We're leading and participating in clinical trials to find out how well immunotherapy can shrink kidney cancer tumors when it's given in combination with systemic drugs like targeted therapies or on its own by combining
different types of immunotherapy drugs.
In an article published in the January issue of Cancer Cell, the researchers describe how a new
type of immunotherapy drug targeting the protein TIM - 3 works to stimulate the immune system.
For metastatic melanoma, there are currently three different
types of immunotherapy approved for use, and we specifically looked at that population of people.»
SLIT may be preferred to injections because of the ease of administration; however, when choosing
which type of immunotherapy to try, clients need to understand that oral immunotherapy is given twice daily every day and requires a greater time commitment than subcutaneous injections.
In addition to bevacizumab (Avastin ®) a targeted antibody that is already approved for cervical cancer patients, there are several
other types of immunotherapies that are being evaluated for cervical cancer, including some in combination.
In this special digital package, we have pulled together other recent Scientific American articles about different
types of immunotherapy that tell you even more about this exciting next generation of cancer treatment.
Commenting on the research, Prof Rolf Stahel, Professor of oncology at the University Hospital Zurich in Zurich, Switzerland, said: «The findings suggest that the addition of
this type of immunotherapy improves the response rate, and provides a longer progression free survival, compared to what would be expected with chemotherapy alone.
With these checkpoint blockade drugs [
this type of immunotherapy] there is a pretty high quality of life and patients can quickly return to the workplace.
The studies, which appear online in Science, track responses to
a type of immunotherapy known as a PD - 1 inhibitor.
Currently, investigators around the world are experimenting with restoring the immune cells responsible for keeping CMV in check by transplanting those specific anti-viral cells from healthy donors —
a type of immunotherapy.
In order to figure out how
this type of immunotherapy works, the scientists delved inside the immune cells themselves to see which genes and proteins were turned on or off by the treatment.
So, for example, if one
type of immunotherapy is used to knock out an inhibitory signal produced by a cancer, and the tumor responds by upregulating a second signal, an additional therapy could then be used to target this one as well, Lu says.
The results also should spur future studies of combined regimens of CDK4 / 6 inhibitors and different
types of immunotherapy, the authors state.
City of Hope researchers have found that using CAR T therapy,
a type of immunotherapy, can be effective in the treatment of glioblastoma — one of the most aggressive brain tumors known to medicine.
«If we can find the mechanism by which tau spreads from one cell to another, we could potentially stop it from jumping across the synapses — perhaps using
some type of immunotherapy.
«We showed that there are markers on these stomach tumour cells that indicate they would be responsive to
a type of immunotherapy called immune checkpoint inhibitors, in particular anti-PDL1 immunotherapy, which is already used with great success in the treatment of melanoma and certain other cancers.
In 2015,
another type of immunotherapy — oncolytic virus therapy — was approved for the local treatment of unresectable cutaneous, subcutaneous, and nodal lesions in patients with melanoma that has recurred after initial surgery.
Adoptive cell therapy is
a type of immunotherapy in which immune cells are removed from a patient, grown or genetically modified in lab, and then given back to the patient, often in vastly increased numbers.
CTLA - 4 inhibitors belong to the family of «immune checkpoint inhibitors» —
a type of immunotherapy that helps in controlling the body's immune response to cancer.
PD - 1 / PD - L1 inhibitors belong to the family of «immune checkpoint inhibitors» —
a type of immunotherapy that helps in controlling the body's immune response to cancer.
Details of a first - in - human case report showed that a patient with melanoma was able to achieve a durable complete response with the combination of two
types of immunotherapy.