Sentences with phrase «tumour types»
The phrase "tumour types" refers to different kinds or categories of tumors, which are abnormal growths of cells in the body. Full definition
Researchers from Uppsala University, Sweden, and the Broad Institute, USA, have identified both similarities and differences between a single tumour type in multiple dogs breeds; a finding they believe parallels the situation in the cancer of human patients.
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By comparing the conversations, the researchers made the surprising discovery that similar reactions were taking place in different tumour types.
Seen in this light, a variety of tumour types can originate from the same organ.
The study is now focused on proposing a precise strategy for specific tumour types.
Researchers from SciLifeLab / Uppsala University, Sweden, and the Broad Institute, USA, have identified both similarities and differences between a single tumour type in multiple dogs breeds; a finding they believe parallels the situation in the cancer of human patients.
The use of whole genome sequencing enables researchers to accurately distinguish between tumour types with different treatment strategies.
«It could work in glioblastomas given that our study is based on brain progenitors, but we believe it could be extended to include other tumour types,» say the researchers.
An early sign that this might be the case came from a small clinical trial testing a new drug that has been developed without a particular tumour type in mind.
Research in each of the four tumour types holds different challenges, and communities are often smaller and less well developed than those studying more mainstream cancers.
The next step is to try and understand how these seemingly very different tumour types are able to adapt their energy production to grow.
Molecular characterization of the cells that undergo cell fate transition upon oncogenic Pik3ca expression demonstrated a profound oncogene - induced reprogramming of these newly formed cells and identified gene expression signatures, characteristic of the different cell fate switches, which was predictive of the cancer cell of origin, tumour type and clinical outcomes in women with breast cancers.
It is known that the genes that accumulate the most mutations are linked to the tumour type, and we found this too, however we showed that the mutational spectrum of a tumour is determined by breed type», says Dr. Ingegerd Elvers, a researcher with Professor Kerstin Lindblad - Toh at both Uppsala University and Broad Institute.
To help plug this diagnostic hole, Rebecca is leading the OCCAMS trial, a CRUK - funded multicentre study which is part of the International Cancer Genome Consortium (ICGC) global project to generate a comprehensive catalogue of genomic abnormalities in 50 tumour types.
Lung pathology experiences a paradigm shift moving from previously oversimplified two - part classification of nonsmall cell lung cancer and small cell lung cancer variants to a highly complex description of the biological variety of this tumour type.
It is known that the genes that accumulate the most mutations are linked to the tumour type, and we found this too, however we showed that the mutational spectrum of a tumour is determined by breed type», said Ingegerd Elvers who is a researcher in SciLifeLab Co-Director Kerstin Lindblad - Toh's group.