Sentences with phrase «types of alterations»

Depending on the type of alteration you are planning to do, you may require Planning Permission.

Not exact matches

I've noticed in my experience of being a home - based dcp and in centers that babies and young toddlers with this type of scheduling are better able to adapt to change, different care - givers and alterations in general routine.

Half of the patients treated in this study responded to either ponatinib (typically used for certain types of leukemia) or pazopinib (a kidney cancer drug), depending on the genetic alterations identified through sequencing.

Inindividuals with albinism, genetic alterations interfere with the melanocytes» production of pigment or their ability to distribute it to keratinocytes, the major cell type of the skin's outer layer.

«Studies are underway to reveal how seizures affect various types of memory and to explore the associated molecular signaling and morphological alterations,» says author Angela Carter, a predoctoral fellow in the laboratory of Dr. Anne Anderson at the Baylor College of Medicine.

This is because of the obvious concerns about the heritability of the genetic alterations induced, and the way in which such research could spread from work on «non-viable» embryos, to work on viable ones once this type of research had been accepted in principle by international regulatory bodies.»

Through their analysis, the researchers determined the genetic alterations found in both the primary tumors and the metastases frequently were a type of genetic abnormality called a copy number alteration, which is when sections of DNA are repeated (i.e. duplicated).

«Some of these genes were either increased or decreased in the area of the tumour, no matter the type of breast cancer, and this is important because within the patterns we identified were predictable alterations.

In a report on one of the two findings, published online Sept. 20 in Acta Neuropathologica, the investigators identified alterations in a protein known as ATRX in human brain tumors that arise as part of a genetically inherited condition known as neurofibromatosis type 1 (NF1).

Their dual - use aspects «didn't hit the radar screen» of the scientists who reviewed the proposals for NIAID, Fauci says, in part because «similar types of research looking at alteration of transmissibility have been going on forever.»

Methylation is one type of so - called epigenetic changes, alterations in genes during the lifetime that affect their expression.

He suggests that combining genomewide and epigenomewide association studies can overcome problems of assigning cause and effect to specific alterations among either type of study alone.

They also found that the disruption of the connectivity of these cells during brain development causes alterations in brain oscillatory activity and disturbs the function of place cells, a type of pyramidal neuron that becomes active when an animal is located in a particular place in its environment.

This type of variation can cause significant alterations to the genome and lead to psychiatric disorders, said Sebat, who is a professor and chief of the Beyster Center for Genomics of Neuropsychiatric Diseases at UC San Diego School of Medicine.

Alteration of T - type channel expression has been causally linked to a number of pathological conditions including neuropathic pain and absence seizure activity.

The first mechanism involves chemical alteration driven by the types of minerals present and by the diverse and abundant microbial community, which both stabilizes and releases carbon.

Although a large number of genetic alterations that drive the development and progression of many types of cancer have been identified through large - scale research studies, some tumor types have not been deeply characterized.

Wasp genotype influences both Wolbachia density in host tissues [69] and the type and level of reproductive alterations induced by Wolbachia [70]--[72], implying a role of variation in host response in the biology of Wolbachia in Nasonia.

This trend of superior sensitivity for SMG alterations holds across all tumor types:

Please head over to our sister blog eScienceCommons to learn about how two types of white - throated sparrow have differences in behavior, which are driven by a chromosomal alteration.

Recent studies indicated that autoimmune diseases like Type 1 Diabetes (T1D) are induced by genetic or environment - induced alterations of immune regulatory pathways whose function is to avoid or limit the activation / expansion of self - reactive T lymphocytes.

«They concluded that genetic differences and type of fat in the roundworm diet appears to be associated with longevity, and that the reason roundworms lived longer with MUFA might relate to less oxidative stress, or alteration in signalling pathways at cell level that improved their longevity.

SEngine in - depth analysis of the MYC oncogene across 11,000 samples and 33 tumor types published in Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas.

For example, studies of cell signaling pathways in normal cells and cancer cells have contributed greatly to our knowledge about the disease, revealing molecular alterations that are shared among different types of cancer and pointing to possible strategies for treatment.

Unlike most types of gene therapy, a longstanding approach that aims to alter only adult human tissues that die with the patient, the Crispr technique could be used to change human eggs, sperm and early embryos, and such alterations would be inherited by the patient's children.

Sometimes simple alteration in types of fiber can be the easiest solution.

Following CNS damage, microglia change from a surveillant to a reactive state, displaying alterations in cell morphology and phenotypes that vary based upon the type and extent of (insulting) stimulus to which they are exposed and respond.

Studies suggest that gut microbiota alterations due to unhealthy lifestyle and inadequate nutrition may contribute to the pathogenesis of a broad spectrum of diseases such as obesity, diabetes mellitus, non-alcoholic fatty liver disease, colorectal cancer, cardiovascular disease, Parkinson's disease, Alzheimer's disease, and type 2 diabetes.

Most of these alterations are the type of thing that only series diehards are liable to notice, although having the most current and balanced version of Guilty Gear is a good thing for everyone.

For those select few alterations, the Type R Black Edition, which is only available overseas, will cost the equivalent of $ 39,290.

The most common types of non-permitted addition or alteration are garage conversions and utility rooms.

Raising your deductible, lowering your limits, or excluding certain types of perils from your coverage will immediately reduce your rates, but beware: Policy alterations can end up costing you more out - of - pocket if and when an incident occurs where you need your insurance policy to kick in.

Even with the alterations, the in - game armor (and body types) maintains a very male - gazey «bikini armor» approach that is increasingly out of touch.

In this new work, «Ways to Scale», Cooper explores a type of genetic alteration which happens amongst cephalopods — squid, octopi, cuttlefish and nautiluses where they have the ability to alter the genetic makeup of their cells, fine - tuning the information encoded by their genes without altering the genes themselves.

This results in an alteration of the types of vegetation across the tundra.

For other types of work, such as internal alterations, Building Control approval will probably be needed but planning may not be.

Raising your deductible, lowering your limits, or excluding certain types of perils from your coverage will immediately reduce your rates, but beware: Policy alterations can end up costing you more out - of - pocket if and when an incident occurs where you need your insurance policy to kick in.

A type of life insurance policy wherein a policy holder has the facility to make alterations to his / her insurance policy, its premium, and even its term.

«The actual symptoms in terms of intrusions, avoidance, arousal problems, and negative alterations to mood or thinking are very similar across people suffering from PTSD and people suffering from vicarious trauma - type symptoms,» she says.

Recently, researchers have shown an increased interest in paternal psychological status because it is strictly related to maternal one and to child development.9 These few studies evidence that also fathers can be affected by this type of mood alterations and that the transition to parenthood represents a stressor and an anxiety experience for 10 % of fathers, 10 revaluating the paternal role in family functioning after childbirth.9 - 11

That is, the placental enzyme 11β - hydroxysteroid dehydrogenase type 2 (11β - HSD2), which serves as a partial barrier, may be downregulated by an increase in maternal cortisol such that a proportion of maternal cortisol passes through the placenta [50], resulting in alterations in receptor expression in areas accompanying changes in neural development [51].

What types of security procedures are in place to protect the loss, misuse or alteration of information under SelectBlinds.com control.