Sentences with phrase «type of cancer therapy»

The third one is that you can get memory and that's the hallmark of the immune system that doesn't exist for any other type of cancer therapy.

As part of a second trial, Swanton's lab will also study what happens to tumors under the selective pressure of various types of cancer therapies, from traditional chemotherapy to targeted drugs.

Not exact matches

The treatment is a type of so - called CAR T - cell therapy — taking a patient's own immune cells, called T cells, genetically manipulating them to attack specific proteins on cancer, and infusing them back into the patient.

Gilead subsidiary Kite Pharma (which the biotech giant scooped up ahead of the FDA's approval for Yescarta, a treatment that reengineers patients» immune cells to fight cancer) will have access to Sangamo's platform technology, which could be used to create various types of cancer cell therapies.

Gilead's therapy (which the biotech giant acquired after snapping up developer Kite Pharma for just under $ 12 billion at the end of the summer) is approved for certain types of the blood cancer non-Hodgkin lymphoma.

Overall, about one - third of men with prostate cancer receive some type of radiation therapy.

Revving up the immune system to combat a wide variety of tumor types may take cancer therapy in a new direction, says Khaled Barakat, a computational scientist at the University of Alberta in Canada, who was not involved in the study.

A type of immune therapy known as PD - 1 blockade controlled cancer in 77 percent of patients with defects in DNA mismatch repair — the system cells use to spell - check and fix errors in DNA (SN Online: 10/7/15).

The type, intensity and duration of immunosuppressive therapy contribute to the risk of developing skin cancer, such as melanoma, after transplantation.

Patients with metastatic non-small cell lung cancer will always progress after chemotherapy, so most patients go on to be treated with immunotherapy, a type of therapy that uses the body's immune system to fight cancer.

Frequent, low - dose chemotherapy regimens avoid this effect and may therefore be more effective at treating certain types of breast and pancreatic cancer, according to the murine study «Metronomic chemotherapy prevents therapy - induced stromal activation and induction of tumor - initiating cells,» which will be published online November 23 in The Journal of Experimental Medicine.

The findings — published today in Nature — provide significant insights into cell types fated to relapse and can help accelerate the quest for new, upfront therapies, says Dr. Dick, a Senior Scientist at Princess Margaret Cancer Centre, University Health Network, and Professor in the Department of Molecular Genetics, University of Toronto.

Over the past 2 decades, few effective treatments for this cancer type have been identified, as PanNETs» heterogeneity has complicated the design of targeted therapies.

This therapy may also be used for other types of cancer.

He also plans a multicenter / multinational study of patients with melanoma or other types of cancer, to examine the effect of long - term CPAP therapy on those also diagnosed with sleep apnea.

«I am so happy that more of these types of nanoparticle - based hyperthermal therapies are being developed to increase the arsenal of weapons against cancer.»

That trend is problematic considering that African - Americans — the most at - risk population for multiple myeloma — have different genetics that can affect how this type of cancer progresses and what kind of targeted therapies are most effective, said Zarko Manojlovic, lead author of the study.

«However, additional research is needed to further evaluate the therapy for this type of ovarian cancer.»

For example, they were more likely to start hormonal therapy, which is considered the gold standard in treatment for certain types of breast cancer.

Cancer stem cells are strongly associated with the growth and recurrence of all cancers and are especially difficult to eradicate with normal treatment, which also leads to tumours developing resistance to other types of therapy.

Therefore, safer therapeutic therapies that are more effective are being sought for this deadly type of cancer in women.»

All had been treated previously with at least one type of androgen deprivation therapy and had rising levels of prostate specific antigen (PSA), a blood marker for prostate cancer, and radiographic evidence their cancers were becoming resistant.

There is an expanding array of nanoparticle types being developed and tested for cancer therapy.

Genetic analysis of cells allows therapies to be adapted to the type of cancer to be treated.

«Multiple epigenetic regulators participate in the drug - desensitizing pathway, so they could serve as new targets to improve therapy for this type of cancer.»

The findings, which were published online in the journal Cancer Cell, could ultimately lead to new targeted therapies for many other types of cancer carrying similar p53 mutaCancer Cell, could ultimately lead to new targeted therapies for many other types of cancer carrying similar p53 mutacancer carrying similar p53 mutations.

The technique, which captures a molecular fingerprint of the disease, can be used to customize therapy to best fight a patient's particular type of cancer.

Genetically modified «hunter» T cells successfully migrated to and penetrated a deadly type of brain tumor known as glioblastoma (GBM) in a clinical trial of the new therapy, but the cells triggered an immunosuppressive tumor microenvironment and faced a complex mutational landscape that will need to be overcome to better treat this aggressive cancer, Penn Medicine researchers report in a new study this week in Science Translational Medicine.

They are examining every aspect of cell function and cell structure, looking for clusters of phenotypes that could label a patient's cancer so precisely that it could be linked to therapies proven effective against just that type.

«We desperately need better, more targeted therapies for both types of bladder cancer.»

Perhaps shedding light on this mystery, the researchers found three different types of mutations in the estrogen receptor in patients whose cancer was resistant to anti-hormone therapy.

«While there is understandable excitement around new therapies that enlist the immune system to fight cancer, we are still in a situation where greater than half of patients don't respond in melanoma and the response rate is even worse in other cancer types,» Hanks said.

DFMO is being investigated in human clinical trials to treat some types of cancer, but it hasn't been tested as a potential therapy for Alzheimer's.

It is commonly thought that bladder cancers that develop after pelvic radiation tend to be aggressive, with high grades and stages, but this study found that the types, grades, and stages of bladder cancer that developed were similar in patients treated with and without radiation therapy.

If these preclinical studies are successful, the researchers plan to further develop their CAR T cell therapy and test its safety and efficacy for different types of metastatic cancer in upcoming clinical trials.

Currently, there are no molecularly targeted therapies aimed at triple - negative breast cancer, which is a type of cancer negative for estrogen receptor, progesterone receptor and the HER2 protein — all key targets for current therapies.

Survivors should be assessed for physical (e.g.: urinary, sexual, bowel) and psychosocial effects of prostate cancer and its treatment; the focus of assessment should be tailored to the type of cancer treatment received and current disease state to trigger appropriate self - management and clinical management strategies for support and therapy.

TNBC is the only type of breast cancer for which there are no currently approved targeted therapies.

«Since doxorubicin is one of the cheapest drugs that is effective against many types of cancer but rarely used in colon cancer, the combination therapy could be highly effective in combating colon cancer while drastically lowering risk of cardiotoxic side effects.»

The goal of this type of therapy is to block the male hormones, including testosterone, from stimulating the growth of the prostate cancer cells.

Surgery is the only potentially curative therapy for individuals with pancreatic ductal adenocarcinoma (PDA), the most common type of pancreatic cancer.

Breast conserving therapy (BCT, breast conserving surgery combined with radiation therapy) is superior to mastectomy in certain types of breast cancer patients, according to results from the largest study to date, to be presented to the European Cancer Congress 2017 today (Mocancer patients, according to results from the largest study to date, to be presented to the European Cancer Congress 2017 today (MoCancer Congress 2017 today (Monday).

So, for example, if one type of immunotherapy is used to knock out an inhibitory signal produced by a cancer, and the tumor responds by upregulating a second signal, an additional therapy could then be used to target this one as well, Lu says.

In efforts to enhance pre-clinical drug testing, Thomas Gaddy of the University of Southern California, Los Angeles, and colleagues in the research group of Professor Stacey Finley investigated a potential predictive biomarker for a type of cancer drug known as anti-angiogenic therapy.

TNBC is deadly because, unlike other types of breast cancers such as estrogen receptor (ER) positive or HER2 amplified breast tumours which have effective targeted therapy, TNBC tumours do not respond to targeted therapy.

In further studies, they plan to explore the role of autophagy in immune reactions toward other tumor cell types, to determine whether such therapies might be effective in a broad range of cancers.

«In its original review of these studies, the UK Gene Therapy Advisory Committee recognised the possibility of cancer occurring as a result of this type of gene therapy,» says Norman Nevin, GTAC's chTherapy Advisory Committee recognised the possibility of cancer occurring as a result of this type of gene therapy,» says Norman Nevin, GTAC's chtherapy,» says Norman Nevin, GTAC's chairman.

«Triple - negative breast cancers tend to be more aggressive compared to other types of breast cancers, and being able to predict response to therapy could greatly impact treatment decisions and patient outcomes,» says study author Shaveta Vinayak, MD, oncologist at UH Case Medical Center and Assistant Professor at Case Western Reserve University School of Medicine.

CRI: What other types of cancer do you think would next be eligible for this type of therapy?

Most of these therapies are still in early - phase testing (phase I and II) for ovarian cancer, but their successful use in other types of cancers suggests that they may ultimately prove useful for ovarian cancer as well.