Sentences with phrase «type of cells seen»

Not exact matches

Most cases of type 1 diabetes occur when the body mistakenly sees the islet cells as a foreign invader and wrecks the thing.

A new type of human stem cell, never seen in nature, should be better at making replacement organs than existing stem cells

«What this research shows is that they're using the same cell types with the same kinds of connections we see in the neocortex, but with a very different kind of organization.»

Mahmoudi and his colleagues previously identified several others overlooked biological factors that appear to contribute to discrepancies seen between results in the lab and in the clinic, including importance of personalized medicine at the nanobio interfaces, cell type, cell shape, and incubating temperature.

In a study published in 2006, he and other Johns Hopkins researchers tested two compounds similar to CGP3466B to see if they would block GAPDH from triggering cell death under the types of highly stressful conditions that would normally cause apoptosis.

Richard Bennett of Brown University in Providence, Rhode Island, and his colleagues mixed the two types and saw matings between same - sex cells, but only a few (Nature, DOI: 10.1038 / nature08252).

This is how treatments based on a type of white blood cell called T - cells are curing some cancers, rather than just slowing their advance (see «Cancer meets its nemesis in reprogrammed blood cells «-RRB-.

One advantage of this method is that it only activates a certain type of immune cell, the dendritic cell or T - cell, and only in one part of the body, near the draining lymph nodes or tumor, which helps cut down on the system - wide side effects often seen with chemotherapy.

The two - part approach netted a set of mutations seen only at relapse that enabled the team to sift and sort leukemic and normal stem cells using tools developed in the Dick lab a few years ago to zero in on specific cell types fated to relapse.

«We want to start looking system by system to see how widely acting this process is on different types of cells,» he says.

[Chinedu Nwokoro et al., «Inhaled black carbon in the lower airways of London cyclists»] Researchers at the London School of Medicine collected sputum samples from healthy non-smokers who walk or bike to see how much black carbon was in airway macrophages — a type of white blood cell that takes in foreign material.

Murphy found that the normal pattern of gene activation seen in aging wild - type C. elegans was reversed in the body cells and oocytes of IGF - 1 mutants.

Researchers say their findings, published in Annals of Neurology, are «surprising» as the results differ from what has been seen in studies of brain regions that harbor other brain cell - types.

Now, with new kinds of technologies that are coming up, new types of tissue engineering and, you know, some of the hopes that people have for stem cells and [the] like, it may be interesting to see if there are other ways, alternatives to dealing with really badly damaged hearts that would involve growing a new heart or replacing or repairing the damage d to a badly damaged heart that might make artificial hearts less important in the somewhat more distant future.

Researchers have found that when properly enticed, some types of specialized human cells can revert to a more nascent state (see p. 85).

«The type of inflammation we see in psoriasis is similar to what we see in atherosclerosis — a type of heart disease that involves the build - up of fats, cholesterol, and inflammatory cells in the artery walls,» Gelfand said.

If the finding that resident memory T cells are the most potent mediators of immunity holds up in different types of cancer, which I think it will, you could take a biopsy of the lung or the pancreas, for example, to see if there are resident T cells there.

The researchers also wanted to revisit the Trojan horse hypothesis, to see if, as had been proposed, infected monocytes, a type of immune cell, might be responsible for carrying the parasite into the brain.

For the first time ever, we could make a really comprehensive comparison of individual normal and tumour cells from the exact same type of tissue, taken at the same time, from the same person, and see how the cancer had developed.»

«If you are an experimental biologist, in your experiments you see an amazing variety of cell types.

These stem cells — known as induced pluripotent stem cells or iPS cells — can be turned into almost any specialised cell type of the human body, including the cells we need to see.

«It's just gorgeous to see this kind of coordinated dance of these two cell types being orchestrated over the course of development,» Dr. Mann said.

«This type of imaging is so important because it allows us to see and measure relationships between cells and their environment,» Cohen said.

The next species we will be looking to study is Saxifraga lolaensis, which has super tiny leaves with an organisation of cell types not seen in a leaf before, and which we think will reveal more fascinating secrets about the complexity of plants.»

«We've seen this in six different types of human cancer cell lines in the lab,» Choudhury said.

They used genetic knockout mice to look for the cells, silencing different types of TRCs, then flushing the rodents» mouths with water to see which cells responded.

Optogenetics works at micro scale, and fMRI covers wide regions of the brain — together this means that scientists have a way to intervene and experiment with entire brain circuits, to finally see how a certain type of brain cell affects the wider global activity of the entire brain.

Basically, when you look at different types of cells, such as fibroblasts, which form connective tissue, or epithelial cells, from saliva, you see general correlations within a person.

The different types of resulting brain cells were then stained in the fluorescent colors seen here.

«Further studies are needed to understand the connections we're uncovering and the roles of these proteins, but we're clearly seeing evidence that these genetic variants have an effect in this type of immune cell.»

In order to figure out how this type of immunotherapy works, the scientists delved inside the immune cells themselves to see which genes and proteins were turned on or off by the treatment.

The researchers then attempted to see if the cells, which they labeled multipotent adult germline stem cells (maGSC), would differentiate into specific types of body cells.

«In normal conditions, we first see the cells as yellow — the combination of red and green within a single cell — then later see cells that are either red or green, showing that our cells had the capacity to make two different types of mature cells,» says Spike.

We decided to look at the exosomes of stromal cells, a type of cell that is commonly found in the tumor microenvironment, and see if stromal exosomes were influencing the energy consumption of cancer cells.»

Using specific, known types of cells allowed the researchers to see where the developing brain is most vulnerable, Song says.

I think what we are seeing with this study is just the tip of the iceberg, where the process of protein production is probably quite different in distinct cell types.»

«If you went back a few years and opened a textbook you'd see the classic hippocampal circuit that's been diagrammed for a hundred years, and you'd look at the subiculum and you'd see it labeled as one region, with one type of cell, doing one thing,» Cembrowski explains.

p85 also is present in insulin - producing pancreatic beta cells, and we will also see if changing the level of p85 in beta cells will make them more resilient when stressed with high insulin demands like those from early type 2 diabetes.»

«We also discovered that this type of regulation is, interestingly, specific to beta cells, and not seen in other metabolic cell types such as liver and fat cells,» he says.

Indeed, in our tissues we found these type of cells are indeed present, and associated with the vasculature as can be seen in the immunohistochemistry for NG2 and PDGF receptor beta.

Researchers at Pacific Northwest National Laboratory and East China Normal University devised and tested a thin - about as thin as the skin of a soap bubble - film composed of a special type of molecules called peptoids that can repair itself, similar to the self - repair seen in cells of living organisms.

Cembrowski also wants to extend this work across the full extent of the subiculum to see if they can identify additional cell types.

Histopathological examination of rejected corneal allografts in CD4 KO mice revealed a mixed inflammatory infiltrate containing large numbers of neutrophils and mononuclear cells, which was indistinguishable from the infiltrate seen in rejected corneal allografts in wild - type mice (data not shown).

By manipulating the signals that the cells see at a particular time, the researchers were able to influence what type of cell they become and how they are organised.

Additionally, it will be important to see whether this role of Chd1 as a regulator of stem cell potency is maintained in human ESCs and other stem cell types.

«We compiled a list of the proteins we thought Zika and similar viruses like dengue were using to get inside of cells, and then we looked to see which of these proteins were abundantly present in the different cell types of the developing brain,» said Pollen, who did the work with Tomasz Nowakowski, PhD, and a UCSF graduate student Carmen Sandoval - Espinosa, BS, both in Kriegstein's lab.

«The second aim of the study was to see whether pancreatic insulin and enzyme secretions are controlled by different types of vagal motoneurons — the cells of the nervous system that control motor functions of the pancreas through the vagus nerve.»

As a result, the mice failed to show the type of progressive nerve cell damage seen in MS.

Nivolumab is an antibody (a type of human protein) that is being tested to see if it will allow the body - s immune system to work against tumor cells.

Clinical trials are now underway that aim to see if the large populations of T regulatory cells generated in the thymus can be exploited to better protect against type 1 diabetes.