Using tumor samples from a patient, they do lab tests to determine which substances can first make the
different types of cancer cells uniform and then effectively kill them.
Cruciferous vegetables may be antiproliferative, and produce anti-tumor activity which may inhibit
several types of cancer cell growth including leukemia, prostate, breast, cervical, and lung cancer.
As the search for non-toxic natural treatments continues, lycopene — a nutrient found in tomatoes — is impressing researchers with its ability to inhibit
various types of cancer cell growth.
Researchers in the UNC School of Medicine found that the protein DAZAP1 plays a key role in the regulation of many genes through a process known as alternative splicing, and when highly expressed in cancer cell line experiments, DAZAP1 was shown to inhibit several
types of cancer cells from dividing and moving.
It can also kill many different
types of cancer cells by triggering apoptosis (programmed cell death) without affecting normal cells.
Gilead subsidiary Kite Pharma (which the biotech giant scooped up ahead of the FDA's approval for Yescarta, a treatment that reengineers patients» immune cells to fight cancer) will have access to Sangamo's platform technology, which could be used to create various
types of cancer cell therapies.
«Different
types of cancer cells with different strengths and weaknesses are both present in the tumor at the same time and can work together to spread faster and more efficiently.
Other researchers have already loaded hollow origami structures with drugs to target
specific types of cancer cells, created DNA «robots» that walk across surfaces, and mimicked the shape of viruses.
Cancer stem cells can be considered the most
dangerous type of cancer cells, as they appear to have an inherent resistance to the chemotherapeutic drugs used today.
Marcus stresses that SaGA can be applied to additional cell types or environments, or other
types of cancer cell behavior such as drug resistance.
As an aside, many
types of cancer cells do NOT have this adaptability and require glucose to thrive, which makes the ketogenic diet an effective therapy for combating cancer.
Working with colleagues in Hungary and University of Cambridge, the team led by Dr Korcsmáros used databases of genes known to be involved in cancer, or that show major differences between healthy and diseased tissues, along with other resources detailing protein interactions in the cell, to create computational models of the protein networks in
different types of cancer cells.
These compounds inhibit the growth of
several types of cancer cells, with minimal effects on the growth of non-cancerous cells, the researchers report in Nature Chemistry.
It has been known for some time that the bioactive compounds found in grape seed extract have the ability to selectively target
certain types of cancer cells.
In health, this gene helps to regulate DNA transcription, but a mutated version is found in
many types of cancer cell, where it helps them to proliferate quickly.
«The challenge is finding targets that exist on
other types of cancer cells but not on normal cells,» says pediatric oncologist Stephan Grupp of the Children's Hospital of Philadelphia, who worked with Porter on testing the treatment in mice.
Its drug Niraparib kills cancer cells by inhibiting the production of proteins called PARPs, which help repair damaged DNA strands, thereby hastening the death of
some types of cancer cells.
Production of the enzyme asparagine synthetase is deficient in ALL and several other
types of cancer cells, which are therefore unable to synthesize the amino acid asparagine.
Until now, the differences in
the types of cancer cells in a glioblastoma have prevented successful treatment, because some of the resistant tumor facets might reproduce more intensively under the chemotherapy.
As different cancers express different biomarkers, it might be possible to modify the molecular structure of the ruthenium molecule to target different
types of cancer cell.»
The silver complexes proved to be as effective as cisplatin in attacking
both types of cancer cells.
These cancer stem cells replenish themselves and produce the other
types of cancer cells, as normal stem cells produce other normal tissues.
They found that Fusobacterium nucleatum in the gut can stop chemotherapy from causing
a type of cancer cell death called apoptosis.
The discovery, which is described online in the journal Cell, may lead to new ways to trigger cell death in
some types of cancer cells.
The screening revealed coibamide A to be capable of killing many
types of cancer cells, but Ishmael decided to focus subsequent studies on two types in particular — brain tumors, or glioblastomas, and a breast cancer subtype known as triple negative breast cancer.
For this study, Silke Kiessling, a postdoctoral fellow on Nicolas Cermakian's team, successfully adjusted the gears of the internal clocks in two
types of cancer cells?
McKay and Tsai conclude that nucleostemin is involved in regulating the proliferation of both stem cells and at least
some types of cancer cells, they reported at a meeting here on 20 November and in the December issue of Genes & Development.
For some reason, pRB is turned off in
all types of cancer cells, leaving them with only cyclin A-cdk2 to regulate E2F.
Scientists have known that LPA is secreted by many
types of cancer cells, appears to promote the growth and spread of tumor cells, and that immune cells known as CD - 8 «killer» T cells have several receptors for LPA.
Of note, certain
types of cancer cell, including pancreatic and lung cancer cells, are heavily reliant on growth benefits brought by autophagy activation, therefore becoming «addicted» to autophagy.
«Researchers found that a unique strain of skin bacteria produces a chemical that kills several
types of cancer cells,» Dr. Bowe says.
The Swedish researchers concluded that extracts from organically grown strawberries halted cancer cell proliferation more effectively than extracts from conventionally grown ones, and in
both types of cancer cells.
«This unique strain of skin bacteria produces a chemical that kills several
types of cancer cells but does not appear to be toxic to normal cells,» Richard Gallo, chair of the department of dermatology at University of California, San Diego School of Medicine, and an author on the study, said in a statement.
And, anthocyanins also trigger apoptosis — or cell suicide — in several different
types of cancer cells.
Unfortunately, the study did find that limiting the availability of serine and glycine did not have the same cancer - reducing reaction in
all types of cancer cells.
Tests on animals and humans alike show that HAMLET kills over 40 different
types of cancer cells, all without harming healthy cells.
Research suggests cruciferous veggies have the ability to inhibit the growth of
some types of cancer cells and even stop others by reducing the production of free radicals.
In a study published this year in Current Drug Targets, a combination of tocotrienols and quercetin induced senescence and promoted apoptosis in many different
types of cancer cells, while delaying senescence in healthy cells and rejuvenating formerly healthy senescent cells.
A lab - based study showed that myrrh actually inhibited the growth in eight different
types of cancer cells.
Curcumin inhibits the growth and spread of different
types of cancer cells, in particular leukemia, hepatic, colorectal, pancreatic, gastric, prostate, breast, and oral cancers.
Kaempferol inhibits the growth of
some types of cancer cells, showing promising anti-tumor abilities for colon and pancreatic cancers.