Decreased adherence and increased stiffness of cells overexpressing centrosomal ninein ‐ like protein causes dissemination of wild ‐
type cells undergoing mitosis from mosaic epithelia.
Not exact matches
In the clearest possible case, the ANT - OAR
cell would differ from a zygote on all of the parameters noted above: The ANT - OAR
cell would have a pattern of gene expression that is clearly distinct from a zygote; it would generate a homogeneous population of
cells rather than multiple
cell types; it would
undergo simple cleavage divisions and not produce any multicellular structures.
Molecular characterization of the
cells that
undergo cell fate transition upon oncogenic Pik3ca expression demonstrated a profound oncogene - induced reprogramming of these newly formed
cells and identified gene expression signatures, characteristic of the different
cell fate switches, which was predictive of the cancer
cell of origin, tumour
type and clinical outcomes in women with breast cancers.
This study showed that mtDNA levels are higher in the surviving cholinergic neurons of the brainstem, but with both
cell -
types that
undergo profound degeneration during Parkinson's disease.
One likely reason for this is that animals
undergo cellular differentiation; human life begins as a single
cell that differentiates into the various
cell types needed for different organs, body parts, blood, the immune system, etc..
During the first hours after fertilization, the two separate genomes
undergo reprogramming events that presumably function to erase the memory of the differentiated
cell type and establish a state of totipotency.
For instance, Hohl and his colleagues noticed that fungal
cells being engulfed by neutrophils, a
type of white blood
cell, appeared to be
undergoing programmed
cell death.
Some sentries of the immune system — so - called B
cells, which are charged with checking out the passersby of the bloodstream —
undergo a
type of basic training.
C. albicans is known to
undergo a parasexual cycle involving heterothallic fusion of α and a mating
type cells followed by stochastic, concerted loss of chromosomes [44].
But when a
cell prepares to
undergo mitosis — a
type of
cell division — those strings of DNA must condense into easy - to - transfer cylinders.
Briefly, single -
cell suspensions of C57BL / 6 KO and wild -
type lymphocytes, which had
undergone a 96 hr in vitro boost with γ - irradiated (3,000 rad) BALB / c stimulator lymphocytes, were added to 96 - well microtiter plates (Corning Inc., Corning, NY) along with 2 × 104 51Cr - labeled BALB / c corneal epithelial or endothelial
cells in a total volume of 200 μl / well.
MZdicer mutants
undergo axis formation and differentiate multiple
cell types but display abnormal morphogenesis during gastrulation, brain formation, somitogenesis, and heart development.
This spectrum in gene expression is reflected in the ability of
cells to
undergo self - renewal or to form specific differentiated
cell types.