Sentences with phrase «type mice when»

Those mice were unsuccessful with context fear conditioning, but they did as well as wild - type mice when they were treated with memantine.

Not exact matches

When the team analysed the gut bacteria present before and after the experiments, they saw an increase in several different types of bacteria in the mice that consumed sweeteners.

Specifically, the researchers found that a peptide, called STAT6 - IP, when delivered to the lungs of neonatal mice at the time of first RSV exposure reduces the development of allergic - type lung inflammation and airway hyperresponsiveness («twitchy» airways) in mice when they are «re-challenged» with RSV as young adults.

However, in some studies with laboratory mice, Feinberg had observed that these epigenetic tags varied considerably among the mice even when comparing the same type of tissue in animals that have been living in the exact same conditions.

Homozygous mice carrying a null mutation for the DARPP - 32 gene exhibited minimal levels of P - facilitated sexual receptivity when compared to their wild - type littermates.

This summer Wagers published research [subscription required] showing that when muscle stem cells were transferred into mice with a type of muscular dystrophy, the rodents» muscle function improved.

The researchers discovered that both types of cells shut down when the mice were infected with malaria.

Activated, wild type B cells from female mice tightly localize Xist RNA at their inactive X chromosomes (left), whereas Xist RNA becomes dispersed throughout the entire nucleus when YY1 is deleted (right).

The patch, which feels like a mosquito bite when applied, has already proved effective in mouse models with type 1 diabetes for up to 9 hours, scientists report online before print in the Proceedings of the National Academy of Sciences.

One of the defects is an error in mouse t - RNA (another type of RNA involved in translation) that stalls the ribosome and the other is a defect in the system that rescues the ribosome when it stalls.

But when the mice were engaged in just one type of learning, humanized and wild mice did equally well on all the tests.

When scientists reported 2 years ago that mice with certain gut bacteria responded best to a powerful new type of cancer drug, other researchers were intrigued but cautious — mice, after all, aren't humans.

When the scientists blocked Treg cells from accumulating in the fat by targeting a molecule that the immune cells require, mice no longer developed type 4 diabetes in old age.

«But what was really surprising was that when obese mutant mice were given metformin, the most common and inexpensive drug prescribed to Type 2 diabetics, the drug failed to lower their blood sugar levels,» said Steinberg.

When the team injected RNA for the TALENs enzymes into mouse eggs that contained two varieties of mitochondrial DNA, it similarly reduced the levels of one type.

Additionally, when the same type of mice on the same diet for 45 weeks, at which point they would have already developed HCC, showed no signs of HCC after treatment with AIM, indicating that cancerous cells were being destroyed.

When the deformed pancreas proteins were injected into mice without type 2 diabetes, the animals developed symptoms of the disease, including overly high blood sugar levels, the researchers report online August 1 in the Journal of Experimental Medicine.

When the researchers altered the animals» eating patterns by feeding normal mice only during the light cycle (a mouse's night), the numbers, types, and activity of the bacteria shifted as well.

When mice were immunized with the vaccine, they produced a 50-fold higher concentration of the potent IgG - type antibodies as compared to mice injected with the standard polysaccharide vaccine.

A team led by parasitologist Stefan Kappe at the Center for Infectious Disease Research in Seattle in Washington gave a rodent version of this «genetically attenuated parasite,» or GAP, to mice and showed that they were completely protected when later infected with an unmodified — or wild - type — version of the same Plasmodium strain.

The epithelial stem cells, when implanted into immunocompromised mice, regenerated the different cell types of human skin and hair follicles, and even produced structurally recognizable hair shaft, raising the possibility that they may eventually enable hair regeneration in people.

The researchers have identified a protein — RbAp48 — that, when increased in aged wild - type mice, improves memory back to that of young wild - type mice.

In mouse models, carcinogen - induced tumors that arise in immunodeficient mice, when transplanted to wild - type mice, are usually eliminated by the intact immune system of the new host.

In contrast, tumors induced in wild - type mice often grow when transplanted to other wild - type mice.

The new iPS cells passed the standard tests for pluripotency: They formed tumors called teratomas when injected into immunocompromised mice, and they could differentiate into cells from the three main tissue types in the body, including neurons, muscle and gut epithelium.

As a control, irradiation of wild - type mice resulted in 100 % mortality after a period of 9 months after irradiation, when the mice were 11 months old (Fig. 3 ⇓ shows the survival curve of the females alone for the purpose of simplifying the discussion below); and mortality was mainly attributable to the development of T - cell lymphomas (Table 3) ⇓.

They found that when an MS - like disease was induced in mice genetically engineered to be deficient in Tob1, the mice had significantly earlier onset compared with wild - type mice, and developed a more aggressive form of the disease.

In contrast, the same cells transplanted to immunocompromised mice remained highly immunogenic; eight of ten are still eliminated when transplanted to wild - type mice (regressor clones).

Pathological hallmarks of AD, including plaques and loss of synaptic markers, are readily apparent at nine months of age in huAPP / PS1 mice along with clear deficits in spatial memory when compared to wild type controls [7, 10, 11, 31].

Interestingly, when parental d42m1 sarcoma cells were transplanted into wild - type mice, around 20 % of recipients developed «escape» tumors which evaded immune destruction and progressed (escape clones).

When transplanted into wild - type mice with intact immune systems, these tumors are eliminated, presumably by T - cells.

Moreover, the iPS cells can spontaneously differentiate or be induced into various cell types of three embryonic germ layers in vitro and in vivo when they are injected into immunodeficient mice for teratoma formation.

These reagents, prepared against human light chain - related fibrils, recognize an epitope common to the beta - pleated structure of AL and other types of amyloid proteins and can effect rapid amyloidolysis when administered to mice injected with human AL amyloid extracts.

Importantly, when mice received lethal doses of host - type acute leukemia cells, administration of VPA did not impair GVL activity and resulted in significantly improved leukemia - free survival.

When transplanted into mice, the neural stem cells spontaneously developed into the three basic types of brain cells: neurons, oligodendrocytes, and astrocytes.

When homozygous C57BL / 6 - Fabp 4 - knockout mice (B6 - Fabp4 - / --RRB- are fed a high fat diet, they gain even more weight than wild - type B6 DIO mice.

However, when researchers fed the mice a nondigestible prebiotic fiber called oligofructose (a type of inulin), it shifted their gut microbiome to reduce inflammation protect from osteoarthritis despite no change in body weight.

When supplements of NAC, vitamins C and E or both were given to Type 2 diabetic mice, retained insulin secretions and decreased blood glucose levels were observed (23).

Depending on the type of tapeworm, puppies become infected with them when they swallow fleas or when they eat contaminated raw meat or infected mice, birds or rabbits.

When you compare this type of input to a similar retro product like the mouse that came bundled with Mario Paint on the Super Nintendo, you can see that we have come a long way in terms of technology.

To create a document, the user simply chooses a document type from the menu, fills in document - specific questions when prompted (e.g., specific dates and text) and with a single mouse click produces a Microsoft Word document that can be proofread, edited and saved.

Now when you type any alphabet using your key board, where does the focus and your mouse pointer jump to?

the trackpad is being used to move the mouse cursor, on the new iPad Pro this new feature could be used to move the cursor when typing, similar to what you can do right now with 3D Touch on iOS.

If you choose the latter file type, you can use Adobe Acrobat Reader to add links in the infographic or other marketing collateral you created so when those browsing your design mouse over the visual, they can click a relevant link that leads them back to your site.

Still some mice type and I can't change it, but most of it is good when read on a computer.