Not exact matches
This
type of cancer begins when abnormal
cells in the
breast ducts divide and multiply quickly.
Molecular characterization
of the
cells that undergo
cell fate transition upon oncogenic Pik3ca expression demonstrated a profound oncogene - induced reprogramming
of these newly formed
cells and identified gene expression signatures, characteristic
of the different
cell fate switches, which was predictive
of the
cancer cell of origin, tumour
type and clinical outcomes in women with
breast cancers.
In the
Cell study, Dr. Massagué, with Fellow Manuel Valiente, PhD, and other team members, found that in mouse models
of breast and lung
cancer — two tumor
types that often spread to the brain — many
cancer cells that enter the brain are killed by astrocytes.
The researchers studied triple - negative
breast cancer cells, which grow and spread faster than most other
types of cancer cells.
In their latest study, they tested compounds against
cells from nine different
types of human
cancer, including common
types affecting blood, colon,
breast, prostate, ovaries, kidneys, and lungs.
Frequent, low - dose chemotherapy regimens avoid this effect and may therefore be more effective at treating certain
types of breast and pancreatic
cancer, according to the murine study «Metronomic chemotherapy prevents therapy - induced stromal activation and induction
of tumor - initiating
cells,» which will be published online November 23 in The Journal
of Experimental Medicine.
The data that the
breast cancer cells spread more successfully in clumps are compelling, D'Souza - Schorey said, but no one yet knows whether
cells from other
types of cancer also need help to migrate.
The study published in
Cancer Cell shows that exosomes from tumor cells of breast cancer (and other tumor types such as ovarian and endometrial) are different in size and composition than those of healthy
Cancer Cell shows that exosomes from tumor
cells of breast cancer (and other tumor types such as ovarian and endometrial) are different in size and composition than those of healthy
cancer (and other tumor
types such as ovarian and endometrial) are different in size and composition than those
of healthy
cells.
A COMPOUND that slows the proliferation
of triple - negative
breast cancer cells in lab tests could lead to the first drugs to target this aggressive
type of tumour.
Beyond lung
cancer, TiY is able to target TICs in 28
types of human
cell lines derived from the central nervous system, melanoma,
breast, renal, ovarian, colon, and prostate
cancer.
In earlier studies involving animal models and human
cancer cell lines, researchers found that
breast cancer spreads when three specific
cells are in direct contact: an endothelial
cell (a
type of cell that lines the blood vessels), a perivascular macrophage (a
type of immune
cell found near blood vessels), and a tumor
cell that produces high levels
of Mena, a protein that enhances a
cancer cell's ability to spread.
In animal and
cell culture studies, the drug inhibited growth both in estrogen - dependent
breast cancer cells and in
cells that had developed resistance to the anti-estrogen tamoxifen and / or to the aromatase inhibitors, two
of the most widely used
types of drugs to prevent and treat estrogen - dependent
breast cancer.
«Women with this
type of breast cancer also frequently develop metastatic lesions that originate from drug - resistant
cells.
Navin's team developed Nuc - Sec as a single -
cell genome sequencing method and applied it to study how
cell mutations occur in both
types of breast cancer.
His research on attaching selenium to the leading clinical chemotherapeutic monoclonal antibody for a
type of breast cancer shows it can more effectively kill the
cancer cells, he reports.
Neil Johnson's lab at the Fox Chase
Cancer Center examined treatment resistance in breast cancer cells expressing the same BRCA1185delAG mutation and determined that the RING - deficient BRCA1 protein was also responsible for loss of sensitivity to certain types of cancer treat
Cancer Center examined treatment resistance in
breast cancer cells expressing the same BRCA1185delAG mutation and determined that the RING - deficient BRCA1 protein was also responsible for loss of sensitivity to certain types of cancer treat
cancer cells expressing the same BRCA1185delAG mutation and determined that the RING - deficient BRCA1 protein was also responsible for loss
of sensitivity to certain
types of cancer treat
cancer treatments.
Previous in vitro studies conducted by researchers in other countries showed that this molecule was able to reduce the multiplication and increase the mortality
of cells from melanoma, the most aggressive
type of skin
cancer, as well as
breast cancer and neuroblastoma, a tumor that typically affects patients aged 15 or younger.
The 5E5 antibody recognized multiple
types of cancer cells, including leukemia, ovarian,
breast, and pancreatic
cancer cells, but not normal tissues.
The screening revealed coibamide A to be capable
of killing many
types of cancer cells, but Ishmael decided to focus subsequent studies on two
types in particular — brain tumors, or glioblastomas, and a
breast cancer subtype known as triple negative
breast cancer.
A new study shows coibamide A has potent anti-
cancer activity in mice and
cell cultures that model brain tumors and triple negative
breast cancer, two
of the most aggressive and difficult - to - treat
types of cancer.
Different
types of tumors show a preference for specific organs and tissues; circulating
breast cancer cells, for example, are likely to take root in bones, lungs, and the brain.
Dr. David Gilley's laboratory at the Indiana University School
of Medicine in Indianapolis and Dr. Connie Eaves» laboratory at the BC
Cancer Agency's Terry Fox Laboratory in Vancouver, Canada, collaborated to determine how telomeres are regulated in different
types of normal
breast cells.
The team found evidence
of the process in several other
cell types, including
breast, ovarian, umbilical cord, and kidney
cancer cells.
A research team, led by Chao Cheng, Ph.D., Assistant Professor in the Department
of Genetics at The Geisel School
of Medicine at Dartmouth, used gene expression data from
breast cancer patients to computationally infer the presence
of different
types of immune
cells.
Depending on characteristics such as how many tumor
cells, blood vessel
cells, and immune
cells are touching each other, the tumor microenvironment can nearly triple the chance that a common
type of breast cancer (estrogen - receptor positive / HER2 negative) that has reached the lymph nodes will also metastasize, Condeelis and colleagues showed in a 2014 study
of 3,760 patients.
Expression
of Snail represses expression
of E-cadherin and induces EMT in different
cell types, including
breast cancer cells [36, 37].
-- discovery awarded international science prize Researcher Allison Cleary has, for the first time, demonstrated that different
types of tumor
cells cooperate in the development and growth
of breast cancer.
Researcher Allison Cleary has, for the first time, demonstrated that different
types of tumor
cells cooperate in the development and growth
of breast cancer.
Invasive lobular carcinoma, or ILC, is an uncommon
type of breast cancer that begins in the milk - producing lobule
cells and invades (spreads) deeper into the
breast tissue.
Ductal carcinoma in situ, or DCIS, is a
type of breast cancer that begins in the duct
cells.
The existence
of cancer stem
cells has been amply demonstrated for a number
of cancer types, including
breast cancer (20, 21).
It's the most common
type of non-invasive
breast cancer, meaning the
cells are abnormal but haven't spread to the surrounding tissue.
Both the fruit and its seeds are exceptionally rich in lycopene, a powerful antioxidant that helps protect your
cells from damage caused by free radicals, thus decreasing the risk
of many
types of cancer, including prostate,
breast, ovaries, lung and colon
cancer.
Lauric Acid inhibited the viability
of both
cancer cell types without altering the growth
of MCF - 10A normal
breast epithelial
cells, thus suggesting its specific potential to trigger antiproliferative effects in malignant
cells.
The
breast cancer cells inhibited by the combination were
of a notoriously aggressive
type known as triple - negative.
Scientists were able to link the consumption
of fried meat with the amount
of DNA damage found within women's
breast tissue, the
type of damage that can potentially cause a normal
cell to mutate into a
cancer cell.
While cancerous
cells have a variety
of different causes, excessive alcoholic intake can increase the risk
of various
types of cancers, including neck, liver,
breast, and colorectal, and may play a role in the development
of many other
types of cancers, though the link has yet to be proven.
Researchers from Fox Chase
Cancer Center and the Temple University Health System found that omega - 3 fatty acids from foods such as salmon effectively slowed or stopped cancerous cell growth in triple - negative breast cancer cells more effectively than cells from other types of the di
Cancer Center and the Temple University Health System found that omega - 3 fatty acids from foods such as salmon effectively slowed or stopped cancerous
cell growth in triple - negative
breast cancer cells more effectively than cells from other types of the di
cancer cells more effectively than
cells from other
types of the disease.
Concern about alkylphenols first surfaced decades ago when a group at Tufts observed an excessive proliferation
of human
breast cancer cells in certain
types of plastic containers, something that would normally only be seen if the
cells were exposed to some
type of estrogen.
Melatonin is important for the proper functioning
of your immune system, scavenging free radicals, reducing inflammation, and helping your body to rid itself
of cancer cells; multiple studies point to the role
of melatonin in protecting you from multiple
types of cancer, including
breast cancer
Curcumin inhibits the growth and spread
of different
types of cancer cells, in particular leukemia, hepatic, colorectal, pancreatic, gastric, prostate,
breast, and oral
cancers.
In contrast, a striking increase in
breast cancer incidence has been noted in migrants who abandon traditional diets (e.g., rice, vegetables, and soy foods) and adopt Western —
type diets high in meat, dairy products, and fat.Part
of this risk may be related to eating fiber — depleted, fatty foods that increase blood levels
of estrogen or to an increase in estrogen production from fat
cells.
One study examined the cytotoxic effects
of different
types of clove extract on
breast cancer cell lines, including water - based, alcohol - based and essential oil extracts.