Sentences with phrase «type mice did»

Duke University Medical Center researchers led by Kyle Allen found that collagen deficient mice prematurely developed common and chronic musculoskeletal disorders while the wild - type mice did not.

The wild - type mice didn't develop colitis, but showed low - grade inflammation in their intestines and several features of metabolic syndrome: slight weight gain, increased body fat and food intake, and higher blood sugar levels, which indicate poor glucose regulation associated with diabetes.

At about 24 weeks, however, seventy percent of them developed spontaneous colitis, while none of the wild - type mice did.

Not exact matches

It is dominated by the far - seeing genius of Josh Boger, who at age 7 does experiments in a lab above his parents» garage (including sending a hapless mouse soaring aloft on a Hindenberg - type contraption he rigs up).

Additionally, if similar body types, e.g. density, were the primary factor then why don't we find any dolphins with sharks prior to the appearance of mammals, or mice with lizards, or birds with fish prior to land animals, or even fruits with plants prior to land animals as the Bible would have us believe?

What's more, says John Crabbe, a behavioral geneticist at the Portland Veterans Affairs Medical Center in Oregon who researches alcoholism in mice, just because an enrichment works for one type of disorder doesn't mean it should be applied to all.

A team led by biologist Rudolf Jaenisch of the Massachusetts Institute of Technology's Whitehead Institute in Cambridge did such an analysis with two types of cloned mice.

Coussens and her U.C.S.F. colleagues Douglas Hanahan and Zena Werb reported in 1999 that mice engineered with activated cancer genes but without mast cells (another type of innate immune cell) developed premalignant tissue that did not progress to full malignancy.

But when the mice were engaged in just one type of learning, humanized and wild mice did equally well on all the tests.

In the new study, Datta and his team discovered that necklace neurons in mice do not express GPCRs, unlike all other types of olfactory sensory neurons in mammals.

«These mice don't have type 2 diabetes yet, but they're not responding to insulin anymore and that state of insulin resistance is referred to as prediabetes.»

The research was done with laboratory mice that consumed different diets and then faced a variety of tests, such as water maze testing, to monitor changes in their mental and physical function, and associated impacts on various types of bacteria.

Harvard University evolutionary biologist Hopi Hoekstra, and Jesse Weber, now at the University of Texas, Austin, started with a relatively simple question: How do genes influence the types of burrows mice build?

In this study, the work was done in Type 1 diabetic mice.

In a matter of weeks, the single stem cell repopulated the mouse's blood and immune system but did not create other types of cells.

The mouse version of the IAPP protein can not clump — and mice don't develop type 2 diabetes, a sign that the accumulation of IAPP is important in the development of the disease, says Soto.

The researchers developed mice that did not have SOD1 in their muscles, though it was still present in other types of cells.

He notes, for instance, that clopidogrel helped one kind of lupus - mimicking mice even though the animals don't show high levels of type I interferons.

Further experiments identified new therapeutic options: Mice that are unable to produce Type - 1 interferon were protected against Listeria infection despite the migration of the gut bacteria into the liver, because their immune cells didn't produce high levels of Type - 1 interferon and IL - 10 after Listeria infection.

However, I did obtain a number of female Z116A transgenic mice that were heterozygous for the myostatin mutation, and as shown in Table 1 and Figure 2a, these mice exhibited further increases in muscle weights compared to Z116A mice that were wild type for myostatin.

One of the common types that infect people, Salmonella Typhimurium, doesn't usually get mice sick, so Adkins and colleagues used mice uniquely sensitive to Salmonella infection.

Kissler and his research team are using a mouse model of type 1 diabetes to see what the genes do in a living animal.

But in the other two types of mice, changes in the microbiome did not bring these positive changes in metabolism.

Young mice that expressed high levels of human amyloid - β (but did not have pathological plaques) infected in the brain with Salmonella typhimurium were more likely to survive the infection compared to wild - type mice that did not express the peptide, Tanzi, Moir, and their colleagues found.

'' (as the two independent demonstrations that resveratrol does not extend lifespan in nonobese, wild - type mice over a wide range of doses)» - Michael

Membrane resistance and rheobase in both dSPN and iSPNs from 2 - month old Q175 mice did not significantly differ from Wild - type (WT) dSPN and iSPNs respectively, suggesting that deficits in SPN excitability emerged largely in parallel in each subtype.

Interestingly, p21 - deficient mice did not develop T - cell lymphomas, which is one of the most common tumor types in p53 - null mice (36, 37, 38).

And the claim typically persists for decades once widely - cited, despite the best efforts of serious investigators to critique weak methodologies and flawed interpretation, or even robust demonstrations of a null effect in healthy animals (as the two independent demonstrations that resveratrol does not extend lifespan in nonobese, wild - type mice over a wide range of doses).»

It is interesting to note that p21 - deficient mice did not develop T - cell lymphomas, which is one of the most common tumor types in p53 - null and p19ARF - null mice (36, 37, 38, 42, 43).

With the recent development of transgenic mouse models, which allow labelling and manipulation of specific cell types, more and more emphasis has been placed on the tissue scale: How does the collective behavior of many cells gives rise to the architecture that is characteristic for given kind of tissue?

Due to the variety of generalized pathology and since detailed studies of Type II infection as it relates to mouse behavior exist elsewhere, we did not continue investigations with Type II parasites.

In contrast to our results, those studies did not find clear evidence of the Th2 type immunopathology on challenge of mice given a vector vaccine for the S protein.

Importantly, when mice received lethal doses of host - type acute leukemia cells, administration of VPA did not impair GVL activity and resulted in significantly improved leukemia - free survival.

Tang wondered if he could use previously established mouse lines expressing GFP in specific cell types to do more than just label cells.

Greater running distance in the 2 - to 3 - month - old mice may partially explain these data, but the solo - housed wild - type mice used to test solo - versus group - housing (Fig. 5) ran similar distances as the young mice, yet did not show any increase in brain progranulin levels.

Those mice were unsuccessful with context fear conditioning, but they did as well as wild - type mice when they were treated with memantine.

Wheel running for 7.5 weeks did not significantly increase any measure of progranulin in wild - type or Grn + / − mice.

Exercise (7.5 weeks) does not increase progranulin in wild - type or Grn + / − mice.

There is potential with this, if you don't want your lemon curd straight you could whip up the cream and fold in the lemon curd (i would prob start with half of what the recipe states and add more to taste) with some cream cheese to make a lemon mouse which you could then put on top of crumbled biscuits to make a cheesecake type desert as mentioned above.

The 2015 study, done at Washington State University, reported that mice that were fed a diet containing 0.1 percent resveratrol were able to convert their excess white body fat (the type that can lead to health risks) into metabolism - revving beige fat.

The researchers did experiments with a type of lab mouse that easily puts on weight and develops diabetes [TSOD].

The mice given the Nobiletin flavonoid avoided these issues, while those that did not became obese, developed type 2 diabetes, and had atherosclerosis and fatty liver issues.

Lastly you want to pay attention to what your elbows are doing while typing or using the mouse.

Probably because of the complex engineering of the folding roof, the convertible hasn't yet gotten the 2.0 treatment, so the IS - C does not have, for example, Lexus's new mouse - type computer controller or the larger dashboard screen, the eight - speed transmission, the praying - mantis grille or other up - to - the - second touches.

Whether it's the company's new touchpad or previous mouse - type contraption, Lexus» infotainment offerings have struggled with clunky interfaces for years, and it doesn't appear that'll be changing anytime soon.

If you can move a mouse, follow simple instructions, and type text into a PC, you can do this.

You can keep playtime interesting by introducing new toys that don't involve going anywhere near your hands, such as laser pointers, remote - control mice, and «fishing pole» type toys.

Fortunately, this specific type of mouse and rat poison does have a prescription antidote called Vitamin K1.

I believe at least three or four of those types of interactions could be done in one keyboard or mouse click.

Rather than just do a simple battling - type system, we created a special cat - and - mouse type game which has you and the enemy take turns as cat or mouse, either scouring the stage for the other player or running away from him.