Sentences with phrase «turn inhibits»

Namely, even in small absorbed quantities they react to activate Nrf2 (a master regulator of antioxidant response), which in turn inhibits NF - κB (a master regulator of inflammatory / innate immune responses).

When ammonia accumulates in the muscles it causes muscular fatigue that in turn inhibits muscle protein contractility that generally will accumulate in the brain and serum while exercising.

Taking too much sugar leads to high insulin levels, which in turn inhibits the production of testosterone.

The explanation, they demonstrated, is that the loss of p14 ARF leads to the deregulation of another protein, Mdm2, which in turn inhibits p53.

It does so by activating the transcription factor STAT3, which in turn inhibits expression of the miR - 34a gene by directly binding to it.»

This in turn inhibits the release of glutamate from the cells projecting from the cortex.

But this machinery creates problems of soil impaction, destroying soil structure and creating impermeable surfaces, in turn inhibiting filtration and root development.

At extreme levels of threat, the PAG may in turn inhibit more complex control processes when a fast and indeed obligatory response is required, preparing the organism for survival and possible tissue damage (3, 16 — 18, 21).

Binding dopamine receptors, which works to reduce secretion of prolactin by the pituitary gland, in turn inhibiting estrogen and progesterone.

The entire function of lactic acid fermentation is based on the capability of lactic acid bacteria to produce acids, which in turn inhibit the growth of non-desirable organisms.

Not exact matches

Not everything is going to go exactly as planned and people, permitting, laws and codes can quickly turn to roadblocks inhibiting your business from growing.

And that, in turn, could inhibit the central bank from providing sufficient policy easing to support the economy.

Fourth, profits are starting to turn down and regulatory pressure is inhibiting lending to small and medium sized businesses.

Our present concept of Homo Faber («Man, the Worker») has, as we have seen, inhibited this exercise of freedom, causing men and women to turn potentially playful experiences into attempts to escape tension, boredom, or fatigue, or into exercises geared at accomplishing something constructive.

In the experience of the early church the Temple turned out to have inhibited the missionary purpose of the people of God rather than facilitate it.

Turns out, they're a great source of vitamin C and fiber, as well as antioxidants, and some preliminary research suggests that raspberry ketones (don't ask me what exactly a ketone is...) could play a role in inhibiting the growth of certain cancers.

Carbon monoxide and nicotine are released into the uterus which inhibits oxygen getting to the cells, in turn creating birth defects.

You may also feel disappointed by this unexpected turn of events, which may inhibit the let - down and flow of your breast milk.

Turns out, our timing was off, and life took us in a different direction with a loss of a job, a move out of town, and grad school; all of which inhibited adoption for that season.

Some tools used were pudding caps, a padded hat that would protect the head when the child fell so that their mind was not turned to, essentially, pudding, and babies and toddlers, regardless of sex, were kept in long petticoats and gowns that inhibited crawling and made it easy to toilet train.

Increased ceramide activity, in turn, inhibits cells that would normally produce VEGF and encourage blood vessel growth.

Silt - bearing runoff from many activities including construction sites, forestry and farms can inhibit the penetration of sunlight through the water column restricting photosynthesis and causing blanketing of the lake or river bed which in turns damages the ecology.

These new insights into how the kinase is turned on provides a starting point for designing molecules to inhibit it, Muir said.

«We were able to abolish sociability by inhibiting these neurons and we could magnify and prolong sociability by turning them on,» said Anderson.

Inhibiting BACE1 will limit the production of Aβ which, in turn, should reduce the production of neurotoxic fibrils and plaques.

Substances produced by a harmful bacterium in the lungs of cystic fibrosis patients may enhance the growth of other bacteria that, in turn, inhibit the harmful bacterium's biofilm, according to new research published in PLOS Pathogens.

Substances produced by a harmful bacterium in the lungs of cystic fibrosis patients may enhance the growth of other bacteria that, in turn, inhibit the harmful bacterium's biofilm, according to new research.

When exposed to oxygen, malathion turns into malaoxon, which kills insects by inhibiting an enzyme, acetylcholinesterase, that breaks down acetylcholine.

One of the most potent compounds, WWL113, turned out to work principally by inhibiting Ces3, a serine hydrolase enzyme that scientists have not studied in the context of obesity or diabetes.

The study also presents a new model that explains how growth promoting genes could be epigenetically turned on and growth inhibiting genes could be epigenetically turned off in cancer cell formation.

And it turns out that bosutinib may inhibit the activity of exactly the kinases that EGFR - dependent lung cancers need to mutate around the challenge of EGFR inhibitors.

Recently, many scientists came to suspect that a protein called NF - κB, a master regulator of infection and inflammation, was at work; in 1996, several groups had found that it also inhibited cell death, which can lead to tumor formation.To find out whether suspicions about NF - κB were well - founded, molecular biologist Michael Karin of the University of California, San Diego, and his colleagues turned to a mouse model of colitis.

Although we have long known that this signal strongly inhibits protein synthesis in general, during hemoglobin gene expression it first plays its indispensable, positive role before being turned off promptly to allow for massive hemoglobin formation needed for breathing,» said Prof. Raymond Kaempfer, the Dr. Philip M. Marcus Professor of Molecular Biology and Cancer Research at the Hebrew University of Jerusalem.

Blocking Wingless / beta - catenin also inhibits the MGMT enzyme, which in turn prevents cytostatic resistance.

The fMRI profile and mechanistic defects of the mice with inhibited RbAp48 returned to normal when the inhibition was turned off.

RNA interference, something Kissler learned as a post-doc at MIT, is a process that uses strands of genetic material called RNA to inhibit the expressions of genes — meaning researchers can manually decide which genes get turned on or off and when by using RNA to block the pathways that lead to the genes» switches.

In the development of epilepsy, inhibiting COX - 2 turns out to be complicated as well. Ray Dingledine, chair of pharmacology at Emory, and colleagues have a new paper showing that COX - 2 has both protective and harmful effects in mice after status epilepticus, depending on the timing and what cells the enzyme comes from.

His team used this light to inhibit, or turn off, certain neurons that release dopamine in mice.

When there is insulin resistance, insulin pathway is inhibited, this, in turn, turns on a number of other pathways that exasperate the lipogenic signal.

Akt can phosphorylate and inhibit the activation of Foxo1 and Foxo3a, in turn suppressing the transcription of Foxp3 (16).

Also, this vitamin inhibits a process called aromatization which makes testosterone turn into estrogen in men.

Another terpene, α - pinene is released by plants as a volatile defense mechanism, yet seems to decrease inflammation by inhibiting NF - κB (Nuclear Factor Kappa B).11 NF - κB regulates our immune response and is turned on in response to harmful states like infection.

It turns out that when applied to skin cells, avenanthramides are able to inhibit the exact same pro-inflammatory proteins that oatmeal can: IL - 8, TNF - A, NF - kappaB, and arachidonic acid.

Inhibits inflammation that in turn weakens and even kills cancerous cells in people with cancer.

It inhibits the activity of 5 Alpha Reductase and prevents it from turning Testosterone into DHT.

Experiments have shown that unsaturated fatty acids inhibit the growth of the human fetus15 and, in the absence of omega - 3 and omega - 6, both short - term and long - term memory of the fetus are improved.16 In a 2016 study, Taiwanese scientists reported that «essential» unsaturated fats from fish oil (omega - 3) are toxic to the aging brain, 17 and as it turns out: fish oil isn't even good for fish!

Researchers have also found that increasing the number of beneficial bacteria causes cholesterol levels to decrease, due to the ability of bacteria to turn dietary fiber into the short - chain fatty acids that inhibit cholesterol.

Basically, it inhibits estrogen which in turn stops that estrogen from stimulating breast cancer cell growth.

According to studies at the Forest Research Institute in Malaysia, Assam fruit has nourishing antioxidants, lowers blood lipid levels, and also inhibits lipogenesis, a metabolic process that turns carbohydrates into fat.

Cortisol also inhibits sodium loss through the small intestine, which in turn raises blood pressure.