a low.

The researchers studied tumour tissue from patients, cultivated human tumour cells and tumours in mouse models for neuroblastoma.

(A) Demonstration of Slc6a14 mRNA up - regulation in PyMT - driven mammary tumours in mice; N, mammary tissue from wild - type mice; T, mammary tumour tissue from PyMT - Tg mice.

Not exact matches

They found 60 per cent fewer blood vessels surrounding tumour - like tissue grown from Down's stem cells than those from other volunteers.

The real test will be to inject these cells into mice and see if they form teratomas — tumours containing tissue or structures derived from all three germ layers.

The RTK profile of any tumour can be compared with that of healthy tissue from the same organ and treatment could be tailored accordingly.

«We therefore looked for patient characteristics that would account for this result; next generation sequencing (NGS) of the genes of interest was performed on the archival tissue samples from the patients» primary tumours,» explained Ciardiello.

For the first time ever, we could make a really comprehensive comparison of individual normal and tumour cells from the exact same type of tissue, taken at the same time, from the same person, and see how the cancer had developed.»

The team worked on tissue from three patients with colorectal cancer, taking normal bowel stem cells and cells from four different areas of the tumours.

When cancer cells from eg breast or lung tumours invade the bones through metastasis, the bone tissue is degraded.

These samples are then transferred to a mass spectrometer, which compares the combination of biomolecules with reference data collected from tumours and healthy tissue.

This has always been a worry with tissues produced from embryonic stem cells, as these have the capability to form tumours if any are left in their original state in the transplanted tissue.

By comparing the epigenetic profiles of gastric tumours to normal tissues from the same patient, we were able to identify those promoters specifically altered in GC tissues.»

He added that, aside from the hope of creating replacement tissues and organs for patients, the work could help scientists understand how to tackle unwanted blood vessel growth, such as that found in tumours.

In the new study, scientists at King's College London, led by Dr Anita Grigoriadis from the Breast Cancer Now Research Unit at King's College London, studied lymph node tissue and primary tumour samples from 309 breast cancer patients, who were treated between 1984 and 2002 at Guy's Hospital London.

«It's fascinating that it's so complicated», says Gerard, «there is a code we don't yet understand that differs from tissue to tissue — the number of chemokines and cytokines is distinct in each tissue type and the types of cells that enter and exit the tumour also differ».

Some receptors display a broad pattern of expression across tumour types, while others were expressed in cell lines from a particular tissue.

The smoke coming from the iKnife during resection of the tumour can analyse the lipid composition of tissue using a mass spectrophotometer http://publishing.rcseng.ac.uk/doi/full/10.1308/rcsbull.2016.88.

This is often how neurosurgeons actually identify tumour tissue for resection, as described from the study below and from use of the iKnife, which identifies malignant tissue and can be combined with a form of photodynamic therapy.