Sentences with phrase «tumours developing»

Supposedly the chemical reduces the activity of PTEN cells, which are defective cells that are often the cause of tumours developing in the first place.

Cancer stem cells are strongly associated with the growth and recurrence of all cancers and are especially difficult to eradicate with normal treatment, which also leads to tumours developing resistance to other types of therapy.

«Benign'tumours develop through the same process, but do not spread to other parts of the body (metastatize) and, with very rare exceptions, are not life - threatening.

In addition, they showed for the first time that these genes are often the same as those that are altered in breast tumours - when a tumour develops, the DNA within the cancer cells themselves mutates.

Their model could ultimately help discover new drugs and cast new light on how tumours develop, grow and spread.

Mice given this bacterial strain and then exposed to enough UV light to cause skin tumours developed around 20 per cent fewer tumours than mice given a different strain (Science Advances, doi.org/gcz86k).

We believe that each dog breed may correspond to one type of B - or T - cell lymphoma and so studies within and between breeds gives us a unique possibility to understand how the genetic background affects what type of tumour develops, and how its progression is regulated», says Ingegerd Elvers.

Mice given this bacterial strain and then exposed to enough UV light to cause skin tumours developed around 20 per cent fewer tumours than mice given a different strain (Science Advances...

But for many of these patients the treatments don't work, or their tumours develop resistance after a relatively short time.

Tumours develop from normal human cells through a complex process with multiple stages.

In summary, we now beginning to obtain insight into the complexities of stromal interactions that support immune dysfunction as tumours develop, both via direct and indirect mechanisms by multiple players and at multiple sites.

Should a tumour develop, a visible mole will appear on the sk... Read more

Beginning in utero, the mice were exposed before tumours developed to either of the two different omega - 3s, allowing the researchers to make a comparison as to the effectiveness of the fatty acids at cancer tumour prevention.

Not exact matches

Also, why do cancer cells transplanted into healthy organs often not develop into tumours.

Chemotherapy (drug treatment) was later developed to destroy small tumour growths that were not treatable by other methods.

Radiation techniques were subsequently developed for use after surgery to control small tumour growths.

So reducing the risk of tumour formation or discovering a way to produce mature sperm in a test tube will have to be developed before we can even consider this in humans.»

Injections of killed stem cells, designed to help the immune system recognise cancers, have been found to protect mice from developing tumours

A woman in the US has developed a tumour - like growth near her spine eight years after a failed stem cell treatment to cure her paralysis

In fact, she had developed new tumours in her liver and chest.

Most females with a Y chromosome have underdeveloped gonads that are prone to developing tumours and usually removed.

This early stage research will explore how the virus targets stem cells and provide the starting point to develop new treatments that seek out the tumour and spare the surrounding healthy brain tissue.

Although Hochedlinger has so far studied his chimeras only until 13 weeks of age, none have yet developed tumours.

Around 10 per cent of people whose cancer has metastasised, or spread beyond the original site, develop brain tumours.

Resistant tumour cells tend to develop in oxygen - deprived parts of the tumour.

None developed into a malignant tumour.

Tumours grow through a process of Darwinian evolution, where cancer cells develop an advantageous mutation that allows them to survive and multiply, producing a population of cells which can mutate further.

It is estimated that between 30 % and 50 % of people over 50 will develop one of these tumours.

By contrast, rats and mice exposed to the same chemicals developed tumours in a matter of months (BMC Biology, doi.org/nhn).

By measuring levels of a modified protein, they could identify those who went on to develop secondary tumours within two years, with more than 90 per cent accuracy.

Even after three years, only one of the animals developed any tumours.

Cardiff University scientists have developed a novel anti-cancer stem cell agent capable of targeting aggressive tumour forming cells common to breast, pancreas, colon and prostate cancers.

But around 3 per cent of males developed a brain cancer known as malignant glioma, and up to 6 per cent grew heart tumours called schwannomas (BioRxiv, doi.org/bjfm).

Over this time, 30 per cent of the mice developed tumours around their body, including in their liver, colon, lungs and spleen.

Clarity can work on any organ, Chung says, and can even make developing embryos or tumours transparent.

«The coolest thing from an environmental perspective is that we can ask whether diet can influence this epigenetic process,» say Lanlan Shen of Baylor College of Medicine in Houston, Texas, whose group has developed a way to direct where methylation occurs, allowing them to show that epigenetic changes can trigger tumours (see main story).

«In most cases we think the body's growth control mechanisms eventually stop the cells from proliferating further, but in occasional cases where additional mutations occur in the clump of cells, a tumour will eventually develop,» says Andrew Wilkie also of the University of Oxford, who supervised the work.

Several drugs have been approved to target EGFRmutations, but tumours invariably develop resistance to them.

This finding is significant in helping to develop personalised diagnostic tests for patients with colorectal cancer based on the genetic changes present in each individual's colon tumour.

A woman in the US has developed a tumour - like growth eight years after a stem cell treatment to cure her paralysis failed.

And in 2010, a 46 - year - old woman developed multiple tumours in her kidney after having her own bone marrow stem cells injected at a private clinic in an attempt to treat her kidney failure.

A more highly publicised case was in 2009, when an Israeli teenager developed brain and spinal tumours after receiving several implants of fetal stem cells in Moscow to treat a rare degenerative condition.

Germ cells can develop into tumours — both benign and malignant — particularly in the testes or ovaries, where the cells are normally found.

A new imaging technology to grade tumour biopsies has been developed by a team of scientists led by the Department of Physics and the Department of Surgery and Cancer at Imperial College London.

The researchers, at The Institute of Cancer Research, London, and The Royal Marsden NHS Foundation Trust, say their test is the first developed for a precision prostate cancer therapy targeted at specific genetic faults within tumours.

Mice that received higher doses of the drug developed smaller tumours.

In Nature Communications, the scientists conclude that the JAK / STAT signalling pathway, known to be tightly linked to inflammatory processes and tumour growth, determines where, when and how a wing develops in Drosophila.

A non-invasive, low cost blood test that could help doctors diagnose some types of malignant childhood tumour has been developed by researchers at the University of Cambridge and Addenbrooke's Hospital, Cambridge University Health NHS Foundation Trust.

In research funded by Sparks charity, Great Ormond Street Hospital Children's Charity and Cancer Research UK, researchers at the University of Cambridge have developed a test for blood and cerebrospinal fluid samples that looks for a specific panel of four pieces of short genetic code known as microRNAs, which are found in greater quantities in malignant germ cell tumours.

Whilst further study is needed, we are building evidence to show that genetic diversity in a bacterial infection or in a tumour being treated could lay the foundation for resistance to the therapy and affect how quickly resistance develops.»