Sentences with phrase «type control mice»

As shown in Table 1, all four lines exhibited significant increases in muscle weights compared to wild type control mice.

As the mice aged, their motor performance on a rotarod test (which measures how long the mouse can remain on a rotating rod) became impaired and the length of their strides were significantly shorter than the wild type control mice.

Not exact matches

The study also found that SNCA mice displayed fragmented nighttime activity patterns compared to wild type controls and appeared to have a reduced overall sleep time.

Several years ago, while creating a genetically engineered mouse that expresses high levels of the mouse HMGA1 gene to investigate its role in leukemia, Resar and her colleagues made the chance finding that the intestines of these animals were much larger and heavier than those of «wild - type» animals (or control mice that were not genetically modified).

To explore these questions Akiko Iwasaki, professor of immunobiology and investigator of the Howard Hughes Medical Institute, and her co-authors observed replication of the Zika virus in the vaginal tissue of control, wild - type mice (genetically unmodified mice) and mice lacking genes that regulate immune system proteins known as type I interferons.

«This finding suggests that there are two different types of neurons, ESP1 and predator neurons, and only the former controls sexual behaviors in female mice,» explains Touhara.

In experiments in mice, UC San Francisco researchers have discovered that regulatory T cells (Tregs; pronounced «tee - regs»), a type of immune cell generally associated with controlling inflammation, directly trigger stem cells in the skin to promote healthy hair growth.

For prevention studies, they injected mouse α - syn synthetic preformed fibrils into wild - type, normal mice, as a control, and then immediately treated the mice with Syn303, one of the MAbs used (or IgG, another type of common antibody, for the control mice).

The researchers treated mice with two types of thymus tumor with each peptibody, a control peptibody and an antibody against Gr - 1.

In the Nature papers, the researchers compared gene transcription, chromatin modification and other processes that control gene activity in a wide range of mouse and human tissues and cell types.

(A) Histology of control diet (CD) and Western diet (WD)- fed wild - type (WT) and FXR knockout (KO) mice of both genders.

Cortical bone — one of the two types of bone tissue — was stronger in the treated mice than the controls, the researchers report online today in the Proceedings of the National Academy of Sciences.

Specifically, rod - mediated inner retinal responses to dim light flashes were faster in diseased mice than in their wild - type controls.

Separately, both types of mice got «sham» procedures without the electrical pulse as controls.

While mice that received ISO - 1 remained healthy, the control group developed high blood sugar — a key marker for Type 1 diabetes.

All clones with the wild type Tyr302, including the Envs from the viral innoculum and two Envs from X4 - ZFN mice utilized CXCR4 approximately 1000-fold more efficiently than CCR5 and comparably to the X4 - tropic control TYBE (Figure 6C).

C57BL / 6 wild - type mice (The Jackson Laboratory, 000664; n = 8) were used as an additional control for comparison purposes, but were not included in any statistical analyses.

The lab mice in the study that had Type I diabetes demonstrated an impressive level of control over their blood sugar for more than two days following the injection of the newly developed insulin / glucosamine compound.

Male or female (5 - 6 wks old) wild type and genetically modified mice (as required for individual investigator's protocols) will be fed a high fat high sucrose diet (from Research Diets ranging in fat from 45 - 58 % of calories as fat, 26 - 39 % carbohydrate (sucrose) and 16 % protein or control diets (10 % fat, 73 % carbohydrate, 16.4 % protein or rodent chow) for up to 16 weeks.

The goal of this protocol (written in French) is to describe the steps and quality controls to prepare new stable murine embryonic stem cells lines: ① either from wild type mouse embryos to introduce a mutation by genetic targeting or homologous recombination to get a genetically modified mouse line ② or from genetically modified mouse embryos with two aims:

Colonization of germ - free transgenic mice with genotyped Helicobacter pylori strains from a case - control study of gastric cancer reveals a correlation between host responses and HsdS components of type I restriction - modification systems.

As a control, irradiation of wild - type mice resulted in 100 % mortality after a period of 9 months after irradiation, when the mice were 11 months old (Fig. 3 ⇓ shows the survival curve of the females alone for the purpose of simplifying the discussion below); and mortality was mainly attributable to the development of T - cell lymphomas (Table 3) ⇓.

Pathological hallmarks of AD, including plaques and loss of synaptic markers, are readily apparent at nine months of age in huAPP / PS1 mice along with clear deficits in spatial memory when compared to wild type controls [7, 10, 11, 31].

Dr. Kreitzer and his team genetically modified two sets of mice so that they could control which specific type of MSN was activated.

We investigated the acquisition of peak responding in R6 / 2 mouse model of Huntington's disease and their corresponding wild type controls.

Type III - infected mice all had readily detectable parasite load, well above uninfected controls (Figure 2Ai).

The new study found that the level to which the immune systems of mice tolerated H. hepaticus is determined by the interplay of two types of T cells, which control whether the immune response to a microbe amplifies.

Methods: R6 / 2 CAG 240 (peak training at 11 weeks of age), zQ175 knock in (KI) HET (peak training at 27 weeks of age) and BAC HD (peak training at 48 weeks of age), as well as respective age - matched wild type (WT) control mice, were trained on the peak interval task (20 s interval) in which response rates during unreinforced peak trials were examined.

By controlling the neurons with optogenetics in mice, Neir Eshel studied how the dopamine neurons interact with another type of neuron: GABA - neurons.

Thus, while pathology was seen in sections from the control mice, the hypersensitivity - type pathologic reaction with eosinophils was not seen.

The level of anxiety in APPswePS1ΔE9 mice was increased according to one report [39] whereas in 7 - month - and 12 - month - old mice of the same strain, there was a reduction in anxiety compared to wild type controls [40, 41]-RRB-.

Research Interests: Molecular control of cell fate from stemness to differentiated skeletal and neuronal cell types; SOX transcription factors; skeletal malformation and degeneration diseases; intellectual disability and autism spectrum disorders; mouse genetic models; human pluripotent stem cell differentiation models in vitro

Progranulin values were generally normalized to the wild - type sedentary control group, except in Figure 4, which included only Grn + / − mice.

Wild - type littermates were used as controls for Grn + / − and Grn − / − mice.

The researchers also found that a signaling protein called type I interferon controlled the difference in T cell response in mice with this mutant polyomavirus.

The present study was aimed at identifying behavioral tests that are most sensitive to the emergence of behavioral / neurological deficits in male and female SOD1 G93A mice (SOD - 1) compared to wild - type (WT) controls.

Type I interferon directly controlled the ability of the virus to grow in mouse cells, the researchers said.

However, TPH2 − / − mice were not different from wild - type controls on any of these tests and in some cases were more resistant to the development of depression - like behaviors than wild - type controls.»

Prospective teachers also participated in surveys, controlled the instructor's computer mouse during demonstrations, and typed ideas on the interactive whiteboard.

The upcoming Adam from Notion Ink also packs something of this type, though it's only restricted to a trackpad that has been accommodated at the rear and lets you control mouse gestures by scribbling with your fingers from behind.

BlackBerry Bridge also allows the smartphone to remotely control the PlayBook with a virtual mouse (with full access to pane gestures) and typing through the handheld's keyboard.

Users can also plug in the Keyboard Folio for fast, comfortable and accurate typing and mouse control With WiFi connectivity, 2 GB of free cloud storage, a standard size USB port and SD Card Reader and Lenovo's unique file copy utility, sharing media files and documents with other people and electronic devices is easy.

You can keep playtime interesting by introducing new toys that don't involve going anywhere near your hands, such as laser pointers, remote - control mice, and «fishing pole» type toys.

Since each squad can be upgraded with a number of different weapon types, and each weapon type has a specific function in the game, properly controlling, outfitting, and reinforcing your squads in the heat of battle can be difficult just using the mouse.

The improved graphics, frame - rates and the use of mouse and keyboard for controls, is a triple - threat of flavor for a certain kind of palate; a certain type of gamer.

Anyone who prefers the mouse and keyboard controls of a PC for some game types has found a game they like on a game console and wished it had mouse and keyboard controls.

Eye Control is an «incredible eye tracking technology that lets you type, and operate a mouse just using your eyes, this is life changing technology for those with Lou Gehrig's disease.»