Sentences with phrase «type mice without»

«None of the neurotrophic factor manipulations influenced amyloid deposition, while they all had effects on memory function, also in wild - type mice without amyloid beta pathology,» says Susanna Kemppainen, MSc, who presented the results in her doctoral thesis.

Not exact matches

They compared the concentrations of proteins in the retinas of non-diabetic mice, of mice with type 2 diabetes without treatment and of type 2 diabetic mice that were treated with the standard drug metformin, which lowers blood glucose levels and thus reduces diabetes complications.

More inflammatory - type T cells and less tolerant - type T cells were found in the colon of mice without gp96 as compared to wild - type mice.

Coussens and her U.C.S.F. colleagues Douglas Hanahan and Zena Werb reported in 1999 that mice engineered with activated cancer genes but without mast cells (another type of innate immune cell) developed premalignant tissue that did not progress to full malignancy.

Knocking out a particular gene in muscle lets mice run twice as far as normal; knocking out the same gene in fat cells allows the animals to put on weight without developing type - 2 diabetes.

In the new work, the researchers fed two common emulsifiers, CMC and polysorbate 80, to both a genetically susceptible mouse strain and wild - type mice — those without genetic mutations that would put them at increased risk of IBD or metabolic syndrome.

«While the «normal» mice exposed to stress exhibited high histamine levels and disease, the mice without CRF1 had low histamine levels, less disease and were protected against both types of stress,» Moeser said.

When the deformed pancreas proteins were injected into mice without type 2 diabetes, the animals developed symptoms of the disease, including overly high blood sugar levels, the researchers report online August 1 in the Journal of Experimental Medicine.

They sequenced microbe - specific genes collected from the animals» stool to determine the gut microbiome makeup of each mouse type, with or without blocked gastric acid production.

Separately, both types of mice got «sham» procedures without the electrical pulse as controls.

Metabolic syndrome without obesity: hepatic overexpression of 11ß - hydroxysteroid dehydrogenase type 1 in transgenic mice.

We tested this hypothesis by housing 2 - month - old wild - type mice with or without running wheels for 3 — 4 weeks.

GF mice raised in sterile incubators without any exposure to microbes are leaner than their wild - type, conventionally raised counterparts, despite consuming more food (1).

It lets users move the mouse cursor without lifting a hand away from a typing position.

A click of the mouse relocates the user to the intended search area — Houston, Texas — where the 3,679 homes for sale within the boundaries of the «Houston Independent School District» are served up without the user having typed in the school district's correct name.