Sentences with phrase «types of breast cancer cells»

Not exact matches

This type of cancer begins when abnormal cells in the breast ducts divide and multiply quickly.

Molecular characterization of the cells that undergo cell fate transition upon oncogenic Pik3ca expression demonstrated a profound oncogene - induced reprogramming of these newly formed cells and identified gene expression signatures, characteristic of the different cell fate switches, which was predictive of the cancer cell of origin, tumour type and clinical outcomes in women with breast cancers.

In the Cell study, Dr. Massagué, with Fellow Manuel Valiente, PhD, and other team members, found that in mouse models of breast and lung cancer — two tumor types that often spread to the brain — many cancer cells that enter the brain are killed by astrocytes.

The researchers studied triple - negative breast cancer cells, which grow and spread faster than most other types of cancer cells.

In their latest study, they tested compounds against cells from nine different types of human cancer, including common types affecting blood, colon, breast, prostate, ovaries, kidneys, and lungs.

Frequent, low - dose chemotherapy regimens avoid this effect and may therefore be more effective at treating certain types of breast and pancreatic cancer, according to the murine study «Metronomic chemotherapy prevents therapy - induced stromal activation and induction of tumor - initiating cells,» which will be published online November 23 in The Journal of Experimental Medicine.

The data that the breast cancer cells spread more successfully in clumps are compelling, D'Souza - Schorey said, but no one yet knows whether cells from other types of cancer also need help to migrate.

The study published in Cancer Cell shows that exosomes from tumor cells of breast cancer (and other tumor types such as ovarian and endometrial) are different in size and composition than those of healthy Cancer Cell shows that exosomes from tumor cells of breast cancer (and other tumor types such as ovarian and endometrial) are different in size and composition than those of healthy cancer (and other tumor types such as ovarian and endometrial) are different in size and composition than those of healthy cells.

A COMPOUND that slows the proliferation of triple - negative breast cancer cells in lab tests could lead to the first drugs to target this aggressive type of tumour.

Beyond lung cancer, TiY is able to target TICs in 28 types of human cell lines derived from the central nervous system, melanoma, breast, renal, ovarian, colon, and prostate cancer.

In earlier studies involving animal models and human cancer cell lines, researchers found that breast cancer spreads when three specific cells are in direct contact: an endothelial cell (a type of cell that lines the blood vessels), a perivascular macrophage (a type of immune cell found near blood vessels), and a tumor cell that produces high levels of Mena, a protein that enhances a cancer cell's ability to spread.

In animal and cell culture studies, the drug inhibited growth both in estrogen - dependent breast cancer cells and in cells that had developed resistance to the anti-estrogen tamoxifen and / or to the aromatase inhibitors, two of the most widely used types of drugs to prevent and treat estrogen - dependent breast cancer.

«Women with this type of breast cancer also frequently develop metastatic lesions that originate from drug - resistant cells.

Navin's team developed Nuc - Sec as a single - cell genome sequencing method and applied it to study how cell mutations occur in both types of breast cancer.

His research on attaching selenium to the leading clinical chemotherapeutic monoclonal antibody for a type of breast cancer shows it can more effectively kill the cancer cells, he reports.

Neil Johnson's lab at the Fox Chase Cancer Center examined treatment resistance in breast cancer cells expressing the same BRCA1185delAG mutation and determined that the RING - deficient BRCA1 protein was also responsible for loss of sensitivity to certain types of cancer treatCancer Center examined treatment resistance in breast cancer cells expressing the same BRCA1185delAG mutation and determined that the RING - deficient BRCA1 protein was also responsible for loss of sensitivity to certain types of cancer treatcancer cells expressing the same BRCA1185delAG mutation and determined that the RING - deficient BRCA1 protein was also responsible for loss of sensitivity to certain types of cancer treatcancer treatments.

Previous in vitro studies conducted by researchers in other countries showed that this molecule was able to reduce the multiplication and increase the mortality of cells from melanoma, the most aggressive type of skin cancer, as well as breast cancer and neuroblastoma, a tumor that typically affects patients aged 15 or younger.

The 5E5 antibody recognized multiple types of cancer cells, including leukemia, ovarian, breast, and pancreatic cancer cells, but not normal tissues.

The screening revealed coibamide A to be capable of killing many types of cancer cells, but Ishmael decided to focus subsequent studies on two types in particular — brain tumors, or glioblastomas, and a breast cancer subtype known as triple negative breast cancer.

A new study shows coibamide A has potent anti-cancer activity in mice and cell cultures that model brain tumors and triple negative breast cancer, two of the most aggressive and difficult - to - treat types of cancer.

Different types of tumors show a preference for specific organs and tissues; circulating breast cancer cells, for example, are likely to take root in bones, lungs, and the brain.

Dr. David Gilley's laboratory at the Indiana University School of Medicine in Indianapolis and Dr. Connie Eaves» laboratory at the BC Cancer Agency's Terry Fox Laboratory in Vancouver, Canada, collaborated to determine how telomeres are regulated in different types of normal breast cells.

The team found evidence of the process in several other cell types, including breast, ovarian, umbilical cord, and kidney cancer cells.

A research team, led by Chao Cheng, Ph.D., Assistant Professor in the Department of Genetics at The Geisel School of Medicine at Dartmouth, used gene expression data from breast cancer patients to computationally infer the presence of different types of immune cells.

Depending on characteristics such as how many tumor cells, blood vessel cells, and immune cells are touching each other, the tumor microenvironment can nearly triple the chance that a common type of breast cancer (estrogen - receptor positive / HER2 negative) that has reached the lymph nodes will also metastasize, Condeelis and colleagues showed in a 2014 study of 3,760 patients.

Expression of Snail represses expression of E-cadherin and induces EMT in different cell types, including breast cancer cells [36, 37].

-- discovery awarded international science prize Researcher Allison Cleary has, for the first time, demonstrated that different types of tumor cells cooperate in the development and growth of breast cancer.

Researcher Allison Cleary has, for the first time, demonstrated that different types of tumor cells cooperate in the development and growth of breast cancer.

Invasive lobular carcinoma, or ILC, is an uncommon type of breast cancer that begins in the milk - producing lobule cells and invades (spreads) deeper into the breast tissue.

Ductal carcinoma in situ, or DCIS, is a type of breast cancer that begins in the duct cells.

The existence of cancer stem cells has been amply demonstrated for a number of cancer types, including breast cancer (20, 21).

It's the most common type of non-invasive breast cancer, meaning the cells are abnormal but haven't spread to the surrounding tissue.

Both the fruit and its seeds are exceptionally rich in lycopene, a powerful antioxidant that helps protect your cells from damage caused by free radicals, thus decreasing the risk of many types of cancer, including prostate, breast, ovaries, lung and colon cancer.

Lauric Acid inhibited the viability of both cancer cell types without altering the growth of MCF - 10A normal breast epithelial cells, thus suggesting its specific potential to trigger antiproliferative effects in malignant cells.

The breast cancer cells inhibited by the combination were of a notoriously aggressive type known as triple - negative.

Scientists were able to link the consumption of fried meat with the amount of DNA damage found within women's breast tissue, the type of damage that can potentially cause a normal cell to mutate into a cancer cell.

While cancerous cells have a variety of different causes, excessive alcoholic intake can increase the risk of various types of cancers, including neck, liver, breast, and colorectal, and may play a role in the development of many other types of cancers, though the link has yet to be proven.

Researchers from Fox Chase Cancer Center and the Temple University Health System found that omega - 3 fatty acids from foods such as salmon effectively slowed or stopped cancerous cell growth in triple - negative breast cancer cells more effectively than cells from other types of the diCancer Center and the Temple University Health System found that omega - 3 fatty acids from foods such as salmon effectively slowed or stopped cancerous cell growth in triple - negative breast cancer cells more effectively than cells from other types of the dicancer cells more effectively than cells from other types of the disease.

Concern about alkylphenols first surfaced decades ago when a group at Tufts observed an excessive proliferation of human breast cancer cells in certain types of plastic containers, something that would normally only be seen if the cells were exposed to some type of estrogen.

Melatonin is important for the proper functioning of your immune system, scavenging free radicals, reducing inflammation, and helping your body to rid itself of cancer cells; multiple studies point to the role of melatonin in protecting you from multiple types of cancer, including breast cancer

Curcumin inhibits the growth and spread of different types of cancer cells, in particular leukemia, hepatic, colorectal, pancreatic, gastric, prostate, breast, and oral cancers.

In contrast, a striking increase in breast cancer incidence has been noted in migrants who abandon traditional diets (e.g., rice, vegetables, and soy foods) and adopt Western — type diets high in meat, dairy products, and fat.Part of this risk may be related to eating fiber — depleted, fatty foods that increase blood levels of estrogen or to an increase in estrogen production from fat cells.

One study examined the cytotoxic effects of different types of clove extract on breast cancer cell lines, including water - based, alcohol - based and essential oil extracts.