Sentences with phrase «type mice indicate»
(Left) Blood smears from anemic mice indicate irregular shapes of red blood cells; (right) wild type mice indicate normal shapes of red blood cells.
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Sinclair thinks that these mouse models indicate that resveratrol may be effective in preventing age - related diseases in humans, like cancer, heart disease and type 2 diabetes.
Earlier mouse studies by Li and his collaborators had indicated that the expression of several imprinted genes changes as hematopoietic stem cells embark on their journey from quiescent reserve cells to multi-lineage progenitor cells, which form the many highly specialized cell types that circulate within the blood stream.
The wild - type mice didn't develop colitis, but showed low - grade inflammation in their intestines and several features of metabolic syndrome: slight weight gain, increased body fat and food intake, and higher blood sugar levels, which indicate poor glucose regulation associated with diabetes.
Additionally, when the same type of mice on the same diet for 45 weeks, at which point they would have already developed HCC, showed no signs of HCC after treatment with AIM, indicating that cancerous cells were being destroyed.
«Previous studies in mice have indicated that bacteria that are able to encroach upon the epithelium might be able to promote inflammation that drives metabolic diseases, and now we've shown that this is also a feature of metabolic disease in humans, specifically type 2 diabetics who are exhibiting microbiota encroachment.»
Using mice bred to lack some types of lymphoid cells, among other features, researchers were able to show that those mice still had high levels of suPAR and proteinuria, indicating that lymphoid cells were not the perpetrators of kidney disease.
Their study in aged mice indicates that high folic acid intake causes lowered immune function because natural killer (NK) cells, a particular type of immune cell, are less effective.
Interestingly, Nav1.1 - deficient interneuron transplants were sufficient to cause behavioral abnormalities in wild - type mice, indicating the key functional role of interneurons and Nav1.1 for cognitive functions.
Their research, the scientists suggest, indicates that the adult mouse pituitary includes two similar — but not identical — types of hormone - producing cells: some that grew in the developing embryo, and some that appeared later.
The results indicated that 54 % (38/70) of the BALB / c corneal allografts underwent rejection in the CD4 KO hosts, while 100 % of the grafts were rejected in wild - type C57BL / 6 mice (Figure 1).
These findings indicated that the same process found in type 1 diabetes - prone mice also occurs in patients with type 1 diabetes.
Analysis of transcriptomes in tumour tissues from wild - type mice and Slc6a14 - null mice indicated no compensatory changes in the expression of any other amino acid transporter mRNA.