Sentences with phrase «turning skin cells»
In lab experiments, researchers found that just one touch of the TNT completely repaired the injured legs of lab mice over a three - week period by turning the skin cells of the animals into vascular cells.
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Clive Svendsen from Cedars Sinai introduces the work of the HD iPSC Consortium - a group of scientists working on turning skin cells into brain cells.
While no one factor was sufficient by itself to change the cells, the combination of all the factors did the trick, turning the skin cells into stem cells.
Other researchers have bypassed the pluripotent stem cell stage while turning skin cells into neurons and other specialized cells, Zhang acknowledges, but the new research, just published in Cell Reports, had a different goal.
Two teams of researchers have found different ways to perform the same biological identity swap: turning skin cells into neurons.
Turning skin cells into sperm may one day help some infertile men have babies.
A virus containing the gene that codes for two molecular «switches» essential for turning skin cells into brown fat was used to trigger the change (Nature, DOI: 10.1038 / nature08262).
Researchers in California have turned skin cells in mice into insulin producing beta cells, effectively curing the animals of diabetes.
A major breakthrough occurred last year when scientists figured out how to turn skin cells into ES - like cells that could serve the same purpose (Science, 23 November 2007, p. 1224).
The remarkable discovery that it is possible to turn skin cells back to an embryonic state, when they have the potential to become any type of cell in the body, could open up a huge range of possibilities.
Vania Broccoli of the San Raffaele Scientific Institute in Milan, Italy, and colleagues have worked out how to turn skin cells into specialised neurons that make dopamine.
Other researchers had successfully used a similar process to turn skin cells into embryonic - like cells called induced pluripotent stem cells, and then grow those iPS cells into nerve cells, but Wernig's lab was the first to convert skin cells directly into nerve cells without the intermediate iPS cell step.
«Our idea was to turn skin cells to neural progenitors, cells that can produce cells relating to the neural tissue.
What may sound like an ad for a futuristic tanning salon is actually a triumph of gene therapy research: A tweaked gene turns the skin cells of albino mice a dark color that lasts for weeks.
Another past study from Yoo's team showed that exposure to the same two microRNAs, miR - 9 and miR - 124, plus a different mix of transcription factors could turn skin cells into a different type of neuron.
After much experimentation with multiple combinations, the researchers found that adding two more signals to the mix — transcription factors called ISL1 and LHX3 — turned the skin cells into spinal cord motor neurons in about 30 days.
In a scientific first, researchers at the Gladstone Institutes turned skin cells from mice into stem cells by activating a specific gene in the cells using CRISPR technology.
Gladstone scientist Dr. Sheng Ding has exposed more chameleon - like qualities of the human skin cell, using chemical cocktails to turn skin cells into fully functional brain, heart, liver, and insulin - producing pancreas cells.
Stem cell scientist Sheng Ding has used his unique drug cocktails to turn skin cells into brain, heart, liver, and insulin - producing pancreas cells.
The work, as detailed in the journal Stem Cells, shows that only a bit of creative manipulation is needed to turn skin cells into human white blood cells.
In response, the cells underwent changes indicative of senescence, ceasing cell division and churning out key SASP factors.7 Notably, astrocytes were much more vulnerable to paraquat than skin cells: astrocytes went senescent at a lower concentration of the toxin than was required for skin cells, and the doses that turned skin cells senescent killed astrocytes outright.7
The latest study, published in Cell Stem Cell, offers a third way to turn skin cells into stem cells by directly manipulating the cells» genome using CRISPR gene regulation techniques.
NYSCF Research Institute scientists in collaboration with researchers at the Icahn School of Medicine at Mount Sinai refined a technique to turn skin cells from patients...
Not exact matches
I'm glad we didn't, becuase as it turns out, the DermaFrida wasn't making her dry skin worse, it was just making it briefly appear more prominent as it lifted the dried skin cells and then gently scrubbed them away.
The epigenetic programming established during development is normally quite stable (skin cells do not spontaneously turn into brain cells during adult life), but it is not irreversible.
Treating the skin cells with a biochemical cocktail to promote neural stem cell characteristics seemed to do the trick, turning it into a one - step process, he and his colleague report today in Science Translational Medicine.
To solve these problems, Hingtgen's group wanted to see whether they could skip a step in the genetic reprogramming process, which first transforms adult skin cells into standard stem cells and then turns those into neural stem cells.
The idea fell out of favour following the scandal of 2005, and after the development of a way to turn ordinary skin cells into so - called induced pluripotent stem cells (iPS cells), which behave rather like hESCs.
Skin cells from a woman with diabetes have been turned into insulin - producing cells, via a cloning technique similar to the one that made Dolly the sheep
Using viral gene insertion and regulatory proteins, researchers turned adult human skin cells directly into adult human blood cells, without first returning them to a fully pluripotent state.
«In effort to treat rare blinding disease, researchers turn stem cells into blood vessels: Patients around the world contribute skin samples to test potential new therapy.»
Cellular reprogramming turns an adult cell, such as a skin cell, into an induced pluripotent stem (iPS) cell.
Anand and his colleague Susan McKay started with human skin cells, which they turned into induced pluripotent stem cells (iPSCs) using a tried - and - tested method.
Overexpression of ZNF217 provides an advantage to tumor cells by allowing cells to infinitely proliferate and turning down pathways that typically tell cells to mature into functional cells (bone, blood, skin cells).
The neural progenitor cells used were derived from iPSCs (induced pluripotent stem cells), which were in turn derived from donor skin cells.
The most common type of skin lymphoma is caused by the fact that specific immune cells — CD4 - T - lymphocyttes — turn into cancer cells.
Scientists may have turned mouse skin cells into embryolike stem cells, but prior claims for the power of adult cells have yet to stand the test of time
Such a recollection can be an advantage if scientists are looking to turn a reprogrammed skin cell back into skin cells, he noted.
Wells's team first turned human skin cells into pluripotent stem cells, which can grow into any type of tissue.
Other genes can prompt skin cells to turn directly into neurons or blood cells.
They then tried to reprogram skin cells from the animals, turning them into induced pluripotent stem cells (iPS), which are capable of forming other types of cell.
New experiments by UC Berkeley and UCSF researchers suggest that immortalization of skin cells, which is essential to turning them cancerous, is a two - step process: a mutation in nevus cells slightly raises levels of telomerase, which keep the cells alive long enough for a second change, still unknown, that up - regulates telomerase to make the cells immortal and malignant.
By turning on a several genes in adult cells, scientists can transform skin or blood cells into stem cells that can become every cell type in the body — without the ethical and practical complications of using embryos or oocytes.
Like Medieval alchemists who searched for an elixir that could turn base metals into gold, biology's modern alchemists have learned how to use oocytes to turn normal skin cells into valuable stem cells, and even whole animals.
In the present study, her team took skin cells from patients with lissencephaly and turned them into iPS cells, which they then cultivated under special conditions into neuronal stem cells and neurons that are copies of those in the patients» brains.
Scientists recently announced that they have found a way to turn human skin into cells that have all the therapeutic potential of embryonic stem cells.
In the last few years, researchers have learned how to turn embryonic stem cells into all sorts of different cell types, such as skin cells, heart
For one thing, if a skin cell can be turned into a far more versatile embryonic cell, then maybe there's a way to turn any specialised cell directly into another.
It turns out that keratinocytes, or skin cells, migrate through the outer skin to maintain hair follicles.
«Use of induced pluripotent stem cell (iPSC) technology» — which involves taking skin cells from patients and reprogramming them into embryonic - like stem cells capable of turning into other specific cell types relevant for studying a particular disease — «makes it possible to model dementias that affect people later in life,» says senior study author Catherine Verfaillie of KU Leuven.