Sentences with phrase «type mice suggesting»

«What we found was, if we block mGluR5, which is the glutamate receptor we're interested in, the mice become hyper locomotive so they become able to move better than wild type mice suggesting glutamate receptors might be a good target for treating movement disorders such as Parkinson's disease.

Not exact matches

Topical application of capsaicin on the dorsal skin of 7,12 - dimetylbenz (a) anthracene — initiated and TPA - promoted TRPV1 wild - type (WT) and TRPV1 knockout (KO) mice induced more and larger skin tumors in TRPV1 / KO mice, suggesting a TRPV1 - independent mechanism.

«So far, the drug has only been tested in mice, and while some research in human genetics suggests this approach could work in people too, we need more research before we know how relevant this could be for people with type 2 diabetes.»

At 60 days post-weaning — the equivalent of mouse adulthood — the LPS mice could walk well, but were still hyperactive, suggesting the motor problems had resolved, possibly through some type of rewiring of the brain, but the behavioral problems had not.

Pregnant mothers with unbalanced diets may be more likely to bear children at risk of adult type 2 diabetes, a study in mice suggests.

Studies in mouse models suggest that BL - 9020 can inhibit beta cell death in the pancreas, thus preventing full maturation of Type 1 diabetes.

The tumors in Sand's lab might be explained by the high dose, the fact that the mice were newborns, and the type of mouse, suggests Kay, who was involved with a past clinical trial administering AAV to the liver to treat hemophilia.

«This finding suggests that there are two different types of neurons, ESP1 and predator neurons, and only the former controls sexual behaviors in female mice,» explains Touhara.

Our study suggests otherwise, though, as we found that a certain type of B cell is quite abundant in the ventricles, meninges, and choroid plexus in the brains of young mice.

Mice that lost weight and then gained back more than they lost maintained an obesity - type microbiome that affected biochemicals involved in either burning or adding fat — suggesting interventions.

In addition, blood estrogen levels at late stages of pregnancy were found to be about two times higher in Nrk mutant mice than in wild - type mice, suggesting that Nrk is also involved in the regulation of synthesis or secretion of estrogen.

The DNA of BKV has been discovered in several types of human cancers including prostate tumours, and mouse studies suggest the virus can trigger cancer.

Their research, the scientists suggest, indicates that the adult mouse pituitary includes two similar — but not identical — types of hormone - producing cells: some that grew in the developing embryo, and some that appeared later.

The study of mice suggests that a high - fat diet drives a population boom of intestinal stem cells and also generates a pool of other cells that behave like stem cells — that is, they can reproduce themselves indefinitely and differentiate into other cell types.

Membrane resistance and rheobase in both dSPN and iSPNs from 2 - month old Q175 mice did not significantly differ from Wild - type (WT) dSPN and iSPNs respectively, suggesting that deficits in SPN excitability emerged largely in parallel in each subtype.

However, challenge of mice given any of the vaccines led to occurrence of Th2 - type immunopathology suggesting hypersensitivity to SARS - CoV components was induced.

Induced pluripotent stem cells have the potential to become any cell type; recently, this ability was used to generate retinal cells that were shown to rescue vision in blind mice, suggesting these cells could also be potentially used to treat blindness in humans.

An experimental oral drug has lowered blood sugar levels and inflammation in mice with Type 2 diabetes, suggesting that the medication could someday be added to the arsenal of drugs used by millions of Americans with this disease, according to new research.

«What this might suggest is that transfer of some of the «good» microbiota from wild - type mice to replace the «bad» microbiota from mice lacking AIM2 offers increased protection against colorectal cancer,» Man said.

However, one study which analyzed data from humans and genetically modified mice suggested that the LYP variant associated with type 1 diabetes is a loss - of - function mutation that reduces LYP activity.

Expression is in the same cell types (spermatocytes and spermatids) in the testes of the human, mouse and fish medaka, suggesting conservation of developmentally - regulated testicular expression of Boule in vertebrate animals [35], [53].

Test - tube studies have found that asparagus may help stop the growth of several types of cancer, and studies in mice suggest it may help protect brain health and reduce anxiety (10, 11, 12, 13,14).

CONCLUSION: The results suggest that alpha - lipoic acid can increase glucose uptake by a range of normal muscle types and improve the response to insulin by insulin - resistant skeletal muscles of ob / ob mice.

Effects of Alpha - lipoic Acid on Microcirculation in Patients with Peripheral Diabetic Neuropathy Diabetes Obes Metab 2002 (Jan); 4 (1): 29 — 35 The results suggest that alpha - lipoic acid can increase glucose uptake by a range of normal muscle types and improve the response to insulin by insulin - resistant skeletal muscles of ob / ob mice.