Sentences with phrase «types of cancer cell therapies»

Gilead subsidiary Kite Pharma (which the biotech giant scooped up ahead of the FDA's approval for Yescarta, a treatment that reengineers patients» immune cells to fight cancer) will have access to Sangamo's platform technology, which could be used to create various types of cancer cell therapies.

Not exact matches

The treatment is a type of so - called CAR T - cell therapy — taking a patient's own immune cells, called T cells, genetically manipulating them to attack specific proteins on cancer, and infusing them back into the patient.

A type of immune therapy known as PD - 1 blockade controlled cancer in 77 percent of patients with defects in DNA mismatch repair — the system cells use to spell - check and fix errors in DNA (SN Online: 10/7/15).

Patients with metastatic non-small cell lung cancer will always progress after chemotherapy, so most patients go on to be treated with immunotherapy, a type of therapy that uses the body's immune system to fight cancer.

Frequent, low - dose chemotherapy regimens avoid this effect and may therefore be more effective at treating certain types of breast and pancreatic cancer, according to the murine study «Metronomic chemotherapy prevents therapy - induced stromal activation and induction of tumor - initiating cells,» which will be published online November 23 in The Journal of Experimental Medicine.

The findings — published today in Nature — provide significant insights into cell types fated to relapse and can help accelerate the quest for new, upfront therapies, says Dr. Dick, a Senior Scientist at Princess Margaret Cancer Centre, University Health Network, and Professor in the Department of Molecular Genetics, University of Toronto.

Cancer stem cells are strongly associated with the growth and recurrence of all cancers and are especially difficult to eradicate with normal treatment, which also leads to tumours developing resistance to other types of therapy.

Genetic analysis of cells allows therapies to be adapted to the type of cancer to be treated.

The findings, which were published online in the journal Cancer Cell, could ultimately lead to new targeted therapies for many other types of cancer carrying similar p53 mutaCancer Cell, could ultimately lead to new targeted therapies for many other types of cancer carrying similar p53 mutacancer carrying similar p53 mutations.

Genetically modified «hunter» T cells successfully migrated to and penetrated a deadly type of brain tumor known as glioblastoma (GBM) in a clinical trial of the new therapy, but the cells triggered an immunosuppressive tumor microenvironment and faced a complex mutational landscape that will need to be overcome to better treat this aggressive cancer, Penn Medicine researchers report in a new study this week in Science Translational Medicine.

They are examining every aspect of cell function and cell structure, looking for clusters of phenotypes that could label a patient's cancer so precisely that it could be linked to therapies proven effective against just that type.

If these preclinical studies are successful, the researchers plan to further develop their CAR T cell therapy and test its safety and efficacy for different types of metastatic cancer in upcoming clinical trials.

The goal of this type of therapy is to block the male hormones, including testosterone, from stimulating the growth of the prostate cancer cells.

In further studies, they plan to explore the role of autophagy in immune reactions toward other tumor cell types, to determine whether such therapies might be effective in a broad range of cancers.

Immunotherapy tries to reset our immune response to recognise these hijacker cancer cells but these types of untargeted therapies have many side effects.

T - cell therapy involves genetically re-engineering a type of the patient's own disease - fighting white blood cells, called T - cells, to fight cancer.

He continues to investigate and optimize CAR T cell therapy, to make it more effective not only for blood cancers, but also to help patients with other types of cancer.

Learning what type of cell starts a particular cancer — the «cell of origin» — is extremely valuable, providing insights into tailored therapies that are most likely to work.

Histone deacetylase (HDAC) inhibitor therapy is a type of targeted therapy that blocks enzymes needed for cell division and may stop the growth of cancer cells.

Researchers have found that treating patients who have early stage non-small cell lung cancer with a type of radiotherapy called stereotactic body radiation therapy is associated with a small but increased risk of death from causes other than cancer.

Due to its cell killing effect, radiation therapy is widely used as a primary source of treatment for numerous types of cancers.

If «cancer stem cells» play the critical roles some scientists think they do, anticancer therapy must target more than one type of cell.

Radiation therapy (also referred to as radiation oncology) is a type of cancer treatment that involves the use of the use of high - energy radiation, primarily X-rays, to kill cancer cells and shrink tumors.

In 2016, Dmitry I. Gabrilovich, M.D., Ph.D., program leader of Wistar's Translational Tumor Immunology program, and his research team identified a marker for myeloid - derived suppressor cells (MDSCs), a population of immune cells implicated in tumor resistance to various types of cancer treatment, including targeted therapies, chemotherapy and immunotherapy.

Cancer is an extremely complex biological phenomenon showing enormous variability (e.g., age of patient, cell of origin, general health status, genetic background, location in an organ, nutritional status, presence or absence of continued development of neoplasia (i.e., carcinogenesis), presence or absence of enhancers, rate of growth and division, type and dosage of therapy administered, etc.).

As an aside, many types of cancer cells do NOT have this adaptability and require glucose to thrive, which makes the ketogenic diet an effective therapy for combating cancer.

This type of therapy is designed to kill malignant cancer cells in a defined physical area by exposing them to high levels of deadly radiation.

Mixed or multimodal therapy (use of several types of treatment in combination or using cocktails of anti-cancer drugs) sometimes offers the possibility of maximizing cancer cell killing.

The mission of ACGT is to support the extraordinary potential offered by cell and gene - based therapies to accelerate effective and safe treatment of all types of cancer.