One of these escape mechanisms involves
a type of immune cell called myeloid - derived suppressor cells (MDSCs).
Wong studied how the SIRT1 protein controls
a type of immune cell called T helper cells, which have been linked to inflammation and autoimmune disorders, such as multiple sclerosis and arthritis.
Older studies have shown that certain compounds can activate iNKT cells in mice by stimulating the response of
another type of immune cell called cytokines.
Ipilimumab targets a protein called cytotoxic T lymphocytic antigen - 4 (CTLA - 4) that is found on
a type of immune cell called a T cell.
Moffitt researchers wanted to determine if it would be possible to activate the cancer - fighting properties of T cells indirectly by targeting
another type of immune cell called a dendritic cell.
A few years ago, MS researchers were focused on a new
type of immune cell called the Th - 17 cell, which appeared to be a key player in driving the neuronal damage in MS. Because Th - 17 cells produce the cytokine IL - 17, researchers likewise thought this chemical was essential to the disease.
Blood tests showed that IL - 7 curbed the production of SOCS3 in
a type of immune cell called a T - cell, thereby boosting T - cell response.
«A personalised immunotherapy was prepared for each patient by taking a sample of their blood and extracting a particular
type of immune cell called dendritic cells.
Asthma has been correlated with an overabundance of one
type of immune cell called M2 macrophages in the lungs.
The cells are a recently discovered
type of immune cell called Th17.
The scientists zeroed in on
a type of immune cell called regulatory T - cells, which were known to suppress autoimmune responses.
In the early stages of infection, HIV hides in viral reservoirs in
a type of immune cells called T cells.
Not exact matches
The treatment is a
type of so -
called CAR T -
cell therapy — taking a patient's own
immune cells,
called T
cells, genetically manipulating them to attack specific proteins on cancer, and infusing them back into the patient.
Baby Layla's medical team treated her with
immune cells altered by one
type of the molecular surgical instruments
called TALENs.
A second
type of immune system
cell,
called regulatory T
cells (Tregs), are a model
of constancy, remaining stable even as Teffs go into battle mode.
The new findings build on prior research from the Dhodapkar lab demonstrating that patients with Gaucher disease, an inherited lipid storage disorder, have a significant increased risk for developing myeloma; and the discovery
of a subset
of lipid - reactive
immune cells,
called type II NKT - TFH, that promote the development
of plasma
cells.
THC activated two
types of cannabinoid receptor on
immune cells,
called CB1 and CB2.
The researchers studied two
types of cells called effector T
cells, which activate the
immune system to defend our body against different pathogens, and regulatory T
cells, which help control the
immune system and prevent it from attacking healthy parts
of its environment.
Immune messenger molecules
called cytokines and certain
types of immune cells race to the bite site, making it inhospitable for the parasite.
Current thinking regarding
type III hypersensitivity is that
immune cells within tissues sense the presence
of these
immune complexes (ICs) through specific receptor molecules and release inflammatory factors
called cytokines that activate the endothelial
cells lining adjacent blood vessels to promote the recruitment
of neutrophils.
Researchers have identified a group
of immune system genes that may play a role in how long people can live after developing a common
type of brain cancer
called glioblastoma multiforme, a tumor
of the glial
cells in the brain.
In normal
immune responses, a second
type of helper
cells, known as TH2, secrete another batch
of cytokines, including one
called interleukin - 4 (IL - 4) that turns off the cytokine release from TH1
cells.
IL - 17 attracted other
immune cells called neutrophils — the most abundant
type of white blood
cell — to the conjunctiva and induced the release
of anti-microbial proteins into the tears.
Looking for
immune abnormalities throughout the lifespan
of the mice, the group found that most
immune system components stayed the same in number, but a
type of brain - resident
immune cells called microglia that are known first responders to infection begin to divide and change early in the disease.
The researchers modified a
type of human
immune cell —
called T lymphocytes, or T
cells — to target a molecule
called CS1, which is found on more than 95 percent
of myeloma
cells, and to kill the
cells.
Lymph nodes have microscopic compartments
called «follicles,» where they store a specific
type of immune cells, the B -
cells.
This «friendly fire» goes unchecked due to the failing
of another
type of immune cell:
called the T - reg, which controls T - effector
cells, shutting them down when they are not needed.
Some sentries
of the
immune system — so -
called B
cells, which are charged with checking out the passersby
of the bloodstream — undergo a
type of basic training.
Johannes Scheid, a student in Nussenzweig's lab, isolated it several years ago from an HIV - infected patient whose
immune system had an exceptional ability to neutralize HIV in the blood by preventing the virus from infecting and destroying a specific
type of immune cells,
called CD4
cells, in patients.
The bacteria hide within human
cells called macrophages, escaping the body's own
immune defenses and being shielded from many
types of antibiotics.
The current study involved monitoring the patients for one year after completed stem
cell transplantation and used mass cytometry to study the different
cell types of the
immune system and the so
called ProSeek method for simultaneous protein analysis.
«We showed that there are markers on these stomach tumour
cells that indicate they would be responsive to a
type of immunotherapy
called immune checkpoint inhibitors, in particular anti-PDL1 immunotherapy, which is already used with great success in the treatment
of melanoma and certain other cancers.
If it does, then you might use the approach
of making more beta
cells right at early onset
of the
type 1 disease to try and stop or reverse the
immune attack, making the
immune system think its made a mistake, inducing something
called anergy by making more beta
cells.
Normally, two
types of immune cells,
called T
cells and B
cells, protect the body from invading viruses, bacteria and fungi.
11/6/2007 UCSD Researchers Discover Inflammation, Not Obesity, Cause
of Insulin Resistance Findings may have important potential for new drug discoveries in fight against
Type 2 diabetes Researchers at the University
of California, San Diego (UCSD) School
of Medicine have discovered that inflammation provoked by
immune cells called macrop... More...
In their latest work, reported online in the Journal
of Clinical Investigation, the scientists analyzed blood from such mice and identified two
types of autoimmune response directed specifically against the protein, with the first response directed by a specialized kind
of immune system
cells called T
cells and the second by antibodies.
For decades, scientists have been seeking a new
type of vaccine that activates another player in the
immune system
called a T
cell to fight off infections within different organs.
In Sabrina's poster, she showed that patients with a low number
of different
types of T -
cells (a
type of immune cell which has different versions to fight different infections / diseases;
called a T -
cell repertoire or TCR) in their blood at start
of treatment were more likey to respond to anti-PD1 therapy, and had a poor response to anti-CTLA4 therapy.
Kidney cancer — also
called renal
cell cancer — is one
of the major
types of cancer for which new
immune - based cancer treatments are currently in development.
The study specifically targets two different
types of brain
cells,
called microglia and astrocytes, that work to keep the
immune system in check and clear out old and damaged
cells, preventing disease.
The common identifying factor in most autoimmune diseases is a destructive processes
called inflammation which will eventually cause the destruction
of cells and tissues specific to the
type of auto -
immune disease he person has.
Moreover, the idea that the brain was isolated from
immune reactions was challenged long ago by insights about microglia
cells, a
type of macrophage which resides in the brain, engulfs antigens, and produces pro-inflammatory signaling molecules
called cytokines.
A study published in Nature suggests that a
type of white blood
cell called Th17 play a critical role in autoimmunity (
immune attack on healthy
cells).
It replicates in a particular
type of cell called a T - lymphocyte, which is responsible for regulating the
immune system.
The histiocytoma is a tumor originating from what is
called a Langerhans
cell, a
type of cell that resides in the skin as a part
of the
immune system.