Sentences with phrase «type of tumor found»

Mammary tumors in dogs are among the most common type of tumor found in intact female dogs.

Mammary tumors in dogs are among the most common type of tumor found in intact (unspayed) female dogs (found in 1 in 4 dogs).

SCC is the most common eye - related cancer in horses and the second most common type of tumor found in horses overall.

Not exact matches

The study found an increased risk of cardiac schwannoma, a tumor type that typically originates from cells found in neurons.

But there can be several different types of cell in a uterine carcinosarcoma tumor, including ones that are not usually found in the uterus.

They found that depending on the cell of origin, mutations in PIK3CA and p53 induced very different types of tumors.

In the Cell study, Dr. Massagué, with Fellow Manuel Valiente, PhD, and other team members, found that in mouse models of breast and lung cancer — two tumor types that often spread to the brain — many cancer cells that enter the brain are killed by astrocytes.

With that knowledge, they screened more than four dozen monoclonal antibodies — unique agents that can stop cells from growing or forming tumors and can be mass produced — before finding two that block tumor creation in both types of cancer.

The findings also have potential uses for most other types of solid tumors, including those affecting the lungs and ovaries, because the same protein and enzyme are involved, François said.

Most cancer vaccines developed to date have been designed to recognize and attack a specific known molecule — such as a cell - surface receptor — that is likely to be found on cancerous cells in any patient with that type of tumor.

PTEN prevents tumor cells from growing uncontrollably, and mutations in the gene encoding this protein are commonly found in many different types of cancer.

In earlier studies involving animal models and human cancer cell lines, researchers found that breast cancer spreads when three specific cells are in direct contact: an endothelial cell (a type of cell that lines the blood vessels), a perivascular macrophage (a type of immune cell found near blood vessels), and a tumor cell that produces high levels of Mena, a protein that enhances a cancer cell's ability to spread.

If such an indel is found in this gene, Ding and her colleagues suggest a patient may benefit from an EFGR inhibitor, such as erlotinib, regardless of the tumor type.

Through their analysis, the researchers determined the genetic alterations found in both the primary tumors and the metastases frequently were a type of genetic abnormality called a copy number alteration, which is when sections of DNA are repeated (i.e. duplicated).

Cancer stem cells, a type of self - renewing cell found in tumors, are of particular interest because they are the main cell type responsible for tumor progression and for resistance to chemotherapy and radiotherapy, and therefore a major cause of tumor recurrence after treatment.

«Not only did we find that LIGHT expression promoted tumor regression, upon further study we also identified the specific type of T - cell — CD8 — that was responsible for shrinking the tumor,» Maker said.

The mean age of the K: B fusion population was 7.4 years old, compared to 15.2 years old in the non-K: B population; 73 percent of the K: B PAs were found in the cerebellum, whereas 78 percent of the non-K: B PAs were found elsewhere; and non-K: B PAs were much more likely associated with co-occurrence of the disease Type 1 Neurofibromatosis, which can lead to the formation of additional tumors.

Researchers found that patients with a higher amount or higher proportion of an inflammatory protein called type 1 interferon beta compared with another inflammatory protein, type 1 interferon alpha, do not respond as well to tumor necrosis factor inhibitors as others.

«Enzyme could protect against type of colorectal cancer by suppressing tumors, study finds.»

Ben - Gurion University of the Negev (BGU) researchers have found that babies born from mothers who underwent fertility treatments are at increased risk of developing many types of pediatric cancers and tumors (neoplasms).

Surprisingly, they found that although the patterns of gene expression — as shown by the RNA sequencing — differed between the hepatocellular carcinomas and the liver cancers with biliary phenotype and depended on the histological type, the overall pattern of mutations in the cells was actually similar between the tumors — of either type — that had emerged in patients who had had infections with either hepatitis C or B, and were different in patients without such infections.

An enzyme that plays an active role in inflammation could be a natural way to suppress tumors and ulcers in the colon that are found in colitis associated cancer (CAC), a type of colorectal cancer that is driven by chronic inflammation, according to a new study.

«This aspect of the research is one of the most intriguing findings to come out of the TCGA program, which has been looking at more than 30 tumor types over the past decade.»

«Our findings suggest a simple strategy to kill metastatic melanoma — regardless of cell type within the tumor — by combining anticancer drugs with diabetes drug,» Herlyn said.

In a report on one of the two findings, published online Sept. 20 in Acta Neuropathologica, the investigators identified alterations in a protein known as ATRX in human brain tumors that arise as part of a genetically inherited condition known as neurofibromatosis type 1 (NF1).

«We were amazed when we found this new type of disease — tapeworms growing inside a person, essentially getting cancer, that spreads to the person, causing tumors,» said study researcher Dr. Atis Muehlenbachs, a staff pathologist at the Centers for Disease Control and Prevention's Infectious Diseases Pathology Branch (IDPB).

«And we found all three types of «gain - of - function» mutations in the estrogen receptor gene ESR1 in the tumor samples.»

It is known that the genes that accumulate the most mutations are linked to the tumor type, and we found this too, however we showed that the mutational spectrum of a tumor is determined by breed type,» says Dr. Ingegerd Elvers, a researcher with Professor Kerstin Lindblad - Toh at both Uppsala University and Broad Institute.

Researchers from Uppsala University, Sweden, and the Broad Institute, USA, have identified both similarities and differences between a single tumor type in multiple dogs breeds; a finding they believe parallels the situation in the cancer of human patients.

IL - 6 is a cytokine, a signal molecule that is produced and secreted both by immune cells and by tumor cells and binds specifically to a receptor (IL - 6R) that is found on the surfaces of many cell types.

Overall, including all genomic variations present in most if not all tumor cells (clonal) as well as those present only in subsets of the cancer cells (subclonal) from tumor tissue, the researchers detected a total of 864 genetic changes in tissue samples across the three tumor types, and 627 (73 %) of those were also found in the blood.

In people under age 30, radiation is a risk factor for a type of brain tumor called a meningioma, a Loyola University Medical Center study has found.

They found that carcinoma cells from smokers carried the «transcriptional fingerprint» (i.e. the pattern of genes that were switched on or off) of basal cells, suggesting that the tumors may originate from this type of cell.

«The apparent ability to change immunosuppressive T cells within the tumor into T cell types that are more active and potentially helpful against cancer was a really exciting finding, and one that we're continuing to investigate,» says Poznansky, who is an associate professor of Medicine at Harvard Medical School (HMS).

The researchers found what they refer to as the mastermind fusion gene — the first fusion gene associated with this type of tumor.

They found that, in these particular types of tumors, PLK4 regulates tumor growth and the tumor's tendency to metastasize.

These findings show that MAX acts as a tumor suppressor gene in one of the more aggressive types of lung cancer.

The important next step for the field, Cibelli says, is to find reliable ways to differentiate the cells into a variety of useful cell types and to be sure that no undifferentiated cells remain to cause potential tumors.

When they compared the two types of tumor — the localized ones lacking only the PTEN gene versus the metastatic tumors lacking both genes — the researchers found that the metastatic tumors produced huge amounts of lipids, or fats.

We decided to look at the exosomes of stromal cells, a type of cell that is commonly found in the tumor microenvironment, and see if stromal exosomes were influencing the energy consumption of cancer cells.»

To verify these results, the researchers also used mice with APC deleted by traditional methods, and found the same types of tumors.

Cancer researchers have found that certain types of dental X-rays significantly increased the incidence of the most common type of brain tumor in the United States: meningioma.

This method also offers new ways to seek personalized treatments for cancer patients depending on the types of mutations found in their tumors, the researchers say.

«Finding genomic similarities among types of breast, ovarian, endometrial and colorectal tumors once again reveals that cancer, although very complex, may have themes extending beyond tissue type that can be exploited for therapeutic benefit,» said Eric D. Green, M.D., Ph.D., NHGRI director.

A germinoma is a type of germ cell tumor that is most commonly found in the brain.

Researchers also found two types of bacteria in the mouth that may reduce risk of developing esophageal tumor.

These findings suggest that activation of mTOR signaling contributes to tumor cell survival in ALK + ALCL, thus providing a potential therapeutic target in this lymphoma type.

Examples include medulloblastoma and glioblastoma, types of brain tumor, retinoblastoma, a tumor in the retina of the eye, osteoblastoma, a type of bone tumor, and neuroblastoma, a tumor of the nervous system found in children.

A team of investigators led by researchers at Georgetown Lombardi Comprehensive Cancer Center has found that the tumor mutation load (TML) in a patient's cancer biopsy varied by age and the type of cancer.

Tumor - infiltrating lymphocytes, or TILs, are a type of white blood cell found in tumors.