Sentences with word «tumourigenesis»
Our lab recently established a novel link whereby the cytokine interleukin (IL)-11, through its shared gp130 receptor, the associated Jak kinases and Stat3 signaling, promotes tumourigenesis.
onjcancercentre.org
Because interference with the gp130 / Stat3 signaling cascades limits the expansion of such intestinal (cancer) stem cells, the Stat3 - mediated non-oncogene addiction dependency can be therapeutically targeted in WNT - dependent tumourigenesis or in regenerative medicine.
Brca2 and Trp53 Deficiency Cooperate in the Progression of Mouse Prostate Tumourigenesis (2010), PLoS Genetics, DOI: 10.1371.