Sentences with phrase «type of activation»

The drawback to this type of activation, however, is that it is only available on higher - end phones right now, although more phones are starting to get the feature.

Not exact matches

CRAC channels are found on many cell types, including immune cells and pancreatic acinar cells, where aberrant activation of these channels is thought to play a key role in the pathobiology of acute pancreatitis.

Hip Stabilizer Activation Exercise (backside)-- This will be some type of hip bridge to wake up the often - dormant gluteus maximus (butt) and develop motor control.

Based on the pattern of activation of the various receptor types, when I sniff Nugget Nectar, I recognize it as «beer».

Frequent, low - dose chemotherapy regimens avoid this effect and may therefore be more effective at treating certain types of breast and pancreatic cancer, according to the murine study «Metronomic chemotherapy prevents therapy - induced stromal activation and induction of tumor - initiating cells,» which will be published online November 23 in The Journal of Experimental Medicine.

Murphy found that the normal pattern of gene activation seen in aging wild - type C. elegans was reversed in the body cells and oocytes of IGF - 1 mutants.

This program, resulting in shorter 3 ′ UTRs, is a characteristic of gene expression during immune cell activation and correlates with proliferation across diverse cell types and tissues.

Understanding which cytokines are best for monitoring inflammation and immunosuppression, and knowing which are secreted by different immune cell types at each stage of maturation and activation, will provide essential insights into disease treatment options.

• Given the fact that normal cells possess wild - type p53 function, FL118 - induced p53 activation might explain the favorable toxicology profile of FL118: highly toxic to cancer cells but not so in healthy animal cells, and these different consequences might be mediated through p53 activation.

Rutgers University scientists have discovered the three - dimensional structure of a gene - specific transcription activation complex, providing the first structural and mechanistic description of the process cells use to turn on, or activate, specific genes in response to changes in cell type, developmental state and environment.

To determine whether early postnatal immune system activation can produce these types of effects, McLean researchers treated mice with a lipopolysaccharide (LPS), a chemical that simulates a bacterial infection and causes a temporary (1 - 3 day) activation of the immune system.

«While there are clearly other factors that can cause these types of abnormalities, including genetic vulnerabilities, demonstrating that immune activation alone can produce these effects offers new hope for treatments that might reduce their severity, or prevent them altogether, in certain individuals.»

Importantly, deleting these regions affected the response of vitamin D activation to hormones, but not to inflammation - related molecules, indicating that these regions were key to allowing researchers to separately study the two types of calcitriol production.

«Developing a new vaccination strategy against AIDS: The type of vaccine administered and the activation of the body's own immune cells influence the vaccine protection.»

The data show that the order and type of administration (oral spray or injection) of the vaccines may affect the activation of the immune system and may have a long lasting effect that affects subsequent immunizations as well as the susceptibility to infection.

Using the properties of the atrial activation and the signals, they were able to develop a method which can pin down the location of Atrial Fibrillation non-invasively, as well identifying different types of the condition.

Dario C. Altieri, M.D., Wistar's President and CEO and lead author of the study, and colleagues showed how the activation of this pathway leads to an unfavorable prognosis for patients with gliomas — a type of brain tumor — and how the pathway could be a valuable therapeutic target in cancer.

The activation of this signaling pathway progressively increased in different types of gliomas, with the highest activity seen in patients with glioblastoma, a particularly difficult - to - treat form of brain cancer that represents approximately 15 percent of all brain tumors.

The balance of expression of mutant and wild - type ACVR1 protein is likely to affect ligand binding dynamics, receptor oligomerization, internalization, and / or activation of downstream signaling pathways, as well as receptor response to environmental triggers that are clinical features of the natural history of FOP.

Current working model of effector activation and feedback mechanisms in type I interferon signaling.

Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF - 3 and CBP / p300.

A dynamic assembly of diverse transcription factors integrates activation and cell - type information for interleukin 2 gene regulation.

Activation of both protein kinase A (PKA) type I and PKA type II isozymes is required for retinoid - induced maturation of acute promyelocytic leukemia cells.

Next, the scientists want to test which types of memory and learning may be selected for by the activation of gatekeeper cells.

References 24 and 25 describe the positive - feedback regulation of type I IFN gene induction, which involves the expression and activation of IRF7.

Human T - cell leukemia virus type I Tax induces the expression of dendritic cell markers associated with maturation and activation.

The SDF - 1 / CXCR4 interaction stimulates tyrosine phosphorylation of CXCR4, followed by the activation of multiple G protein - dependent signaling pathways, which may be different among cell types.

Coligation of the B cell receptor with complement receptor type 2 (CR2 / CD21) using its natural ligand C3dg: activation without engagement of an inhibitory signaling pathway.

Cellular entry of human papillomavirus type 16 involves activation of the phosphatidylinositol 3 - kinase / Akt / mTOR pathway and inhibition of autophagy.

In one of the experiments, for example, activation of a particular signal at the correct time elicits the appearance of the mesoderm, endoderm and ectoderm — the precursors of all cell types — with a spatial organization similar to that of an embryo.

FOXA1 activation, inducing enhancer reprogramming that endows a cancer cell with metastatic properties, is an epigenetic mechanism, as opposed to a genetic one, that explains at least one mechanism of metastasis in this form of pancreatic cancer, and likely, other cancer types as well.

Increased MAPK activation and impaired insulin signaling in subcutaneous microvascular endothelial cells in type 2 diabetes: the role of endothelin - 1

These findings suggest that activation of mTOR signaling contributes to tumor cell survival in ALK + ALCL, thus providing a potential therapeutic target in this lymphoma type.

Although 4 - 1BB was originally thought to be only expressed after activation of conventional CD4 and CD8 T cells, it is constitutive (NK cells) or induced (NKT cells, dendritic cells) on other cell types.

Cellular senescence is often fueled by nuclear DNA damage followed by chronic DDR activation; telomere shortening, mitogenic oncogenes, or intrinsic DNA damage can lead to different types of senescence limiting the replicative lifespan of cells.

This prevents activation of genes, so this is therefore an exclusion type regulation where insulin signaling leads to prevention of gene activation by Fox01.

Moreover, these ATP - competitive inhibitors induce the formation of B - RAF and C - RAF dimers, leading to extracellular signal — regulated kinase (ERK) activation in diverse cancer cell types (23).

Recent studies indicated that autoimmune diseases like Type 1 Diabetes (T1D) are induced by genetic or environment - induced alterations of immune regulatory pathways whose function is to avoid or limit the activation / expansion of self - reactive T lymphocytes.

(D) Magnification of structure of the activation loop showing the side chains of the residues at positions 1026 and 1035 for the wild - type JAK1 (top panel), the K1026E mutant (middle panel), and the Y1035C mutant (lower panel).

The second most common mutation type in the FLT3 gene is a Tyrosine Kinase Domain (TKD) point mutation in the codon for an aspartate (D835) or an isoleucine (I836) residue that is located in the activation loop of the FLT3 protein.

Structural biologists obtained snapshots of the activation of an important type of brain - cell receptor...

The gene expression analysis suggests that activation of cell - type specific cationic channels may underlie the toxicity of the drug.

Zhao, L., Birdwell, D. Wu, A., Elliott, R., Rose, K., Phillips, J., Li, Y., Grinspan, J., Silverman, R., and Weiss, S. Cell type specific activation of the OAS - RNase L pathway by a murine coronavirus.

Read the full article, «Resistance training recovers attenuated APPL1 expression and improves insulin - induced Akt signal activation in skeletal muscle of type 2 diabetic rats,» published ahead of print in the American Journal of Physiology — Endocrinology and Metabolism.

Single amino acid mutations in mTOR are found in several types of human cancers, which confer constitutive activation of this autophagy negative regulator [10,11].

Of note, certain types of cancer cell, including pancreatic and lung cancer cells, are heavily reliant on growth benefits brought by autophagy activation, therefore becoming «addicted» to autophagOf note, certain types of cancer cell, including pancreatic and lung cancer cells, are heavily reliant on growth benefits brought by autophagy activation, therefore becoming «addicted» to autophagof cancer cell, including pancreatic and lung cancer cells, are heavily reliant on growth benefits brought by autophagy activation, therefore becoming «addicted» to autophagy.

These techniques combine traditional meditation with behavioral activation, a type of therapy that uses an «outside in» approach to help people change the way they act and aims to increase rewarding experiences in their lives.

This type of training volume and duration increases the neural activation and slightly increases the body temperature, warming up the body just enough for the upcoming workout.

In an average person who's not following that type of diet, however, anytime I see an elevated HDL, it usually, and I don't like the word inflammation, but that's the first thing that comes to mind, is some kind of inflammation, a better phrase would be immune activation.

A high intensity training type of regimen where you're doing like a long, slow movement to get muscle activation or to get HGH, where you're doing interval stuff.