Sentences with phrase «tumours grow»

Providence, RI (OBBeC)- According to a report from Brown University, researchers from the university and other institutions have developed a computational computer model of how brain tumours grow and evolve.

But some tumours grow so rapidly their interiors become starved of blood and oxygen, and turn into «necrotic» regions full of dead and dying cells.

The animals have a turtle - specific herpesvirus that causes fibropapillomatosis — a condition in which disfiguring tumours grow on the eyes, flippers, tail, shell or internal organs.

«Some tissues showed faster methylation than others, for example in the liver, colon and spleen, and that's exactly where we saw the tumours grow,» says Shen.

Tumours grow through a process of Darwinian evolution, where cancer cells develop an advantageous mutation that allows them to survive and multiply, producing a population of cells which can mutate further.

Because tumours grow and divide rapidly, they quickly exhaust local supplies of oxygen.

The team found that exposing samples of human glioblastoma tumours grown in a dish to the Zika virus destroyed the cancer stem cells.

Lower doses of resveratrol were twice as effective as the higher dose in stopping tumours growing, although this effect was only seen in animals fed a high - fat diet.

In the second study, Thomas Gajewski at the University of Chicago and colleagues noticed differences in how quickly tumours grew in two groups of mice with different sets of gut microbes.

(b) Quantification of microvessel density (MVD) in CD31 - stained tumours grown in WT and Tie2PEKO mice.

Intriguingly, the pericyte Tie2 KO tumour growth and tumour vascular phenotype has striking parallels to the phenotype of tumours grown in Ang2 - deficient mice43.

(d) Representative images of the tumour vasculature stained for CD31 and NG2 in tumours grown in WT and Tie2PEKO mice.

Significantly more microspheres accumulated in tumours grown in Tie2PEKO mice 24 h after sphere injection (Fig. 6f — h).

(d) Quantification of tumour weight of LLC tumours grown subcutaneously for 12 days in WT and Tie2PEKO mice.

Co-localization analysis of pericytes (NG2) and EC (CD31) identified a moderate, albeit non-significant reduction of pericyte coverage in tumours grown in Tie2PEKO mice (Fig. 6d, e).

(g) Quantification of microspheres per mm2 in tumours grown in WT and Tie2PEKO mice normalized to WT average.

(c) Representative images of LLC tumours grown subcutaneously for 12 days in WT and Tie2PEKO mice.

(a) Representative images of B16 tumours grown subcutaneously for 14 days in WT and Tie2PEKO mice.

(e) Quantitative analysis of pericyte coverage in tumours grown in Tie2PEKO mice normalized to WT average.

Dr Guerra first showed ten years ago that this mechanism also works against cancerous tumours — demonstrated by the fact that tumours grew faster in mice that had their NKG2D activity supressed.

This disease, which affects 1 in 50,000 British citizens, occurs when a tumour grows on the adrenal glands and forces them to produce too much cortisol.

Not exact matches

For ladies, Cold food or drinks directly from the fridge without at least 2 hours thaw time, have the same uterus weakening effect, and will encourage the grow of tumours or cancer.

Anti-androgen drugs can cause these tumours to regress, but eventually they become resistant to them and start to grow again.

Tumours in these mice grew 50 per cent more slowly than those in healthy mice, indicating that one extra copy of the gene has a significant effect on tumour growth (Nature, DOI: 10.1038 / nature08062).

This time, she was given different chemotherapy — docetaxel and gemcitabine — as it was assumed that her cancer had grown resistant to the previous drugs, and, after several weeks, the tumours had shrunk right down.

They found 60 per cent fewer blood vessels surrounding tumour - like tissue grown from Down's stem cells than those from other volunteers.

The magnets can sculpt balls into shapes that resemble tumours and tissues growing in the body.

But as inflammation is known to promote the growth of cancer, they assumed that the cells were helping the tumours to grow.

These were released into tumour cells that had been taken from glioblastoma patients and grown in the lab.

Like a cruel form of mind control, some cancerous tumours can reprogram some immune cells to «block» other immune cells from attacking, leaving the tumour free to grow.

The tumour cells pass between individuals during biting behaviour and tumours form predominantly around the face and neck, grow rapidly and cause close to 100 per cent mortality.

But around 3 per cent of males developed a brain cancer known as malignant glioma, and up to 6 per cent grew heart tumours called schwannomas (BioRxiv, doi.org/bjfm).

This means that the cancer cells are no longer able to communicate as effectively and the tumour does not grow as it otherwise would.

One approach would be to identify immune cells in a tumour, grow them in a lab, and then infuse them back into the patient — a technique called adoptive cell transfer.

He likens them to moles in the skin, which are also benign tumours that stop growing.

Some cancer drugs stop tumours by blocking the signalling pathway that allows the tumour to grow, effectively placing a lock on a protein «door».

There is a growing number of lawsuits against such clinics and a few cases have been reported of tumours or excessive tissue growth (see «Ongoing stem cell trials» below).

They include growing evidence that nicotine promotes tumour growth.

Most of the keys will be useless, but one is bound to fit the lock eventually, and the tumour can start growing again.

The data gathered from their experiments suggest a feed - forward loop, in which tumours not only use lipids as «building blocks» to grow, but they can regulate their host's lipid metabolism to increase production of these lipids.

His immune system has begun to attack the tumours; some have stopped growing, others have shrunk.

Acidic conditions are found in inflamed tissue and in growing tumours that are beginning to spread to other sites in the body.

Around 70 % of all cases of breast cancer are oestrogen - receptor positive, meaning that the cancer cells have a particular protein (known as a receptor) that responds to the female sex hormone oestrogen, enabling the tumour to grow.

Growing mini tumours in the lab from a patient's own cells could help doctors discover the best way to treat each person, homing in on the right drugs to use

The altered gene expression may have led to slower - growing kidney tumours.

After treatment, such dormant cells will start to divide and tumours will grow.

As well as weakening the tumour, which makes it less able to grow and spread to other parts of the body, the drug made blood vessels become more leaky, enabling more chemotherapy drugs to spill into the tumour.

But there's a catch: viruses and tumour cells can also exploit the UPR for their own ends, enabling them to grow at a faster rate and to thwart the body's immune response.

Their model could ultimately help discover new drugs and cast new light on how tumours develop, grow and spread.

Growing them in animals makes for more lifelike tumours, and can produce large quantities of tissue for study.