Blood Cells Turned into Beating Heart Cells In a collaboration between the Kimmel Cancer Center, Institute for Cell Engineering, and Department of Biomedical Engineering, researchers successfully
turned blood stem cells into functional, beating heart cells.
Not exact matches
These unformed
stem cells have the ability to
turn into mature
blood cells — and could save the life of someone who needs a bone marrow transplant, and possibly other diseases, since
stem - cell research remains in its infancy, really.
It has been assumed that activation of HOX genes
turns normal
blood cells into leukemia cells by initiating
stem cell - like self - renewal.
«In effort to treat rare blinding disease, researchers
turn stem cells into
blood vessels: Patients around the world contribute skin samples to test potential new therapy.»
This elusive stability must be achieved before
stem cell supplies can be kept on hand until it is time to
turn them into replacements for say misshapen red
blood cells seen in sickle cell anemia or abnormal white
blood cells causing leukemia.
Other adult
stems cells exist — such as hematopoietic
stem cells, which can generate all types of
blood cell and mesenchymal
stem cells, which can
turn into bone, fat and cartilage cells.
Lee conducted a real - time attempt to reproduce a controversial experiment published in Nature in which researchers claimed to have
turned adult mouse
blood cells into pluripotent
stem cells.
In this study, researchers took cells from patients with
blood cancer MDS and
turned them into
stem cells to study the deletions of human chromosome 7 often associated with this disease.
By
turning on a several genes in adult cells, scientists can transform skin or
blood cells into
stem cells that can become every cell type in the body — without the ethical and practical complications of using embryos or oocytes.
What he instead plans to do is
turn the iPSCs into
blood - forming
stem cells, which when transplanted into the body would give rise to all of the cell types found in the
blood.
Ultimately, this activity increases cellular regeneration, or self - renewal,
turning white
blood cell precursors into leukemia
stem cells.
UVA scientists were surprised to discover that the heart's inner lining forms from the same
stem cells, known as «precursor cells,» that
turn into
blood.
In previous experiments, neural
stem cells have been able to integrate into developing embryos and
turn into many different types of cells, including heart and liver (ScienceNOW, 1 June) and even
blood (21 January 1999).
In
turn, the niche cells control the production and also the differentiation of the
blood stem cells.
The work, as detailed in the journal
Stem Cells, shows that only a bit of creative manipulation is needed to
turn skin cells into human white
blood cells.
The researchers, however, observed that older brains formed fewer
blood vessels and possessed a smaller pool of progenitor cells — the early descendants of
stem cells that
turn into neurons.
Stem cells allow researchers to collect
blood or skin samples from living patients and
turn them into the brain cells affected by the disease — neural progenitor cells (NPCs) and neurons.
Meanwhile, Dr. Mick Bhatia's group at the
Stem Cell and Cancer Research Institute at McMaster University found a way to make human skin cells sing «Any Way You Want Me,»
turning directly into
blood cells without a pluripotent cell step in between.