Lanza's dream of
turning human embryonic stem cells into therapies for the sick and the suffering is taking a huge step closer to reality.
The company has
turned human embryonic stem cells into retinal pigment epithelial cells, which will be surgically implanted into the eye.
Forbes, Robert Langreth, February 20, 2008: In progress toward a stem - cell treatment for diabetes, researchers at a small San Diego biotech company have devised a procedure for
turning human embryonic stems cells into insulin - producing cells inside mice.
Not exact matches
Although primed, post-implantation
embryonic stem cells can still
turn into any type of
human cell, they are more difficult to work with than the pre-implantation, naive
cells.
Scientists recently announced that they have found a way to
turn human skin into
cells that have all the therapeutic potential of
embryonic stem cells.
While conservatives in Congress took
turns echoing George W. Bush's opposition to destroying
human embryos for research, Lensch's colleague Paul Lerou stepped into a small room behind a heavy black curtain to check up on a line of nonpresidential
embryonic stem cells.
- Our results provide new insights into the mechanisms of how POLR3G gene regulates
stem cell state, which in
turn sheds light on the complex mechanisms with which
human embryonic stem cells both self - renew and maintain the ability to differentiate.
It is possible to force
human skin
cells to
turn back into
embryonic stem cells in the lab, but this doesn't seem to be something we are able to achieve without intervention.
Both teams successfully used these to reprogramme skin
cells in a lab dish into
cells resembling
embryonic stem cells, which have the ability to
turn into any tissue of the
human body.
Experiments conducted by lead author Fatima Syed - Picard, Ph.D., also of Pitt's Department of Ophthalmology, and the team showed that
stem cells of the dental pulp, obtained from routine
human third molar, or wisdom tooth, extractions performed at Pitt's School of Dental Medicine, could be
turned into corneal stromal
cells called keratocytes, which have the same
embryonic origin.
Human embryonic stem cells can
turn into a variety of different
cell types, including (A) gut, (B) neural
cells, (C) bone marrow
cells, (D) cartilage, (E) muscle, and (F) kidney
cells.
To overcome these hurdles, Bhatia and her team reprogrammed
human skin
cells into induced pluripotent
stem cells (iPSCs)--
embryonic - like
stem cells capable of
turning into other specific
cell types relevant for studying a particular disease.