Sentences with phrase «tumours at»

Cancer in dogs is common: one in four dogs will develop dog tumours at some point in their life.

In contrast, no Slc6a14 − / − female with PyMT transgene developed tumours at 3 months of age; however, at 4 months of age, small tumour nodules became detectable (Figure 2B), indicating a marked delay in mammary tumour development in PyMT - Tg mice as a consequence of Slc6a14 deletion.

Tumour volume at 15 months of age, percentage of mice with palpable tumours at 10 months of age and age at which the first tumour was palpable in any of the mammary glands are shown (n = 10 per group; WT, Slc6a14 + / + background; KO, Slc6a14 − / − background).

And early results show it successfully reaches brain tumours at high enough levels for treatment.

PyMT - Tg female mice typically develop tumours at the age of ~ 10 weeks.

Breast cancer cells that spread to other parts of the body break off and leave the primary tumour at late stages of disease development, scientists from the Wellcome Trust Sanger Institute and their collaborators have found.

Michael decided to keep his tongue cancer secret after his doctor, who'd found a walnut - size tumour at the base of his tongue, revealed the surgery could have a serious impact his appearance.

Not exact matches

When placed at the site of a cancerous tumour in a rodent and «activated» by a scope with a light source, the compounds eradicated up to 100 % of cancer cells.

A doctor exams mammograms, a special type of X-ray of the breasts, which is used to detect tumours as part of a regular cancer prevention medical check - up at a clinic in Nice, south eastern France January 4, 2008.

Researchers have discovered that hydra (coral - like polyps that emerged hundreds of millions of years ago) form tumours similar to those found in humans.2 Thomas Bosch, at Kiel University, and Domazet - Lošo, from the Catholic University of Croatia in Zagreb unexpectedly discovered tumour - bearing polyps in two species of hydra.

For ladies, Cold food or drinks directly from the fridge without at least 2 hours thaw time, have the same uterus weakening effect, and will encourage the grow of tumours or cancer.

More displays like tonight at Swansea are badly needed to cure the first cancerous tumour, Wenger, and see him off.

In the round - up: Bottas «so hungry for the win» after two near - misses • Ricciardo not convinced to stay at Red Bull yet • Barrichello had surgery on tumour

Researchers at the University of Gothenburg are focusing on how HAMLET can be taken up into tumour cells.

Although these spots themselves are harmless, if some of the spots are bigger than a 50 cent coin, then it could be due to Neurofibromatosis (NF), which is a genetic disorder of the nervous system that causes abnormal cell growth of nerve tissues or benign tumours to form on the nerves anywhere in the body at any time.

Mali's President Ibrahim Boubacar Keita underwent an operation at a hospital in Paris this week as part of treatment for a benign tumour on his neck, the presidency said in a statement late on Wednesday.

«For example, the molecule known as cis - platin is very effective at treating cancerous tumours whereas trans - platin is ineffective.

«This phase III trial will be noteworthy for being the first prostate cancer trial to assess a biomarker, namely AR - V7 in circulating tumour cells, as a predictor of response at the same time as testing the efficacy of the drug,» Prof Taplin will conclude.

Liposomes, < 200 nm phospholipid vesicles, are longer retained in blood circulation and accumulate at pathological sites (tumours or inflamed tissues), leading to higher efficacy and lower systemic toxicity compared to the free drugs they encapsulate.

«Over 40 % of prostate cancers lose PTEN and some lose both PTEN and another tumour suppressor gene, INPP4B, but we didn't previously have a clear picture of how this affects tumour growth,» says IMED Biotech Unit scientist Sabina Cosulich, at AstraZeneca.

In conclusion, this new study identifies the cellular origin of Pik3ca - induced tumours and reveals that oncogenic Pik3ca activates a multipotent genetic program, setting the stage for future intratumoural heterogeneity at the earliest stage of tumor development.

To learn how prostate tumours become drug resistant, researchers led by Michael Karin at the University of California, San Diego, implanted prostate tumours into mice and gave them anti-androgens.

In addition, Natalia Martin - Orozco at the MD Anderson Cancer Center in Houston, Texas, and her colleagues noticed Th17 cells infiltrating cancerous tumours.

Such keys could be used to unlock a cancer drug - filled DNA box at a tumour site.

Ken Lavery, a maxillofacial consultant, who is carrying out similar research at Queen Victoria Hospital in East Grinstead, UK, says the technique offers huge potential for victims of gunshot or facial tumours.

The researchers then injected these tumour - specific cells into mice at the same time as injecting melanoma cells.

Dr Iain Foulkes, director of research and innovation at Cancer Research UK, said: «We urgently need new insights and treatments to tackle glioblastomas, one of the most common and difficult to treat forms of brain tumours.

«Naked mole rats have an additional barrier in the way of tumour progression,» says Seluanov, who presented the results at the Strategies for Engineered Negligible Senescence meeting in Cambridge, UK, last week.

Dr Harry Bulstrode at the University of Cambridge has received a Cancer Research UK Pioneer Award * to test the effect of the Zika virus on glioblastoma, the most common and aggressive form of brain tumour.

Until now, attempts at the «chemoprevention» of tumours have not been particularly successful.

Used on their own, chemotherapy drugs can cause a dip in the rate at which the tumour spreads.

In this study, the authors investigated the associations between various body measurements at baseline, mainly BMI and waist circumference, and the risk of prostate cancer incidence, with a focus on tumour stage and grade, and on mortality from prostate cancer.

The sub analysis presented at ESMO 2017 Congress included the 826 patients in MINDACT with a primary tumour size of less than 1 cm (pT1abpN0).

«We found that nearly one in four patients with small tumours are at risk of distant metastases and do benefit from chemotherapy,» said Dr Fatima Cardoso, senior author of the study, Co-Principal Investigator of MINDACT and Director of the Breast Unit of the Champalimaud Clinical Centre, Lisbon, Portugal.

Researchers at A * STAR's Singapore Immunology Network (SIgN) have discovered a new mechanism involving p53, the famous tumour suppressor, to fight against aggressive cancers.

«Our results suggest that we've been looking at these cancer drugs the wrong way — as tumour - targeting drugs — instead of what we now feel is their most important biological role: as immune stimulating therapy.»

Breast cancer patients who have radiotherapy targeted at the original tumour site experience fewer side effects five years after treatment than those who have whole breast radiotherapy, and their cancer is just as unlikely to return, according to trial results published in The Lancet.

The Lund University research team has looked at how cancer cells communicate with surrounding cells and how this encourages the development of malignant tumours.

The genetic changes in brain metastases are independent of any occurring at the same time in the primary tumour, and in metastases elsewhere in the body, the researchers said.

Scientists at The Institute of Cancer Research, London, analysed 177 tumour samples from patients with stage I non-seminomatous tumours enrolled in clinical trials through the Medical Research Council (MRC) Clinical Trials Unit.

Assessing just three features of a common kind of testicular cancer — called non-seminomatous germ cell tumour — can identify those at most at risk of relapse even where there is no evidence of tumour spread.

«Colon epithelial cells respond to the presence of these tumours and attempt to suppress them or at least control them through the BMP pathway.

A third group of mice received the standard high dose of chemotherapy at first, but once the animals» tumours started to shrink, the researchers dialled back the dose.

«The identification of markers that accurately predict, at an early stage, prostate tumours that are likely to metastasise could guide the urgency and aggressiveness of treatment — and this could save lives.»

A cancer biologist at the University of Turin in Italy, he had been studying targeted therapies — drugs tailored to the mutations that drive the growth of a tumour.

Steven Curley, associate professor of surgery at the University of Texas Anderson Cancer Center in Houston, has tested the gel on 15 people and is optimistic that it will provide a more effective treatment for liver cancer, including secondary tumours that have spread from other parts of the body.

Robert Coleman from the University of Sheffield, UK, says we had assumed that bisphosphonates simply wouldn't get into tumours other than bone cancers at any concentration that could make a difference.

Many people have experienced this among their family, friends or acquaintances: at first, the chemotherapy is extremely effective in cancer patients, although the tumour has metastasised, i.e. it has settled in remote tissue.

He has a tumour in his left lung, and the main challenge is to find out whether it is benign or malignant, precise and quick, at low cost for the patient.

And in 2010, a 46 - year - old woman developed multiple tumours in her kidney after having her own bone marrow stem cells injected at a private clinic in an attempt to treat her kidney failure.