Sentences with phrase «type mice with»

We tested this hypothesis by housing 2 - month - old wild - type mice with or without running wheels for 3 — 4 weeks.

When transplanted into wild - type mice with intact immune systems, these tumors are eliminated, presumably by T - cells.

What surprised us most was that the virus replicated in the vagina of wild - type mice with intact interferon response,» said Iwasaki.

This study, «Engineered epidermal progenitor cells can correct diet - induced obesity and diabetes,» is the first to show that an engineered skin graft can survive long term in wild - type mice with intact immune systems.

Not exact matches

Additionally, if similar body types, e.g. density, were the primary factor then why don't we find any dolphins with sharks prior to the appearance of mammals, or mice with lizards, or birds with fish prior to land animals, or even fruits with plants prior to land animals as the Bible would have us believe?

And for that audience, providing that type of analysis with two or three mouse clicks is great.

In the new work, published June 10 in the journal Scientific Reports, Zhao, Reid and colleagues used a highly sensitive probe to measure electrical fields in the corneas of isolated eyes from three different lab mouse models with different types of diabetes: genetic, drug - induced and in mice fed a high - fat diet.

We have researched a ton of different products with all types of games (from FPS and RTS to Roleplaying and MMORPG) and picked the best cheap gaming mouse (well, to be honest, the ten best gaming mice).

A new mouse model of a genetically - linked type of autism reveals more about the role of genes in the disorder and the underlying brain changes associated with autism's social and learning problems.

We have now shown in mice that the reticular thalamus contains at least two different types of neurons, each with distinctive properties, roles, and locations.»

Not every mouse will support both Windows and Mac operating systems, so ensure that the one you buy works with the type of computer or laptop you have.

A study with mice finds that the types of intestinal bacteria an individual carries can influence behavior.

To establish whether environmental changes could improve learning ability the team put mice with significant neuronal damage in one of two types of cages.

Scientists at Duke Health who developed the new model also discovered that targeting a brain receptor in mice with this type of autism could ease repetitive behaviors and improve learning in some animals.

The researchers have already tested their invention on mice with type 1 diabetes and related acidosis.

For this study the researchers targeted very specific types of GABA receptors to improve social behaviors with clonazepam, but the team also found that by using a different drug, they could target other GABA receptors and actually reduce the ability to socially interact in normal mice — underscoring that future medications would need to target very specific receptors so as not to diminish the drug's impacts.

Specifically, the researchers found that a peptide, called STAT6 - IP, when delivered to the lungs of neonatal mice at the time of first RSV exposure reduces the development of allergic - type lung inflammation and airway hyperresponsiveness («twitchy» airways) in mice when they are «re-challenged» with RSV as young adults.

In a study published in Nature Communications, the investigators report that hyperglycemic mice (or mice with type 2 diabetes) have a 24-fold higher accumulation of succinate, an intermediate metabolite, in the metabolic pathways of their bone marrow stromal cells.

«So far, the drug has only been tested in mice, and while some research in human genetics suggests this approach could work in people too, we need more research before we know how relevant this could be for people with type 2 diabetes.»

By combining each mouse's genome, phenome, proteome and metabolome, the scientists were able to identify a particular gene, located on their chromosome 2, and whose presence plays an important role in the development of type 2 diabetes «The mice with a high - fat diet are more or less likely to develop diabetes depending on whether this gene is active or not,» said Evan Williams, LISP PhD student and the article's co-first author.

However, in some studies with laboratory mice, Feinberg had observed that these epigenetic tags varied considerably among the mice even when comparing the same type of tissue in animals that have been living in the exact same conditions.

They compared the concentrations of proteins in the retinas of non-diabetic mice, of mice with type 2 diabetes without treatment and of type 2 diabetic mice that were treated with the standard drug metformin, which lowers blood glucose levels and thus reduces diabetes complications.

Bullied mice showed many more bouts of paradoxical sleep, resembling the type of sleep disruptions often seen in people with depression.

In the Cell study, Dr. Massagué, with Fellow Manuel Valiente, PhD, and other team members, found that in mouse models of breast and lung cancer — two tumor types that often spread to the brain — many cancer cells that enter the brain are killed by astrocytes.

Northwestern Medicine scientists have identified a small RNA molecule called miR - 182 that can suppress cancer - causing genes in mice with glioblastoma mulitforme (GBM), a deadly and incurable type of brain tumor.

«It's very difficult to produce a mouse model of a solid tumor of the type we see in most women who are diagnosed with cervical cancer.

This summer Wagers published research [subscription required] showing that when muscle stem cells were transferred into mice with a type of muscular dystrophy, the rodents» muscle function improved.

The researchers studied mice with a defective type of thyroid hormone receptor, meaning that they are hypothyroid in certain tissues, including in the smooth muscle of blood vessels.

Géléoc and colleagues at Boston Children's Hospital studied mice with a mutation in Ush1c, the same mutation that causes Usher type 1c in humans.

The researchers discovered that in brain regions involved in regulating anxiety — the amygdala and prefrontal cortex — microbe - free mice had an overabundance of some types of microRNA and a shortage of others compared with normal mice.

In research published last year with one of her graduate students, Katherine Motyl, she tested whether leptin could help mice avert the bone loss that can accompany type 1 diabetes.

In addition to looking at mouse models of diabetes, the researchers also showed that exposure of human pancreatic islet cells — both from healthy donors and from patients with Type 1 diabetes — to fasting - mimicking diet in a dish stimulated insulin production.

Pregnant mothers with unbalanced diets may be more likely to bear children at risk of adult type 2 diabetes, a study in mice suggests.

The researchers discovered that both types of cells shut down when the mice were infected with malaria.

What's more, human feces share 17 types of microRNAs with the mice, which may portend similar mechanisms in humans, the researchers found.

The study first examined how mice in which almost all beta cells were destroyed — similar to humans with type 1 diabetes — responded to injections of caerulein.

Ronald Kahn and his colleagues at Harvard Medical School in Boston compared gene expression in brain samples from mice with type 1 or type 2 diabetes against those of healthy mice.

In this study, the researchers used two groups of mice with different types of colitis, chronic and acute.

In the mice that consumed either type of tea extract, there was less of the type of bacteria associated with obesity and more of the bacteria associated with lean body mass.

«The challenge is finding targets that exist on other types of cancer cells but not on normal cells,» says pediatric oncologist Stephan Grupp of the Children's Hospital of Philadelphia, who worked with Porter on testing the treatment in mice.

Then the researchers looked at the way those strains behaved in mice, ferrets and monkeys compared with two other types of H7N9: a less infectious version that first emerged in 2013 and the one isolated from the patient in 2016.

The researchers mated female mice unable to make the receptor for type I interferons to males with one copy of the gene needed to make the receptor.

The researchers also infected pregnant mice that had the receptor for type I interferons with a viral mimic — a bit of genetic material that goads the body to begin its antiviral immune response — to see if the damage happened only during a Zika infection.

In a paper published in Nature Immunology in 2011, Dr. Rostami and colleagues showed that the Th - 17 cells also produced another cytokine called GM - CSF, which created a chain reaction with another cell type ultimately increasing the GM - CSF levels in the brain of mouse models significantly.

A team led by biologist Rudolf Jaenisch of the Massachusetts Institute of Technology's Whitehead Institute in Cambridge did such an analysis with two types of cloned mice.

Other types of bacteria that cause skin infection, such as Streptococcus pyogenes, were also found in lower quantities in the infected mice after they were treated with TSLP.

Desgrosellier said the team will follow up with mouse models containing tumor fragments from patients to better reflect the diversity of cell types present in human disease.

The patch, which feels like a mosquito bite when applied, has already proved effective in mouse models with type 1 diabetes for up to 9 hours, scientists report online before print in the Proceedings of the National Academy of Sciences.

They treated HIV - infected mice with antibodies that blocked type I interferons, which allowed the mice's immune systems to revert from the state of exhaustion.

Mice with two copies of this mutation (one on each chromosome) are white; those with just one copy are significantly lighter than wild - type mMice with two copies of this mutation (one on each chromosome) are white; those with just one copy are significantly lighter than wild - type micemice.