The present findings are derived from studies using CD4KO mice and thus, raise the question as to whether the CD4 + T cell - independent immune mechanisms in CD4 KO mice differ from those involved in corneal allograft rejection in wild -
type mice whose CD4 + T cells population have been depleted with monoclonal antibodies.
Not exact matches
By combining each
mouse's genome, phenome, proteome and metabolome, the scientists were able to identify a particular gene, located on their chromosome 2, and
whose presence plays an important role in the development of
type 2 diabetes «The
mice with a high - fat diet are more or less likely to develop diabetes depending on whether this gene is active or not,» said Evan Williams, LISP PhD student and the article's co-first author.
The researchers injured the
mice retinas with a toxin that causes cell death in retinal ganglion cells and interneurons, another
type of retinal cell
whose job it is to transmit signals from photoreceptors to the brain.
To test whether the cells would maintain their multipotency in living animals, the researchers transplanted them into
mice whose white blood cells had been depleted, and showed that the new cells could expand and differentiate into various
types of white blood cells.
This
type of eating plan has shown promise in animal studies;
mice who are fed time - restricted diets tend to lose more body fat and have lower risk of chronic diseases than those
whose meals are more spaced out.
Even for those
whose work is done mostly with a computer keyboard, an injury to the neck, back or shoulders may make
typing and using a computer
mouse too painful to continue.