Sentences with phrase «type mice on»

Not exact matches

Studies have found that the additive increases risk of certain types of cancer in mice and the International Agency for Research on Cancer classifies byproduct 4 - Mel as «possibly carcinogenic to humans.»

It is dominated by the far - seeing genius of Josh Boger, who at age 7 does experiments in a lab above his parents» garage (including sending a hapless mouse soaring aloft on a Hindenberg - type contraption he rigs up).

Additionally, repetitive motions like typing on a keyboard and clicking a mouse can ignite further complications down the road.

But the types of consumer behavior that internet firms can access — how long you hover your mouse on a particular item, how many days an item sits in your shopping basket before you purchase it, or the fashion blogs you visit before looking for those same items through a search engine — is uncharted ground.

Topical application of capsaicin on the dorsal skin of 7,12 - dimetylbenz (a) anthracene — initiated and TPA - promoted TRPV1 wild - type (WT) and TRPV1 knockout (KO) mice induced more and larger skin tumors in TRPV1 / KO mice, suggesting a TRPV1 - independent mechanism.

The weight of the gaming mouse will depend on a number of factors, most notably the type of materials it is constructed from.

The researchers collected samples of indoor dust from 11 homes in North Carolina and tested extracts from the samples in a mouse pre-adipocyte cell model, 3T3 - L1 cells, often used to test compounds for potential effects on the accumulation of triglycerides, a type of fat.

The researchers have already tested their invention on mice with type 1 diabetes and related acidosis.

Now, researchers at Washington University School of Medicine in St. Louis have shown, in mice, that the virus infects a rare type of intestinal cell called a tuft cell, so named because each cell sports a cluster of hairlike extensions on its surface.

By combining each mouse's genome, phenome, proteome and metabolome, the scientists were able to identify a particular gene, located on their chromosome 2, and whose presence plays an important role in the development of type 2 diabetes «The mice with a high - fat diet are more or less likely to develop diabetes depending on whether this gene is active or not,» said Evan Williams, LISP PhD student and the article's co-first author.

They focused on four different types of mice, each of which made GFP in a single type of retinal ganglion cell.

As the mice aged, their motor performance on a rotarod test (which measures how long the mouse can remain on a rotating rod) became impaired and the length of their strides were significantly shorter than the wild type control mice.

«Novel type 1 diabetes treatment shown to work on human beta cells transplanted into mice.»

Austad says other medications have shown similar effects on extending mouse life span, including acarbose (a common drug prescribed for Type 2 diabetes), and anti-inflammatory drugs such as masoprocol and basic aspirin.

A chemical produced in the pancreas that prevented and even reversed Type 1 diabetes in mice had the same effect on human beta cells transplanted into mice, new research has found.

The latest findings build on previous work by Dr. Habib's lab showing that the same combination of drugs was successful in a mouse model of glioblastoma, a deadly type of brain cancer.

«The challenge is finding targets that exist on other types of cancer cells but not on normal cells,» says pediatric oncologist Stephan Grupp of the Children's Hospital of Philadelphia, who worked with Porter on testing the treatment in mice.

A team from the University of California, San Francisco and Berkeley - based drug maker Plexxikon found that most of the mice manipulated to have Type 1 diabetes no longer had diabetes symptoms after just a few weeks on either of the two drugs.

The research of different types of cancer and the testing of new treatments depends on accurate mouse models.

«Early during pregnancy, if the mother is infected, there is significant impact on the fetus, even in wild type mice,» she noted.

Mice with two copies of this mutation (one on each chromosome) are white; those with just one copy are significantly lighter than wild - type mMice with two copies of this mutation (one on each chromosome) are white; those with just one copy are significantly lighter than wild - type micemice.

But when the mice were engaged in just one type of learning, humanized and wild mice did equally well on all the tests.

«None of the neurotrophic factor manipulations influenced amyloid deposition, while they all had effects on memory function, also in wild - type mice without amyloid beta pathology,» says Susanna Kemppainen, MSc, who presented the results in her doctoral thesis.

This is because, on treating with the antibiotic ampicillin, no inflammation was observed in wild - type SPF mice with the induction of TH1 cells as described above, but it was caused in IL (interleukin)-10-deficient SPF mice.

Knocking out a particular gene in muscle lets mice run twice as far as normal; knocking out the same gene in fat cells allows the animals to put on weight without developing type - 2 diabetes.

Earlier mouse studies by Li and his collaborators had indicated that the expression of several imprinted genes changes as hematopoietic stem cells embark on their journey from quiescent reserve cells to multi-lineage progenitor cells, which form the many highly specialized cell types that circulate within the blood stream.

Using juvenile and adolescent mice, Jeffrey Edwards and colleagues investigated the effects of tetrahydrocannabinol (THC), the chemical in marijuana responsible for its effects on cognition and behavior, on VTA GABA cells, an understudied inhibitory cell type in the reward system that regulates dopamine levels.

The research was done with laboratory mice that consumed different diets and then faced a variety of tests, such as water maze testing, to monitor changes in their mental and physical function, and associated impacts on various types of bacteria.

Among transgenic mice on the experimental diets, the mice on the Fortasyn diet performed equally well as the wild - type mice, whereas other dietary treatments showed no improvement.

For female mice — which had no such neurons to begin with — exposure to male urine had no effect on the types of neurons in their noses.

Additionally, when the same type of mice on the same diet for 45 weeks, at which point they would have already developed HCC, showed no signs of HCC after treatment with AIM, indicating that cancerous cells were being destroyed.

The software can determine whether the people are actually at their desks as well as very nuanced metrics of their computer usage, from number of words typed per minute and mouse clicks to where their eyes go on the screen.

The company tested that potential therapy, a type of protein known as a monoclonal antibody, on mice with their own form of FOP and lo and behold, they stopped growing unwelcome new bone.

In those mice, inositol triphosphate receptor type - 3 (IP3R3), a MAM - enriched calcium ion (Ca2 +) channel on ER, was disappeared from the MAM.

Sitting in her airy Jackson Lab office, accessible to germy and perturbing strangers, Chesler clicks open a series of photographs from a type of mouse personality test on her computer screen.

Depending on what type of diet was provided, broad - spectrum antibiotics, which eliminated most gut bacteria, affected hepatic inflammation differently in FXR - deficient mice.

As a basis for their experiments, the researchers drew on mouse studies that have identified key regulatory mechanisms acting within and between different cell types to coordinate developmental programs.

To test whether the childhood infection and stem cell depletion had any effect on the adult heart, the researchers exposed infected mice to two different types of cardiac stress.

Crystal hopes to improve on his team's results by using a different type of viral vector that worked much better in mice in his latest studies.

Tests on mouse models for type 1 diabetes show that one injection works for a minimum of 14 hours, during which time it can repeatedly and automatically lower blood sugar levels after mice are given amounts of sugar comparable to what they would consume at mealtime.

The scientists note that certain specialized types of cells in the liver could also have limited virus reproduction and put a damper on systemic inflammation and blood clotting problems in resistant mice.

The participants were asked to «point and click» on letters — similar to using a normal computer mouse — to type specific sentences, and their typing rate in words per minute was measured.

Tests on the mice showed that many different types of mature blood cells were making ADA.

The MIT team is now testing this approach to treat tumors in mice and is also working on ways to deliver the antibodies to specific types of cells.

In their new paper in Journal of Immunology, Mandy Ford, Craig Coopersmith and colleagues show that 2B4 levels are increased on certain types of T cells (CD4 + memory cells) in human sepsis patients and in a mouse model of sepsis called CLP (cecal ligation + puncture).

Liliana M.; El - Khodor B F.; Hornberger M.; Park, Larry; Howland, David; Brunner D. Effect of the rd1 mutation on motor performance in R6 / 2 and wild type mice [Internet].

At the highest zoom level, hovering your mouse over each star will give you the name, spectral type and luminosity of the star, and clicking on the star will bring up an information window that allows you to search for more information on that star.

Menalled L, El - Khodor B.F, Hornberger M, Park Lm Howland Dm Brunner D. Effect of the rd1 mutation on motor performance in R6 / 2 and wild type mice [Internet].

Menalled, L., El - Khodor, B. F., Hornberger, M., Park, L., Howland, D., and Brunner, D. Effect of the rd1 mutation on motor performance in R6 / 2 and wild type mice, in PLoS Currents Huntington Disease..

On the contrary, they were protected relative to wild - type mice.